Background: Bipolar disorder is a chronic psychiatric condition characterized by alternating episodes of mania and depression, and the prediction and management of mood episodes remain significant clinical challenges. Traditional assessments of mood states have largely relied on subjective methods, such as clinical interviews and self-report questionnaires, which present limitations in terms of early detection and… Continue reading #Wearable -derived heart rate variability and sleep monitoring as predictors of #mood episodes in bipolar disorder: a case report
Tag: Bipolar Disorder
Cause-specific excess #mortality after first diagnosis of #bipolar disorder: population-based cohort study
Background Bipolar disorder (BD) is associated with increased mortality, but evidence on cause-specific mortality is limited.Objective To investigate cause-specific premature excess mortality in BD.Methods Finnish nationwide cohort study of individuals with and without a diagnosis of BD who were aged 15–64 years during 2004–2018. Standardised mortality ratios (SMRs) with 95% CIs were calculated for BD using the mortality… Continue reading Cause-specific excess #mortality after first diagnosis of #bipolar disorder: population-based cohort study
Association of Lithium Treatment With the Risk of Osteoporosis in Patients With Bipolar Disorder
Importance Osteoporosis, a systemic skeletal disorder associated with substantial morbidity and mortality, may be particularly common among individuals with bipolar disorder. Lithium, a first-line mood-stabilizing treatment for bipolar disorder, may have bone-protecting properties. Objective To evaluate if treatment with lithium is associated with a decrease in risk of osteoporosis among patients with bipolar disorder. Design,… Continue reading Association of Lithium Treatment With the Risk of Osteoporosis in Patients With Bipolar Disorder
Adjunctive #dietary intervention for #bipolar disorder: a randomized, controlled, parallel-group, modified double-blinded trial of a high n-3 plus low n-6 diet
To investigate the preliminary efficacy of a high n-3 plus low n-6 (H3-L6) dietary intervention in improving mood stability in Bipolar Disorder (BD) when compared to dietary intervention with usual U.S. levels of n-6 and n-3 polyunsaturated fatty acid (PUFA) intakes (control diet, CD). MethodsThis 2-arm, parallel-group, randomized, modified double-blind, controlled 48-week study of 12-week… Continue reading Adjunctive #dietary intervention for #bipolar disorder: a randomized, controlled, parallel-group, modified double-blinded trial of a high n-3 plus low n-6 diet
The impact of #caffeine consumption on clinical symptoms in patients with #bipolar disorder: A systematic review
In healthy populations, caffeine appears to have beneficial effects on health; however, patients with bipolar disorder (BD) are routinely advised to limit caffeine use in psychoeducation programmes. We aimed to examine all literature reporting whether caffeine intake/withdrawal impacts the natural course of BD, in terms of clinical outcomes. MethodsPubMed, Embase and PsycINFO were searched (up… Continue reading The impact of #caffeine consumption on clinical symptoms in patients with #bipolar disorder: A systematic review
#ABCA13 dysfunction associated with #psychiatric disorders causes impaired cholesterol trafficking
ATP-binding cassette subfamily A member 13 (ABCA13) is predicted to be the largest ABC protein, consisting of 5,058 amino acids and a long N-terminal region. Mutations in the ABCA13 gene were reported to increase the susceptibility to schizophrenia, bipolar disorder and major depression. However, little is known about the molecular functions of ABCA13 or how… Continue reading #ABCA13 dysfunction associated with #psychiatric disorders causes impaired cholesterol trafficking
Shared Genetic Loci Between Body #Mass Index and Major #Psychiatric Disorders A Genome-wide Association Study
People with major psychiatric disorders (MPDs) have a 10- to 20-year shorter life span than the rest of the population, and this difference is mainly due to comorbid cardiovascular diseases.. schizophrenia (SCZ), bipolar disorder (BIP), major depression (MD) body mass index (BMI) ..Of the shared loci, 34% (73 of 213) in SCZ, 52% (36 of… Continue reading Shared Genetic Loci Between Body #Mass Index and Major #Psychiatric Disorders A Genome-wide Association Study
Risk of Developing #Parkinson Disease in #Bipolar Disorder A Systematic Review and Meta-analysis
..Seven studies were eligible for inclusion and included 4 374 211 participants overall. A previous diagnosis of BD increased the likelihood of a subsequent diagnosis of idiopathic PD (odds ratio, 3.35; 95% CI, 2.00-5.60; I2 = 92%). A sensitivity analysis was performed by removing the studies that had a high risk of bias and also showed an increased risk… Continue reading Risk of Developing #Parkinson Disease in #Bipolar Disorder A Systematic Review and Meta-analysis
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