Research on the effect of oral contraceptive (OC) use on the risk of depression shows inconsistent findings, especially in adult OC users. One possible reason for this inconsistency is the omission of women who discontinue OCs due to adverse mood effects, leading to healthy user bias. To address this issue, we aim to estimate the… Continue reading Population-based cohort study of oral contraceptive use and risk of depression
Tag: depression
High ultra-processed food consumption is associated with elevated psychological distress as an indicator of depression in adults from the Melbourne Collaborative Cohort Study
BackgroundFew studies have tested longitudinal associations between ultra-processed food consumption and depressive outcomes. As such, further investigation and replication are necessary. The aim of this study is to examine associations of ultra-processed food intake with elevated psychological distress as an indicator of depression after 15 years.MethodData from the Melbourne Collaborative Cohort Study (MCCS) were analysed (n = 23,299).… Continue reading High ultra-processed food consumption is associated with elevated psychological distress as an indicator of depression in adults from the Melbourne Collaborative Cohort Study
High fried food consumption impacts anxiety and depression due to lipid metabolism disturbance and neuroinflammation
To address a crucial knowledge deficiency concerning the correlation between fried food consumption and the risk of anxiety and depression, here we revealed that frequent fried food consumption is strongly associated with a higher risk of anxiety and depression. Notably, acrylamide is a representative contaminant in fried foods, thereby further elucidating its toxicological mode of… Continue reading High fried food consumption impacts anxiety and depression due to lipid metabolism disturbance and neuroinflammation
Music to improve sleep quality in adults with depression-related insomnia (MUSTAFI): randomized controlled trial
Background Insomnia in depression is common and difficult to resolve. Unresolved depression-related sleep disturbances increase risk of relapse at high costs for individuals and society. Trials have suggested music for insomnia in various populations, but there is little research on the effectiveness of music for depression-related insomnia. Methods We examined the efficacy of a music… Continue reading Music to improve sleep quality in adults with depression-related insomnia (MUSTAFI): randomized controlled trial
Depressive Symptoms and Risk of Acute Stroke: INTERSTROKE Case-Control Study
Depression has been reported to be a risk factor for acute stroke, based largely on studies in high-income countries. In the INTERSTROKE study, we explored the contribution of depressive symptoms to acute stroke risk and 1-month outcome across regions of the world, within subpopulations and by stroke typeMethodsINTERSTROKE is an international case-control study of risk… Continue reading Depressive Symptoms and Risk of Acute Stroke: INTERSTROKE Case-Control Study
Effectiveness of physical activity interventions for improving depression, anxiety and distress: an overview of systematic reviews
Objective To synthesise the evidence on the effects of physical activity on symptoms of depression, anxiety and psychological distress in adult populations.Design Umbrella review.Data sources Twelve electronic databases were searched for eligible studies published from inception to 1 January 2022.Eligibility criteria for selecting studies Systematic reviews with meta-analyses of randomised controlled trials designed to increase… Continue reading Effectiveness of physical activity interventions for improving depression, anxiety and distress: an overview of systematic reviews
Gut microbiome-wide association study of depressive symptoms
Depression is one of the most poorly understood diseases due to its elusive pathogenesis. There is an urgency to identify molecular and biological mechanisms underlying depression and the gut microbiome is a novel area of interest. Here we investigate the relation of fecal microbiome diversity and composition with depressive symptoms in 1,054 participants from the… Continue reading Gut microbiome-wide association study of depressive symptoms
Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians
...Recommendation 1a:ACP recommends monotherapy with either cognitive behavioral therapy or a second-generation antidepressant as initial treatment in patients in the acute phase of moderate to severe major depressive disorder (strong recommendation; moderate-certainty evidence).Recommendation 1b:ACP suggests combination therapy with cognitive behavioral therapy and a second-generation antidepressant as initial treatment in patients in the acute phase of… Continue reading Nonpharmacologic and Pharmacologic Treatments of Adults in the Acute Phase of Major Depressive Disorder: A Living Clinical Guideline From the American College of Physicians
An RCT study showing few weeks of music lessons enhance audio-visual temporal processing
Music involves different senses and is emotional in nature, and musicians show enhanced detection of audio-visual temporal discrepancies and emotion recognition compared to non-musicians. However, whether musical training produces these enhanced abilities or if they are innate within musicians remains unclear. Thirty-one adult participants were randomly assigned to a music training, music listening, or control… Continue reading An RCT study showing few weeks of music lessons enhance audio-visual temporal processing