30 – Early-Life #Tobacco Exposure, Genetic Risk, and Incident Type 2 #Diabetes

Tobacco exposure in adulthood is a well-established risk factor for type 2 diabetes (T2D), but how early-life tobacco exposure implicates in the development of T2D as well as whether this association varies by different genetic predisposition to T2D are unclear. Addressing these gaps may provide novel insights into early interventions of T2D.Hypothesis We hypothesized that tobacco… Continue reading 30 – Early-Life #Tobacco Exposure, Genetic Risk, and Incident Type 2 #Diabetes

The contribution of secondhand tobacco #smoke to blood #lead levels in US children and adolescents: a cross-sectional analysis of NHANES 2015–2018

Lead is a major developmental neurotoxicant in children, and tobacco smoke has been suggested as a source of lead exposure in vulnerable populations. This study evaluates the contribution of secondhand tobacco smoke (SHS) to blood lead levels (BLLs) in children and adolescents.MethodsWe analyze data from 2,815 participants aged 6–19 years who participated in the National Health… Continue reading The contribution of secondhand tobacco #smoke to blood #lead levels in US children and adolescents: a cross-sectional analysis of NHANES 2015–2018

Trajectories of asthma symptom presenting as wheezing and their associations with family environmental factors among children in Australia: evidence from a national birth cohort study

Objectives Asthma is one of the greatest health burdens, yet contributors to asthma symptom trajectories are understudied in Australian children. We aimed to assess the trajectories of asthma symptom and their associations with several family environmental factors during the childhood period in Australia. Design Secondary analysis from a cross-sequential cohort study. Setting Nationwide representative data… Continue reading Trajectories of asthma symptom presenting as wheezing and their associations with family environmental factors among children in Australia: evidence from a national birth cohort study

Childhood Tobacco Smoke Exposure and Risk of Atrial #Fibrillation in Adulthood

Of 2,816 Offspring cohort participants with at least 1 parent in the Original cohort, 82% were exposed to parental smoking. For every pack/day increase in parental smoking, there was an 18% increase in offspring AF incidence (adjusted hazard ratio [HR]: 1.18; 95% confidence interval [CI]: 1.00 to 1.39; p = 0.04). Additionally, parental smoking was… Continue reading Childhood Tobacco Smoke Exposure and Risk of Atrial #Fibrillation in Adulthood