2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood #Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice #Guidelines

The “2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults” retires and replaces the “2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults.”METHODS:A comprehensive literature search was conducted from December 2023 to June 2024 to identify clinical studies, reviews, and other… Continue reading 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood #Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice #Guidelines

Low-Calorie, High-Protein Ketogenic #Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with #Obesity with High-Normal Blood Pressure or Grade I #Hypertension: The Keto–Salt Pilot Study

Background and Objective: Dietary interventions are the first-line treatment for overweight individuals (OW) and individuals with obesity (OB) with high-normal blood pressure (BP) or grade I hypertension, especially when at low-to-moderate cardiovascular risk (CVR). However, current guidelines do not specify the most effective dietary approach for optimising cardiovascular and metabolic outcomes in this population. This… Continue reading Low-Calorie, High-Protein Ketogenic #Diet Versus Low-Calorie, Low-Sodium, and High-Potassium Mediterranean Diet in Overweight Patients and Patients with #Obesity with High-Normal Blood Pressure or Grade I #Hypertension: The Keto–Salt Pilot Study

#Spironolactone vs #Amiloride for Resistant #HypertensionA Randomized Clinical Trial

Importance  Amiloride has been proposed as an alternative to spironolactone for treating resistant hypertension. However, no randomized clinical trials have compared the efficacy of spironolactone and amiloride in patients with resistant hypertension.Objective  To determine whether amiloride is noninferior to spironolactone in reducing home-measured systolic blood pressure (SBP) in patients with resistant hypertension.Design, Setting, and Participants … Continue reading #Spironolactone vs #Amiloride for Resistant #HypertensionA Randomized Clinical Trial

Short #Sleep Duration and #Hypertension: A Double Hit for the #Brain

Short sleep duration has been associated with an increased risk of cognitive impairment and dementia. Short sleep is associated with elevated blood pressure, yet the combined insult of short sleep and hypertension on brain health remains unclear. We assessed whether the association of sleep duration with cognition and vascular brain injury was moderated by hypertensive… Continue reading Short #Sleep Duration and #Hypertension: A Double Hit for the #Brain

#Arm Position and Blood #Pressure ReadingsThe ARMS Crossover Randomized Clinical Trial

Key PointsQuestion  What is the effect of commonly used arm positions on blood pressure (BP) measurements compared to the standard, recommended position?Findings  This crossover randomized clinical trial of 133 adults showed that supporting the arm on the lap overestimated systolic BP by 3.9 mm Hg and diastolic BP by 4.0 mm Hg. An unsupported arm… Continue reading #Arm Position and Blood #Pressure ReadingsThe ARMS Crossover Randomized Clinical Trial

Low-Dose Triple-Pill vs Standard-Care Protocols for #Hypertension Treatment in NigeriaA Randomized Clinical Trial

Importance  With the high burden of hypertension in sub-Saharan Africa, there is a need for effective, safe and scalable treatment strategies.Objective  To compare, among Black African adults, the effectiveness and safety of a novel low-dose triple-pill protocol compared with a standard-care protocol for blood pressure lowering.Design and Setting  Randomized, parallel-group, open-label, multicenter trial conducted in public hospital–based family medicine… Continue reading Low-Dose Triple-Pill vs Standard-Care Protocols for #Hypertension Treatment in NigeriaA Randomized Clinical Trial

Effect of timed dosing of usual #antihypertensives according to patient chronotype on #cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study

BackgroundTiming drug administration to endogenous circadian rhythms may enhance treatment efficacy. In the Chronotype sub-study of the Treatment in Morning versus Evening (TIME) clinical trial we examined whether timing of usual antihypertensive medications according to patient chronotype (a behavioural marker of personal circadian rhythm) may influence clinical cardiovascular outcomes.MethodsThis was a cohort sub-study of TIME,… Continue reading Effect of timed dosing of usual #antihypertensives according to patient chronotype on #cardiovascular outcomes: the Chronotype sub-study cohort of the Treatment in Morning versus Evening (TIME) study

Effect of #Tai Chi vs Aerobic #Exercise on Blood #Pressure in Patients With PrehypertensionA Randomized Clinical Trial

Importance  Prehypertension increases the risk of developing hypertension and other cardiovascular diseases. Early and effective intervention for patients with prehypertension is highly important.Objective  To assess the efficacy of Tai Chi vs aerobic exercise in patients with prehypertension.Design, Setting, and Participants  This prospective, single-blinded randomized clinical trial was conducted between July 25, 2019, and January 24, 2022, at 2… Continue reading Effect of #Tai Chi vs Aerobic #Exercise on Blood #Pressure in Patients With PrehypertensionA Randomized Clinical Trial

Association between #tomato consumption and #blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial

Clinical studies have produced conflicting evidence on the effects of the consumption of tomatoes on blood pressure, and there are limited data from epidemiologic studies. This study assesses whether tomato consumption (Solanum lycopersicum L.) is associated with systolic and diastolic blood pressure, and the risk of hypertension in a prospective 3-year longitudinal study in older adults… Continue reading Association between #tomato consumption and #blood pressure in an older population at high cardiovascular risk: observational analysis of PREDIMED trial