#Mindfulness-based cognitive therapy versus treatment as usual after non-remission with NHS Talking Therapies high-intensity psychological therapy for depression: a UK-based clinical effectiveness and cost-effectiveness randomised, controlled, superiority trial

BackgroundNon-remission after psychological therapy for major depressive disorder is common, yet there are no established further-line treatments. In the UK National Health Service (NHS) Talking Therapies programme, about 50% of patients with depression who come to the end of the stepped care pathway do not show remission of symptoms. We aimed to investigate whether mindfulness-based… Continue reading #Mindfulness-based cognitive therapy versus treatment as usual after non-remission with NHS Talking Therapies high-intensity psychological therapy for depression: a UK-based clinical effectiveness and cost-effectiveness randomised, controlled, superiority trial

#Mindfulness Meditation vs #Escitalopram for Treatment of #Anxiety DisordersSecondary Analysis of a Randomized Clinical Trial

IntroductionMindfulness-based interventions, such as mindfulness-based stress reduction (MBSR), have shown efficacy for anxiety disorders.1 We previously demonstrated that 8 weeks of MBSR was noninferior to escitalopram for treatment of anxiety disorders in a fully powered, multisite, noninferiority parallel-group randomized clinical trial with a predetermined margin.2 We present secondary outcomes of the trial, including patient-reported anxiety,… Continue reading #Mindfulness Meditation vs #Escitalopram for Treatment of #Anxiety DisordersSecondary Analysis of a Randomized Clinical Trial

Self-administered #mindfulness interventions reduce #stress in a large, randomized controlled multi-site study

Mindfulness witnessed a substantial popularity surge in the past decade, especially as digitally self-administered interventions became available at relatively low costs. Yet, it is uncertain whether they effectively help reduce stress. In a preregistered (OSF https://doi.org/10.17605/OSF.IO/UF4JZ; retrospective registration at ClinicalTrials.gov NCT06308744) multi-site study (nsites = 37, nparticipants = 2,239, 70.4% women, Mage = 22.4, s.d.age = 10.1, all fluent English speakers), we experimentally tested whether four single,… Continue reading Self-administered #mindfulness interventions reduce #stress in a large, randomized controlled multi-site study

The effect of mindfulness and motivational interviewing along with neuromuscular exercises on pain, function, and balance of women affected by knee osteoarthritis: a rater-blinded randomized controlled clinical trial

This study aimed to evaluate the effect of motivational interviewing (MI) and mindfulness (MF) added to neuromuscular (NM) exercises on improving pain, function, balance, and quality of life in patients with knee osteoarthritis (KOA).MethodsThis randomized clinical trial was conducted on sixty patients who were randomly assigned to the MI + NM, MF + NM, and NM groups. The groups… Continue reading The effect of mindfulness and motivational interviewing along with neuromuscular exercises on pain, function, and balance of women affected by knee osteoarthritis: a rater-blinded randomized controlled clinical trial

Neural Signatures of Pain Modulation in Short-Term and Long-Term Mindfulness Training: A Randomized Active-Control Trial

Mindfulness-based interventions are widely used to target pain, yet their neural mechanisms of action are insufficiently understood. The authors studied neural and subjective pain response in a randomized active-control trial of mindfulness-based stress reduction (MBSR) alongside long-term meditation practitioners.Methods:Healthy participants (N=115) underwent functional neuroimaging during a thermal acute pain task before and after random assignment… Continue reading Neural Signatures of Pain Modulation in Short-Term and Long-Term Mindfulness Training: A Randomized Active-Control Trial

Disentangling self from pain: mindfulness meditation-induced pain relief is driven by thalamic-default mode network decoupling

For millenniums, mindfulness was thought to diminish pain by reducing the influence of self-appraisals of noxious sensations. Today, mindfulness meditation is a highly popular and effective pain therapy that is thought to engage multiple, non-placebo related mechanisms to attenuate pain. Recent evidence suggests that mindfulness meditation-induced pain relief is associated with the engagement of unique… Continue reading Disentangling self from pain: mindfulness meditation-induced pain relief is driven by thalamic-default mode network decoupling

Online #Mindfulness May Target Psychological #Distress and Mental Health during #COVID-19

The COVID-19 pandemic has dramatically affected mental health, creating an urgent need for convenient and safe interventions to improve well-being. Online mindfulness interventions show promise for improving depression, anxiety, and general well-being. Objective To assess: 1) the impact of online mindfulness on psychological distress, 2) altruistic efforts, and 3) the quantity, quality, and availability of… Continue reading Online #Mindfulness May Target Psychological #Distress and Mental Health during #COVID-19

Cognitive Factors Associated with Frequency of #Eating Out and Eating Takeout among Latinas

Higher frequency of eating outside the home can be an unhealthy behavior that may contribute to higher rates of obesity among Latinas, a disproportionately affected group. There is a growing need to understand potentially modifiable factors (eg, dispositional mindfulness, self-efficacy, nutrition knowledge) associated with higher frequency of eating outside the home in this population. This… Continue reading Cognitive Factors Associated with Frequency of #Eating Out and Eating Takeout among Latinas

Outcomes of Online #Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms A Randomized Clinical Trial

Patients with residual depressive symptoms face a gap in care because few resources, to date, are available to manage the lingering effects of their illness.. To evaluate the effectiveness for treating residual depressive symptoms with Mindful Mood Balance (MMB), a web-based application that delivers mindfulness-based cognitive therapy, plus usual depression care compared with usual depression… Continue reading Outcomes of Online #Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms A Randomized Clinical Trial