Dialysis disequilibrium syndrome (DDS) is a rare but potentially life-threatening neurologic complication associated with hemodialysis (HD), particularly during initial treatments in patients with severe uremia. It is thought to result from rapid osmotic shifts between the plasma and the central nervous system during dialysis. We present the case of a 36-year-old woman with stage V… Continue reading Chaos in the Equilibrium: A Rare Complication of Dialysis
Tag: neuropathy
Optimising the Therapeutic Window: A Systematic Review and Network Meta-Analysis of Pregabalin Dosing Strategies for Painful Diabetic Neuropathy
Aims: Although pregabalin is a first-line therapy for painful #diabetic #polyneuropathy (PDPN), its optimal dose-response relationship remains unclear. We conducted a network meta-analysis to evaluate the efficacy and safety of fixed pregabalin dosages in PDPN patients.Materials and methods: We systematically searched major databases through October 2025 comparing various doses of pregabalin (75, 150, 300, and… Continue reading Optimising the Therapeutic Window: A Systematic Review and Network Meta-Analysis of Pregabalin Dosing Strategies for Painful Diabetic Neuropathy