Association of 15 common dietary factors with #tinnitus: a systematic review and meta-analysis of observational studies

Objective A systematic analysis was conducted to investigate the association between tinnitus incidence and daily dietary patterns.Design We conducted a systematic review and meta-analysis of observational studies.Data sources The PubMed, Embase, Web of Science and Cochrane Library databases were searched from their inception to 25 May 2024.Eligibility criteria for selecting studies We included observational studies… Continue reading Association of 15 common dietary factors with #tinnitus: a systematic review and meta-analysis of observational studies

#Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal #cancer

Diet, microbiome, inflammation and host genetics have been linked to colorectal cancer development; however, it is not clear whether and how these factors interact to promote carcinogenesis. Here we used Il10−/− mice colonized with bacteria previously associated with colorectal cancer: enterotoxigenic Bacteroides fragilis, Helicobacter hepaticus or colibactin-producing (polyketide synthase-positive (pks+)) Escherichia coli and fed either… Continue reading #Dietary fibre counters the oncogenic potential of colibactin-producing Escherichia coli in colorectal #cancer

Association of #Diet and #Waist-to-Hip Ratio With Brain Connectivity and #Memory in #Aging

Importance  Epidemiological studies suggest that lifestyle factors are associated with risk of dementia. However, few studies have examined the association of diet and waist to hip ratio (WHR) with hippocampus connectivity and cognitive health.Objective  To ascertain how longitudinal changes in diet quality and WHR during midlife are associated with hippocampal connectivity and cognitive function in… Continue reading Association of #Diet and #Waist-to-Hip Ratio With Brain Connectivity and #Memory in #Aging

Suboptimal #dietary patterns are associated with accelerated biological #aging in young adulthood: A study with twins

Background & aimsSuboptimal diets increase morbidity and mortality risk. Epigenetic clocks are algorithms that can assess health and lifespan, even at a young age, before clinical manifestations of diseases. We investigated the association between dietary patterns and biological aging in young adult twins.MethodsThe data were drawn from the population-based FinnTwin12 study and consisted of twins… Continue reading Suboptimal #dietary patterns are associated with accelerated biological #aging in young adulthood: A study with twins

#Dairy Consumption and the Colonic Mucosa-Associated Gut #Microbiota in Humans—A Preliminary Investigation

Background: Dairy consumption has been associated with various health outcomes that may be mediated by changes in gut microbiota. Methods: This cross-sectional study investigated the association between the colonic mucosa-associated gut microbiota and the self-reported intake of total dairy, milk, cheese, and yogurt. A total of 97 colonic mucosal biopsies collected from 34 polyp-free individuals… Continue reading #Dairy Consumption and the Colonic Mucosa-Associated Gut #Microbiota in Humans—A Preliminary Investigation

Effect of #broccoli sprout extract and baseline gut microbiota on fasting blood #glucose in #prediabetes: a randomized, placebo-controlled trial

More effective treatments are needed for impaired fasting glucose or glucose intolerance, known as prediabetes. Sulforaphane is an isothiocyanate that reduces hepatic gluconeogenesis in individuals with type 2 diabetes and is well tolerated when provided as a broccoli sprout extract (BSE). Here we report a randomized, double-blind, placebo-controlled trial in which drug-naive individuals with prediabetes… Continue reading Effect of #broccoli sprout extract and baseline gut microbiota on fasting blood #glucose in #prediabetes: a randomized, placebo-controlled trial

Associations Between #Polyphenol Intake, Cardiometabolic Risk Factors and Metabolic Syndrome in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)Author links open overlay panel

BackgroundFruit- and vegetable-rich diets may protect against metabolic syndrome (MetS), partly due to their high polyphenol content.ObjectivesThis study examined the association between dietary polyphenol intake, MetS risk, and cardiometabolic factors in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).MethodsA total of 6387 participants (mean age 49.8 y, 65% female) were included. Food intake was assessed… Continue reading Associations Between #Polyphenol Intake, Cardiometabolic Risk Factors and Metabolic Syndrome in the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)Author links open overlay panel

#Sweetener #aspartame aggravates #atherosclerosis through insulin-triggered inflammation

Highlights•Aspartame increases insulin levels through parasympathetic activation•An insulin-dependent mechanism of the aspartame-aggravated atherosclerosis•The CX3CL1-CX3CR1 signaling mediates insulin-induced endothelial inflammation•A CX3CL1-CX3CR1-dependent mechanism of aspartame-exacerbated atherosclerosis SummaryConsumption of artificial sweeteners (ASWs) in various foods and beverages has been linked to an increased risk of cardiovascular diseases (CVDs). However, molecular mechanisms underlying ASW-associated CVD remain unknown. Here, we… Continue reading #Sweetener #aspartame aggravates #atherosclerosis through insulin-triggered inflammation

#Egg Consumption: Trends Over 48 Years, Patterns Across the Lifespan, and Predictors of Intake

Background/Objectives: Eggs are an excellent nutritional source. However, historical associations of dietary cholesterol with serum cholesterol and cardiovascular disease, along with restrictive dietary guidelines may have been barriers to egg consumption. This study examines trends over time, patterns, and predictors of egg consumption in individuals followed for 48 years, and current barriers to usage. Methods:… Continue reading #Egg Consumption: Trends Over 48 Years, Patterns Across the Lifespan, and Predictors of Intake