To the Editor,On October 2020, Sestili and Fimognari reported that acetaminophen (N-aetyl-para-aminophenol), commonly known as paracetamol, induces or worsens glutathione (GSH) consumption in elderly patients affected by early or mild coronavirus disease 2019 (COVID-19), thus greatly enhancing the risk of COVID-19 exacerbation in these patients.1 By early COVID-19, we mean the typical or commonly acknowledged… Continue reading Paracetamol in the home treatment of early COVID-19 symptoms: A possible foe rather than a friend for elderly patients?
Tag: acetaminophen
Sodium-containing acetaminophen and cardiovascular outcomes in individuals with and without hypertension
AimsPrevious studies have found high sodium intake to be associated with increased risks of cardiovascular disease (CVD) and all-cause mortality among individuals with hypertension; findings on the effect of intake among individuals without hypertension have been equivocal. We aimed to compare the risks of incident CVD and all-cause mortality among initiators of sodium-containing acetaminophen with… Continue reading Sodium-containing acetaminophen and cardiovascular outcomes in individuals with and without hypertension
Paracetamol in the home treatment of early COVID-19 symptoms: A possible foe rather than a friend for elderly patients?
On October 2020, Sestili and Fimognari reported that acetaminophen (N-aetyl-para-aminophenol), commonly known as paracetamol, induces or worsens glutathione (GSH) consumption in elderly patients affected by early or mild coronavirus disease 2019 (COVID-19), thus greatly enhancing the risk of COVID-19 exacerbation in these patients.1 By early COVID-19, we mean the typical or commonly acknowledged symptomatology associated… Continue reading Paracetamol in the home treatment of early COVID-19 symptoms: A possible foe rather than a friend for elderly patients?
Acute #Liver Injury With Therapeutic Doses of #Acetaminophen: A Prospective Study
Because of the extensive use of this drug, further evaluation of acute liver injury (ALI) with therapeutic doses of acetaminophen (APAP; ≤6 g/d) is required. We characterize ALI with therapeutic doses of APAP and determine the host factors associated with disease severity and the predictors of outcome. Approach and Results All patients admitted with severe… Continue reading Acute #Liver Injury With Therapeutic Doses of #Acetaminophen: A Prospective Study
Comparison of #Acetaminophen (Paracetamol) With #Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years
Acetaminophen (paracetamol) and ibuprofen are the most widely prescribed and available over-the-counter medications for management of fever and pain in children. Despite the common use of these medications, treatment recommendations for young children remain divergent.. ..Overall, 19 studies (11 randomized; 8 nonrandomized) of 241 138 participants from 7 countries and various health care settings (hospital-based and… Continue reading Comparison of #Acetaminophen (Paracetamol) With #Ibuprofen for Treatment of Fever or Pain in Children Younger Than 2 Years
2 Medical News 