This brief review was presented here to facilitate an independent and more balanced discussion on the potential risks due to the presence of adenovirus vector DNA (AstraZeneca, Johnson & Johnson, Sputnik V and others) or SARS-CoV-2 RNA (BioNTech/Pfizer, Moderna) in vaccines that are supposed to protect against Covid-19. Of course, injections of vector-based vaccines into… Continue reading Adenoviral Vector DNA- and #SARS-CoV-2 mRNA-Based Covid-19 Vaccines: Possible Integration into the Human #Genome – Are Adenoviral Genes Expressed in Vector-based Vaccines?
The relation between #oxytocin receptor gene polymorphisms, adult attachment and #Instagram sociability: An exploratory analysis
AbstractOxytocin is a primary neuropeptide which coordinates affiliative behavior. Previous researchers pointed to the association between genetic vulnerability on Oxytocin Receptor Gene (OXTR) and environmental factors (e.g., social relationships) to comprehend social behavior. Although an extensive knowledge of in-person social interactions has been obtained, little is known about online sociability. A gene-environment perspective is adopted… Continue reading The relation between #oxytocin receptor gene polymorphisms, adult attachment and #Instagram sociability: An exploratory analysis
A Meta-Analysis on the Global Prevalence, Risk factors and Screening of Coronary #Heart Disease in Non-alcoholic #Fatty Liver Disease
Background and AimsCardiovascular disease remains the leading cause of death in patients with non-alcoholic fatty liver disease (NAFLD). Studies examining the association of coronary heart disease (CHD) and NAFLD are cofounded by various cardiometabolic factors particularly diabetes and body mass index. Hence, we seek to explore such association by investigating the global prevalence, independent risk… Continue reading A Meta-Analysis on the Global Prevalence, Risk factors and Screening of Coronary #Heart Disease in Non-alcoholic #Fatty Liver Disease
Role and Mechanism of Gut #Microbiota in Human #Disease
The human gut microbiome is a huge microbial community that plays an irreplaceable role in human life. With the further development of research, the influence of intestinal flora on human diseases has been gradually excavated. Gut microbiota (GM) dysbiosis has adverse health effects on the human body that will lead to a variety of chronic… Continue reading Role and Mechanism of Gut #Microbiota in Human #Disease
#Obesity treatment: #Weight loss versus increasing #fitness and physical activity for reducing health risks
We propose a weight-neutral strategy for obesity treatment on the following grounds: (1) the mortality risk associated with obesity is largely attenuated or eliminated by moderate-to-high levels of cardiorespiratory fitness (CRF) or physical activity (PA), (2) most cardiometabolic risk markers associated with obesity can be improved with exercise training independent of weight loss and by… Continue reading #Obesity treatment: #Weight loss versus increasing #fitness and physical activity for reducing health risks
Computational drug repositioning of #atorvastatin for ulcerative #colitis
Ulcerative colitis (UC) is a chronic inflammatory disorder with limited effective therapeutic options for long-term treatment and disease maintenance. We hypothesized that a multi-cohort analysis of independent cohorts representing real-world heterogeneity of UC would identify a robust transcriptomic signature to improve identification of FDA-approved drugs that can be repurposed to treat patients with UC. Materials… Continue reading Computational drug repositioning of #atorvastatin for ulcerative #colitis
Baseline #Gut Metagenomic Functional Gene Signature Associated with Variable #Weight Loss Responses following a Healthy Lifestyle Intervention in Humans
Recent human feeding studies have shown how the baseline taxonomic composition of the gut microbiome can determine responses to weight loss interventions. However, the functional determinants underlying this phenomenon remain unclear. We report a weight loss response analysis on a cohort of 105 individuals selected from a larger population enrolled in a commercial wellness program,… Continue reading Baseline #Gut Metagenomic Functional Gene Signature Associated with Variable #Weight Loss Responses following a Healthy Lifestyle Intervention in Humans
Prevalence and Associated Diseases of #Seborrheic Skin in Adults
Seborrhea is a skin condition characterized by abundant production of sebum associated with typical dermatological conditions such as rosacea and acne. Little is known about the prevalence of seborrhea and the frequency of concurrent skin diseases in the general population. Objective: To investigate the epidemiology and comorbidity of seborrhea in the adolescent and adult working… Continue reading Prevalence and Associated Diseases of #Seborrheic Skin in Adults
Analysis of Features of #Alzheimer’s Disease: Detection of Early Stage from Functional Brain Changes in Magnetic #Resonance Images Using a Finetuned ResNet18 Network
One of the first signs of Alzheimer’s disease (AD) is mild cognitive impairment (MCI), in which there are small variants of brain changes among the intermediate stages. Although there has been an increase in research into the diagnosis of AD in its early levels of developments lately, brain changes, and their complexity for functional magnetic… Continue reading Analysis of Features of #Alzheimer’s Disease: Detection of Early Stage from Functional Brain Changes in Magnetic #Resonance Images Using a Finetuned ResNet18 Network
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