A brief #diet intervention can reduce symptoms of #depression in young adults – A randomised controlled trial

There is strong epidemiological evidence that poor diet is associated with depression. The reverse has also been shown, namely that eating a healthy diet rich in fruit, vegetables, fish and lean meat, is associated with reduced risk of depression No such RCTs have been performed in young adults. Young adults with elevated levels of depression… Continue reading A brief #diet intervention can reduce symptoms of #depression in young adults – A randomised controlled trial

Marine #Omega‐3 Supplementation and #Cardiovascular Disease: An Updated Meta‐Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants

In the analysis excluding REDUCE‐IT (Reduction of Cardiovascular Events with Icosapent Ethyl‐Intervention Trial), marine omega‐3 supplementation was associated with significantly lower risk of myocardial infarction (rate ratio [RR] [95% CI]: 0.92 [0.86, 0.99]; P=0.020), CHD death (RR [95% CI]: 0.92 [0.86, 0.98]; P=0.014), total CHD (RR [95% CI]: 0.95 [0.91, 0.99]; P=0.008), CVD death (RR… Continue reading Marine #Omega‐3 Supplementation and #Cardiovascular Disease: An Updated Meta‐Analysis of 13 Randomized Controlled Trials Involving 127 477 Participants

Dietary #Sugars Alter Hepatic #Fatty Acid #Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Highlights • Addition of fructose to a high-fat diet increases hepatic malonyl-CoA more than glucose •Knockdown of the fructose metabolizing gene ketohexokinase increases CTP1a levels •Fructose supplementation alters mitochondrial size and function •Dietary fructose induces acetylation of ACADL and CPT1a to modify fat oxidation In summary, dietary fructose, but not glucose, supplementation of HFD impairs… Continue reading Dietary #Sugars Alter Hepatic #Fatty Acid #Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins

Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia

BMI, alcohol intake, adherence to a DASH‐style diet, and diuretic use were all associated with serum urate levels and the presence of hyperuricemia in a dose‐response manner. The corresponding PARs of hyperuricemia cases for overweight/obesity (prevalence, 60%), non‐adherence to a DASH‐style diet (prevalence, 82%), alcohol use (prevalence, 48%), and diuretic use (prevalence, 8%) were 44%… Continue reading Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia

Healthy Dietary Patterns and Incidence of CKD. A Meta-Analysis of Cohort Studies

Healthy dietary patterns typically encouraged higher intakes of vegetables, fruit, legumes, nuts, whole grains, fish and low-fat dairy, and lower intakes of red and processed meats, sodium, and sugar-sweetened beverages. A healthy dietary pattern was associated with a lower incidence of CKD (odds ratio [OR] 0.70 (95% confidence interval [95% CI], 0.60 to 0.82); I2=51%;… Continue reading Healthy Dietary Patterns and Incidence of CKD. A Meta-Analysis of Cohort Studies