PurposeRobot-assisted systems offer an opportunity to support the diagnostic and therapeutic treatment of vascular diseases to reduce radiation exposure and support the limited medical staff in vascular medicine. In the diagnosis and follow-up care of vascular pathologies, Doppler ultrasound has become the preferred diagnostic tool. The study presents a robotic system for automatic Doppler ultrasound… Continue reading Automatic #robotic doppler #sonography of leg #arteries
Timing and combinations of #cardiovascular diseases in survivors of childhood, adolescent, and young adulthood #cancer
Children, adolescents, and young adults with cancer (referred to as CAYAs) are at risk of long-term health complications, with cardiovascular disease (CVD) being a major concern. In addition, sociodemographic characteristics and traditional cardiovascular risk factors may also contribute to disparities in outcomes compared with those of the general population.The aim of this study was to… Continue reading Timing and combinations of #cardiovascular diseases in survivors of childhood, adolescent, and young adulthood #cancer
Short-term association between ambient air #pollution and #heart #rate variability: results from the population-based KORA S4 and FF4 studies
Background: Ambient air pollution is a major risk factor for CVDs, and a plausible mechanism is speculated to be alteration of autonomic nervous system (ANS) function. Yet, the short-term effects of air pollution on heart rate variability (HRV), a measure of ANS balance are inconsistent.Objective: This study aimed to evaluate the short-term effects of ambient… Continue reading Short-term association between ambient air #pollution and #heart #rate variability: results from the population-based KORA S4 and FF4 studies
A New Paradigm to Reduce Cardiovascular #Disease Based on the Pathogenesis of #Atherosclerosis
Atherosclerotic coronary artery disease is the number one cause of morbidity and mortality in the United States, Europe, and Westernized countries. This review recommends a new paradigm for the reduction of atherosclerotic coronary artery disease, namely prevention and treatment by addressing the pathophysiological basis of atherosclerotic disease. This paradigm utilizes the role of cholesterol transport… Continue reading A New Paradigm to Reduce Cardiovascular #Disease Based on the Pathogenesis of #Atherosclerosis
#Cholesterol -lowering drug targets reduce risk of #dementia : Mendelian randomization and meta-analyses of 1 million individuals
We tested whether genetically proxied non-high-density lipoprotein cholesterol (non-HDL-C)–lowering drug targets reduce risk of all-cause dementia.METHODSWe included 1,091,775 individuals from three prospective general population cohorts with individual-level data and two consortia with summary-level data. We selected genetic variants within HMGCR, NPC1L1, PCSK9, ANGPTL4, LPL, and CETP associated with non-HDL-C. These variants were used as exposures… Continue reading #Cholesterol -lowering drug targets reduce risk of #dementia : Mendelian randomization and meta-analyses of 1 million individuals
Slow-Tempo #Music and #Delirium / #Coma -Free Days Among #Older Adults Undergoing Mechanical VentilationA Randomized Clinical Trial
Importance An estimated 70% to 80% of older adults develop delirium in the intensive care unit (ICU).Objective To determine if a slow-tempo music (60-80 beats/min) listening intervention decreases delirium duration, delirium severity, pain, or anxiety in older adults undergoing mechanical ventilation.Design, Setting, and Participants This multicenter randomized clinical trial with concealed outcomes assessments was conducted… Continue reading Slow-Tempo #Music and #Delirium / #Coma -Free Days Among #Older Adults Undergoing Mechanical VentilationA Randomized Clinical Trial
Beyond human ears: navigating the uncharted risks of #AI scribes in clinical #practice
Artificial intelligence (AI) scribes have been rapidly adopted across health systems, driven by their promise to ease the documentation burden and reduce clinician burnout. While early evidence shows efficiency gains, this commentary cautions that adoption is outpacing validation and oversight. Without greater scrutiny, the rush to deploy AI scribes may compromise patient safety, clinical integrity,… Continue reading Beyond human ears: navigating the uncharted risks of #AI scribes in clinical #practice
#Macroeconomic #income inequality, #brain structure and function, and #mental health
Income inequality, a structural property of societies characterized by the unequal distribution of resources, is associated with adverse mental health outcomes during adolescence, which is a sensitive period of neurodevelopment. While previous research has explored the impact of individual-level socioeconomic factors on brain structure and function, the neurobiological mechanisms linking structural inequality to mental health… Continue reading #Macroeconomic #income inequality, #brain structure and function, and #mental health
Identification of five #sleep -biopsychosocial profiles with specific neural signatures linking sleep variability with #health, cognition, and lifestyle factors
Sleep is essential for optimal functioning and health. Interconnected to multiple biological, psychological, and socio-environmental factors (i.e., biopsychosocial factors), the multidimensional nature of sleep is rarely capitalized on in research. Here, we deployed a data-driven approach to identify sleep-biopsychosocial profiles that linked self-reported sleep patterns to inter-individual variability in health, cognition, and lifestyle factors in… Continue reading Identification of five #sleep -biopsychosocial profiles with specific neural signatures linking sleep variability with #health, cognition, and lifestyle factors
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