Editor’s summaryPolycystic ovary syndrome is a common endocrine condition in women of reproductive age. Its manifestations include androgen excess and other hormonal changes, menstrual cycle alterations, infertility, and metabolic abnormalities. Artemisinins are plant-derived compounds that are best known for their antimalarial properties but have also been shown to have some beneficial metabolic effects. Liu et al.… Continue reading #Artemisinins ameliorate #polycystic ovarian syndrome by mediating LONP1-CYP11A1 interaction
Tag: polycystic-ovary
Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome
Highlights•PCOS-sons are often obese and have dyslipidemia•miRNAs altered in the serum of PCOS-sons and women with PCOS targets PCOS-risk genes•Small RNAs present in sperm imply transgenerational transmission of phenotype in mice•Shared miRNAs between mouse sperm of F1–F3 generations and human serum are revealedSummaryThe transgenerational maternal effects of polycystic ovary syndrome (PCOS) in female progeny are being… Continue reading Transgenerational transmission of reproductive and metabolic dysfunction in the male progeny of polycystic ovary syndrome
Trends, Predictors, and Outcomes of Cardiovascular Complications Associated With Polycystic Ovary Syndrome During Delivery Hospitalizations: A National Inpatient Sample Analysis (2002–2019)
BackgroundWomen with polycystic ovary syndrome (PCOS) have an increased risk of pregnancy‐associated complications. However, data on peripartum cardiovascular complications remain limited. Hence, we investigated trends, outcomes, and predictors of cardiovascular complications associated with PCOS diagnosis during delivery hospitalizations in the United States.Methods and ResultsWe used data from the National Inpatient Sample (2002–2019). International Classification of… Continue reading Trends, Predictors, and Outcomes of Cardiovascular Complications Associated With Polycystic Ovary Syndrome During Delivery Hospitalizations: A National Inpatient Sample Analysis (2002–2019)
Efficacy of very low calorie ketogenic diet in obese PCOS: a randomized controlled study
Background: Very low-calorie ketogenic diet (VLCKD) was shown to be effective in reducing weight and insulin resistance (IR) in obese patients. Considering that IR is very common in women with polycystic ovary syndrome (PCOS), and that IR worsens hyperandrogenism, ovulatory disfunction, and body fat accumulation, conceivably VLCKD could alleviate PCOS manifestations in the obese phenotype.… Continue reading Efficacy of very low calorie ketogenic diet in obese PCOS: a randomized controlled study
Effect of pharmacological interventions on lipid profiles and C-reactive protein in polycystic ovary syndrome: A systematic review and meta-analysis
Polycystic ovary syndrome (PCOS) is a heterogeneous condition affecting women of reproductive age. It is associated with dyslipidaemia and elevated plasma C-reactive protein (CRP), which increase the risks of cardiovascular disease (CVD). ObjectiveTo review the existing evidence on the effects of different pharmacological interventions on lipid profiles and CRP of women with PCOS. Data SourcesWe… Continue reading Effect of pharmacological interventions on lipid profiles and C-reactive protein in polycystic ovary syndrome: A systematic review and meta-analysis
OR10-1 – Efficacy of High-Intensity Intermittent #Training for Improving Cardio-Metabolic Health in Women With #Polycystic Ovary Syndrome
Polycystic ovary syndrome (PCOS) is a common and complex endocrinopathy with significant metabolic and reproductive manifestations, carrying a major health and economic burden. Consistent improvements in clinical outcomes have been reported as a result of exercise training, but shortfalls with exercise prescription are evident. Research suggests that high-intensity intermittent training (HIIT) is feasible, well tolerated… Continue reading OR10-1 – Efficacy of High-Intensity Intermittent #Training for Improving Cardio-Metabolic Health in Women With #Polycystic Ovary Syndrome
Regular Mindful #Yoga Practice as a Method to Improve Androgen Levels in Women With Polycystic #Ovary Syndrome: A Randomized, Controlled Trial
Holistic approaches are needed to complement existing therapies for polycystic ovary syndrome (PCOS), a common disorder affecting the health of reproductive-aged females.. ..epiandrosterone, androstenedione, body mass index, waist-to-hip ratio, fasting blood glucose and insulin levels, and anxiety and depression scores. Results: Twenty-two women completed the 3-month intervention period, 13 in the mindful yoga group and… Continue reading Regular Mindful #Yoga Practice as a Method to Improve Androgen Levels in Women With Polycystic #Ovary Syndrome: A Randomized, Controlled Trial
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