Importance Estimating global lives and life-years saved is important to put into perspective the benefits of COVID-19 vaccination. Prior studies have focused mainly on the pre-Omicron period or only on specific regions, and lack crucial life-year calculations and often depend on strong modeling assumptions with unaccounted uncertainty.Objective To calculate the lives and life-years saved by… Continue reading Global Estimates of #Lives and Life-Years Saved by #COVID-19 #Vaccination During 2020-2024
Tag: Vaccines
Association Between #COVID-19 #Vaccination and #Neuropsychiatric Conditions
Introduction: This study explores the potential associations between COVID-19 vaccination and neuropsychiatric conditions. Methods: Data were collected from the CDC and FDA. The VAERS database was queried from January 1, 1990, to December 27, 2024, for adverse events (AEs) involving neuropsychiatric complications following COVID-19 vaccination. The timeframe included 420 months for all vaccines except COVID-19… Continue reading Association Between #COVID-19 #Vaccination and #Neuropsychiatric Conditions
#Thimerosal as a #Vaccine #Preservative
Age-adjusted non-COVID-19 #mortality rates according to the #COVID-19 vaccination status
Excess mortality has been observed in several countries since 2021 and has not yet been explained. The aim of this study was to determine whether the age-adjusted mortality rates of non-COVID-19 deaths differed between those who had received one, two, three or four doses compared with the unvaccinated. Data were obtained from the Office for… Continue reading Age-adjusted non-COVID-19 #mortality rates according to the #COVID-19 vaccination status
Impact of #mRNA and Inactivated COVID-19 Vaccines on #Ovarian Reserve
Objectives: This study aimed to elucidate the effects of messenger RNA (mRNA) and inactivated coronavirus disease 2019 (COVID-19) vaccines on ovarian histology and reserve in rats. Methods: Thirty female Wistar albino rats, aged 16–24 weeks, were randomly divided into three groups (n = 10): control, mRNA vaccine, and inactivated vaccine groups. Each vaccine group received… Continue reading Impact of #mRNA and Inactivated COVID-19 Vaccines on #Ovarian Reserve
Repeated #COVID-19 #Vaccination as a Poor Prognostic Factor in Pancreatic #Cancer: A Retrospective, Single-Center Cohort Study
AbstractThe COVID-19 vaccine is a significant technological advancement with widespread global use. However, its effect on cancer immunity, particularly with repeated vac-cinations, remains unclear. We aimed to investigate the relationship between repeated vaccinations and pancreatic cancer (PC) prognosis. Additionally, we examined serum IgG4 levels, known to be an immune suppressor and increased with repeated vac-cinations.… Continue reading Repeated #COVID-19 #Vaccination as a Poor Prognostic Factor in Pancreatic #Cancer: A Retrospective, Single-Center Cohort Study
COVID-19 #vaccines and #adverse events of special interest: A multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated individuals
AbstractBackground: The Global COVID Vaccine Safety (GCoVS) Project, established in 2021 under the multinational Global Vaccine Data Network™ (GVDN®), facilitates comprehensive assessment of vaccine safety. This study aimed to evaluate the risk of adverse events of special interest (AESI) following COVID-19 vaccination from 10 sites across eight countries.Methods: Using a common protocol, this observational cohort… Continue reading COVID-19 #vaccines and #adverse events of special interest: A multinational Global Vaccine Data Network (GVDN) cohort study of 99 million vaccinated individuals
The protective role of vitamin #D in BNT162b2 vaccine-related acute #myocarditis
Introduction: Vaccine-related myocarditis is recognized as a rare but important complication, especially after mass-scale mRNA COVID-19 vaccination. Knowledge regarding how to minimize the risk is limited. As NK cells can mediate acute myocarditis after mRNA COVID-19 vaccination and vitamin D may inhibit NK cells via cytokine modulation, we hypothesize that the myocarditis side effect is… Continue reading The protective role of vitamin #D in BNT162b2 vaccine-related acute #myocarditis
OpenSAFELY: Effectiveness of #COVID-19 #vaccination in #children and sadolescents
Background Children and adolescents in England were offered BNT162b2 as part of the national COVID-19 vaccine roll out from September 2021. We assessed the safety and effectiveness of first and second dose BNT162b2 COVID-19 vaccination in children and adolescents in England.Methods With the approval of NHS England, we conducted an observational study in the OpenSAFELY-TPP… Continue reading OpenSAFELY: Effectiveness of #COVID-19 #vaccination in #children and sadolescents
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