Background Vigorous intermittent lifestyle physical activity (VILPA) refers to brief bouts of intense physical activity embedded into daily life.Objective To examine sex differences in the dose–response association of VILPA with major adverse cardiovascular events (MACE) and its subtypes.Methods Using multivariable-adjusted cubic splines, we examined the associations of daily VILPA duration with overall MACE and its… Continue reading Device-measured vigorous intermittent lifestyle #physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences
Tag: physical-activity
Device-Measured 24-Hour Movement Behaviors and Blood #Pressure: A 6-Part Compositional Individual Participant Data Analysis in the ProPASS Consortium
BACKGROUND:Blood pressure (BP)–lowering effects of structured exercise are well-established. Effects of 24-hour movement behaviors captured in free-living settings have received less attention. This cross-sectional study investigated associations between a 24-hour behavior composition comprising 6 parts (sleeping, sedentary behavior, standing, slow walking, fast walking, and combined exercise-like activity [eg, running and cycling]) and systolic BP (SBP)… Continue reading Device-Measured 24-Hour Movement Behaviors and Blood #Pressure: A 6-Part Compositional Individual Participant Data Analysis in the ProPASS Consortium
#Accelerometer-derived ‘weekend warrior’ physical #activity pattern and #brain health
Extensive evidence shows the beneficial effect of adhering to a regular physical activity (PA) pattern on brain health. However, whether the ‘weekend warrior’ pattern, characterized by concentrated moderate-to-vigorous PA (MVPA) over 1–2 days, is associated with brain health is unclear. Here, we perform a prospective cohort study including 75,629 participants from the UK Biobank with validated… Continue reading #Accelerometer-derived ‘weekend warrior’ physical #activity pattern and #brain health
#Sitting Time and Its Interaction With #Physical Activity in Relation to All-Cause and #Heart Disease Mortality in U.S. Adults With Diabetes
To evaluate whether associations between sitting time and all-cause and heart disease mortality are modified by physical activity in adults with diabetes.RESEARCH DESIGN AND METHODSData came from 6,335 U.S. adults with diabetes from National Health and Nutrition Examination Survey 2007–2018 (baseline), with mortality follow-up through 2019. Sitting time and moderate to vigorous physical activity (MVPA)… Continue reading #Sitting Time and Its Interaction With #Physical Activity in Relation to All-Cause and #Heart Disease Mortality in U.S. Adults With Diabetes
National, regional, and global trends in insufficient #physical activity among adults from 2000 to 2022: a pooled analysis of 507 population-based surveys with 5·7 million participants
BackgroundInsufficient physical activity increases the risk of non-communicable diseases, poor physical and cognitive function, weight gain, and mental ill-health. Global prevalence of adult insufficient physical activity was last published for 2016, with limited trend data. We aimed to estimate the prevalence of insufficient physical activity for 197 countries and territories, from 2000 to 2022.MethodsWe collated… Continue reading National, regional, and global trends in insufficient #physical activity among adults from 2000 to 2022: a pooled analysis of 507 population-based surveys with 5·7 million participants
Accelerometer-measured intensity-specific physical activity, genetic risk and incident type 2 diabetes: a prospective cohort study
Objective Although 30 min/day of moderate-intensity physical activity is suggested for preventing type 2 diabetes (T2D), the current recommendations exclusively rely on self-reports and rarely consider the genetic risk. We examined the prospective dose-response relationships between total/intensity-specific physical activity and incident T2D accounting for and stratified by different levels of genetic risk.Methods This prospective cohort study was… Continue reading Accelerometer-measured intensity-specific physical activity, genetic risk and incident type 2 diabetes: a prospective cohort study
Timing of physical activity in relation to liver fat content and insulin resistance
Aims/hypothesisWe hypothesised that the insulin-sensitising effect of physical activity depends on the timing of the activity. Here, we examined cross-sectional associations of breaks in sedentary time and timing of physical activity with liver fat content and insulin resistance in a Dutch cohort.MethodsIn 775 participants of the Netherlands Epidemiology of Obesity (NEO) study, we assessed sedentary… Continue reading Timing of physical activity in relation to liver fat content and insulin resistance
Causal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults
BackgroundThe hard endpoint of death is one of the most significant outcomes in both clinical practice and research settings. Our goal was to discover direct causes of longevity from medically accessible data.MethodsUsing a framework that combines local causal discovery algorithms with discovery of maximally predictive and compact feature sets (the “Markov boundaries” of the response)… Continue reading Causal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults
Association of Leisure Time Physical Activity Types and Risks of All-Cause, Cardiovascular, and Cancer Mortality Among Older Adults
Higher amounts of physical activity are associated with increased longevity. However, whether different leisure time physical activity types are differentially associated with mortality risk is not established.Objectives To examine whether participation in equivalent amounts of physical activity (7.5 to <15 metabolic equivalent of task [MET] hours per week) through different activity types is associated with… Continue reading Association of Leisure Time Physical Activity Types and Risks of All-Cause, Cardiovascular, and Cancer Mortality Among Older Adults
2 Medical News 