..Mean ± SD serum testosterone was 435.5 ± 6.7 ng/dl. Mean testosterone was lower among men with a low fat diet (410.8 ± 8.1 vs 443.5 ± 7.3, p=0.005) and a Mediterranean diet (412.9 ± 9.1 vs 443.5 ± 7.3, p=0.002). Multivariable analysis controlling for age, body mass index, activity level, diabetes, comorbidities and prostate… Continue reading The Association between Popular #Diets and Serum #Testosterone among Men in the United States
Category: Endocrinology
Assessing the Risk for #Gout With Sodium–Glucose Cotransporter-2 Inhibitors in Patients With Type 2 Diabetes: A Population-Based Cohort Study
Hyperuricemia is common in patients with type 2 diabetes mellitus and is known to cause gout. Sodium–glucose cotransporter-2 (#SGLT2) inhibitors prevent glucose reabsorption and lower serum uric acid levels.. ..The gout incidence rate was lower among patients prescribed an SGLT2 inhibitor (4.9 events per 1000 person-years) than those prescribed a GLP1 agonist (7.8 events per… Continue reading Assessing the Risk for #Gout With Sodium–Glucose Cotransporter-2 Inhibitors in Patients With Type 2 Diabetes: A Population-Based Cohort Study
Decreasing human body #temperature in the United States since the industrial revolution
In 1851, the German In 1851, the German physician Carl Reinhold August Wunderlich obtained millions of axillary temperatures from 25,000 patients in Leipzig, thereby establishing the standard for normal human body temperature of 37°C or 98.6 °F (range: 36.2–37.5°C [97.2- 99.5 °F]) (Mackowiak, 1997; Wunderlich and Sequin, 1871). A compilation of 27 modern studies, however… Continue reading Decreasing human body #temperature in the United States since the industrial revolution
Hepatic Lipoprotein Export and Remission of Human Type 2 #Diabetes after #Weight Loss
..Liver fat, VLDL1-triglyceride production, and intra-pancreatic fat decreased after weight loss and remained normalized after 24 months of remission. First-phase insulin response remained increased only in those maintaining diabetes remission. Compared with those in remission at 24 months, individuals who relapsed after initial remission had a greater rise in the content of VLDL1-triglyceride and VLDL1-palmitic… Continue reading Hepatic Lipoprotein Export and Remission of Human Type 2 #Diabetes after #Weight Loss
Does type 2 #diabetes confer higher relative rates of #cardiovascular events in women compared with men?
..calculate overall and age-dependent incidence rates, incidence rate ratios, and women-to-men ratios for myocardial infarction, heart failure, ischaemic stroke, or cardiovascular death (MACE-HF). Among 218 549 (46% women) individuals with diabetes, the absolute rate of MACE-HF was higher in men than in women (24.9 vs. 19.9 per 1000 person-years). Corresponding absolute rates in men and… Continue reading Does type 2 #diabetes confer higher relative rates of #cardiovascular events in women compared with men?
The Effect of #Macronutrients on #Reproductive Hormones in Overweight and Obese Men: A Pilot Study
..Hypogonadal obese men find it difficult to lose weight. We investigated whether the modification of macronutrient intake can alter testosterone levels independently of the body mass index. Fasted overweight or obese fertile men were asked to consume meals of polyunsaturated fats (PUFA), monounsaturated fats (MUFA), refined carbohydrates (CHO, orange juice, OJ), whey and egg albumin… Continue reading The Effect of #Macronutrients on #Reproductive Hormones in Overweight and Obese Men: A Pilot Study
#Glycated hemoglobin predicts #coronary artery disease in non-diabetic adults
..All patients underwent coronary computed tomography angiography (CCTA) for evaluation of chest pain. The extent of coronary artery stenosis (CAS) was quantified as percentage for each patient based on plaques detected in CCTA. ..Mean blood pressure of the patients was (91.2 ± 11.9 mmHg), BMI (28.3 ± 5.8 kg/m2), serum cholesterol level (174 ± 33.1 mg/dl), and HbA1c levels (mean 5.7 ± 0.45, median 5.7 and… Continue reading #Glycated hemoglobin predicts #coronary artery disease in non-diabetic adults
#Ultraprocessed Food Consumption and Risk of Type 2 #Diabetes Among Participants of the NutriNet-Santé Prospective Cohort
Ultraprocessed foods (UPF) are widespread in Western diets.. ..Absolute T2D rates in the lowest and highest UPF consumers were 113 and 166 per 100 000 person-years, respectively. Consumption of UPF was associated with a higher risk of T2D (multi-adjusted hazard ratio [HR] for an absolute increment of 10 in the percentage of UPF in the diet,… Continue reading #Ultraprocessed Food Consumption and Risk of Type 2 #Diabetes Among Participants of the NutriNet-Santé Prospective Cohort
#BPA: have flawed analytical techniques compromised risk assessments?
Experimental and epidemiological studies provide compelling evidence of a causal link between increasing exposure to endocrine-disrupting chemicals (environmental contaminants with the potential to perturb the development and function of the endocrine system) and increases in non-communicable diseases, including most aspects of metabolic syndrome.. ..By virtue of extensive research attention, bisphenol A (BPA) has become the… Continue reading #BPA: have flawed analytical techniques compromised risk assessments?
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