The IR of opportunistic infections was highest for PM/DM cases (61.3/1000 person-years, 95% confidence interval [CI] 56.6–66.2), followed by SLE cases (43.1/1000 person-years, 95% CI 41.7–44.5), SSc cases (31.6/1000 person-years, 95% CI 28.3–35.1), RA cases (25.0/1000 person-years, 95% CI 24.4–25.7), and pSS cases (24.1/1000 person-years, 95% CI 23.1–25.2). Multivariable Cox analysis revealed that, relative to… Continue reading Comparing the burdens of opportunistic #infections among patients with systemic #rheumatic diseases: a nationally representative cohort study
Category: Infectivology
C-Reactive Protein Testing to Guide Antibiotic Prescribing for #COPD Exacerbations
Point-of-care testing of C-reactive protein (#CRP) may be a way to reduce unnecessary use of antibiotics without harming patients who have acute exacerbations of chronic obstructive pulmonary disease (COPD). A lower percentage of patients in the CRP-guided group than in the usual-care group received an antibiotic prescription at the initial consultation (47.7% vs. 69.7%, for… Continue reading C-Reactive Protein Testing to Guide Antibiotic Prescribing for #COPD Exacerbations
Stress related disorders and subsequent risk of life threatening #infections: population based sibling controlled cohort study
..144 919 individuals with stress related disorders (post-traumatic stress disorder (PTSD), acute stress reaction, adjustment disorder, and other stress reactions) identified from 1987 to 2013 ..Stress related disorders were associated with all studied life threatening infections, with the highest relative risk observed for meningitis (sibling based analysis 1.63 (1.23 to 2.16)) and endocarditis (1.57 (1.08 to… Continue reading Stress related disorders and subsequent risk of life threatening #infections: population based sibling controlled cohort study
Occurrence of #Salmonella, Campylobacter, Clostridium and Enterobacteriaceae in raw #meat-based diets for #dogs
The practice of feeding raw meat-based diets (RMBD) to dogs has increased in popularity in recent years. However, RMBD are based on offal that has not undergone any type of treatment to reduce the microbial content, so there is a risk of potential pathogenic microorganisms being present. Enterobacteriaceae were detected in all 60 samples and… Continue reading Occurrence of #Salmonella, Campylobacter, Clostridium and Enterobacteriaceae in raw #meat-based diets for #dogs
Association Between #Rotavirus Vaccination and Risk of #Intussusception Among Neonates and Infants
Twenty cases of definite intussusception were diagnosed within 31 days after rotavirus vaccination, with 11 cases (55%) in the vaccine group and 9 cases (45%) in the placebo group (RD, 0.17 per 10 000 infants [95% CI, −1.16 to 1.50 per 10 000 infants], P = .80; RR, 1.14 [95% CI, 0.49 to 2.64], P = .77). Seventy-four cases were reported… Continue reading Association Between #Rotavirus Vaccination and Risk of #Intussusception Among Neonates and Infants
Detection of Cytomegalovirus in Intestinal Tissue of Infants with Necrotizing Enterocolitis or Spontaneous Intestinal Perforation
To determine the frequency of detection of cytomegalovirus (CMV) in surgical or autopsy intestinal tissue from infants with necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP) of the small bowel. CMV was detected by PCR or IHC in 7 (4%) of 178 infants with surgical or autopsy- confirmed NEC (n = 6) or SIP (n… Continue reading Detection of Cytomegalovirus in Intestinal Tissue of Infants with Necrotizing Enterocolitis or Spontaneous Intestinal Perforation
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