#Vagus nerve stimulation therapy for treatment-resistant #PTSD

BackgroundPosttraumatic stress disorder (PTSD) is common and debilitating, and many individuals do not respond to existing therapies. We developed a fundamentally novel neuromodulation-based therapy for treatment-resistant PTSD. This approach is premised on coupling prolonged exposure therapy, a first-line evidence-based cognitive behavioral therapy that directs changes within fear networks, with concurrent delivery of short bursts of… Continue reading #Vagus nerve stimulation therapy for treatment-resistant #PTSD

Posttraumatic #Stress Disorder and Obstructive Sleep #Apnea in Twins

Key PointsQuestion  What is the association of posttraumatic stress disorder (PTSD) with obstructive sleep apnea (OSA) after accounting for acknowledged medical risk factors for OSA?Findings  In a cross-sectional study of 132 older male veteran twins discordant for PTSD undergoing in-laboratory polysomnography, current PTSD diagnosis and symptoms were associated independently with OSA, even after controlling for demographics, behavioral… Continue reading Posttraumatic #Stress Disorder and Obstructive Sleep #Apnea in Twins

Morning blue light treatment improves sleep complaints, symptom severity, and retention of fear extinction memory in post-traumatic stress disorder

Disrupted sleep is a major feature in numerous clinical disorders and is related to decrements in affective memory processing. The prevalence of sleep disruption in post-traumatic stress disorder (PTSD) is suggested to be a key feature that exacerbates the impaired ability to recall extinction memories during experimental fear conditioning. We hypothesized that an intervention employing… Continue reading Morning blue light treatment improves sleep complaints, symptom severity, and retention of fear extinction memory in post-traumatic stress disorder

Cognitive Behavioral Therapy for Veterans With Comorbid Posttraumatic Headache and Posttraumatic Stress Disorder SymptomsA Randomized Clinical Trial

Importance Posttraumatic headache is the most disabling complication of mild traumatic brain injury. Posttraumatic stress disorder (PTSD) symptoms are often comorbid with posttraumatic headache, and there are no established treatments for this comorbidity. Objective To compare cognitive behavioral therapies (CBTs) for headache and PTSD with treatment per usual (TPU) for posttraumatic headache attributable to mild… Continue reading Cognitive Behavioral Therapy for Veterans With Comorbid Posttraumatic Headache and Posttraumatic Stress Disorder SymptomsA Randomized Clinical Trial

Exploring Posttraumatic #Stress Disorder as a #Cardiovascular Risk Factor in Women VeteransThe Heart of the Matter

The connection between emotional and physical health has long been recognized, with a great deal of research focusing on the risk of cardiovascular disease (CVD). The landmark INTERHEART study1 of nearly 30 000 people from 52 countries found that psychosocial factors, including depression and stressful life events, accounted for approximately one-third of the population-attributable risk of… Continue reading Exploring Posttraumatic #Stress Disorder as a #Cardiovascular Risk Factor in Women VeteransThe Heart of the Matter

A Pilot Randomized Controlled Trial of Transcendental #Meditation as Treatment for #Posttraumatic Stress Disorder in Veterans

Preliminary studies have demonstrated the efficacy of Transcendental Meditation (TM) for treating posttraumatic stress disorder (PTSD). The present study extended previous research with a pilot trial of TM as a treatment for PTSD via a single‐blinded, randomized controlled design. veterans with PTSD (N = 40) were assigned to a TM intervention or treatment‐as‐usual (TAU) control… Continue reading A Pilot Randomized Controlled Trial of Transcendental #Meditation as Treatment for #Posttraumatic Stress Disorder in Veterans

Post-traumatic growth during the #COVID-19 pandemic in carers of children in Portugal and the UK: cross-sectional online survey

Although the negative effects of the COVID-19 pandemic on mental health have attracted interest, little attention has focused on its positive effects and possible post-traumatic growth. Aims To assess anxiety, well-being and post-traumatic growth in carers of children aged 6–16 years in Portugal and the UK. Method A cross-sectional online survey of volunteers conducted at… Continue reading Post-traumatic growth during the #COVID-19 pandemic in carers of children in Portugal and the UK: cross-sectional online survey

Post-traumatic stress disorder ( #PTSD ) in mid-age and older adults differs by immigrant status and ethnicity, #nutrition, and other determinants of health in the Canadian Longitudinal Study on Aging (CLSA)

This study aimed to address knowledge gaps about post-traumatic stress disorder (PTSD) in mid-age and older adults, with particular attention to the relationship of PTSD with nutrition and with ethnicity and immigrant status. Methods Binary logistic regression analysis of weighted comprehensive cohort data from the baseline Canadian Longitudinal Study on Aging (CLSA; n = 27,211) was conducted… Continue reading Post-traumatic stress disorder ( #PTSD ) in mid-age and older adults differs by immigrant status and ethnicity, #nutrition, and other determinants of health in the Canadian Longitudinal Study on Aging (CLSA)

A Randomized Controlled Trial of Repeated #Ketamine Administration for Chronic Posttraumatic Stress Disorder

Posttraumatic stress disorder (PTSD) is a chronic and disabling disorder, for which available pharmacotherapies have limited efficacy. The authors’ previous proof-of-concept randomized controlled trial of single-dose intravenous ketamine infusion in individuals with PTSD showed significant and rapid PTSD symptom reduction 24 hours postinfusion. The present study is the first randomized controlled trial to test the… Continue reading A Randomized Controlled Trial of Repeated #Ketamine Administration for Chronic Posttraumatic Stress Disorder