In the past 20 years, a large number of epidemiological studies, randomized controlled trials, and meta-analyses have found an inverse relationship between magnesium intake or serum magnesium and cardiovascular disease, indicating that low magnesium status is associated with hypertension, coronary artery calcification, stroke, ischemic heart disease, atrial fibrillation, heart failure, and cardiac mortality. Controlled metabolic… Continue reading The Role of Dietary #Magnesium in #Cardiovascular Disease
Category: Cardiology
Restrictive versus Liberal #Transfusion in Myocardial #Infarction — A Patient-Level Meta-Analysis
BackgroundClinical guidelines have concluded that there are insufficient data to provide recommendations for the hemoglobin threshold for the use of red cell transfusion in patients with acute myocardial infarction (MI) and anemia. After the recent publication of the Myocardial Infarction and Transfusion (MINT) trial, we performed an individual patient-level data meta-analysis to evaluate the effect… Continue reading Restrictive versus Liberal #Transfusion in Myocardial #Infarction — A Patient-Level Meta-Analysis
Urinary #tartaric acid as a biomarker of #wine consumption and #cardiovascular risk: the PREDIMED trial
Background and AimsModerate wine consumption has been associated with lower cardiovascular disease (CVD) risk in older populations. However, wine consumption information through self-reports is prone to measurement errors inherent to subjective assessments. The aim of this study was to evaluate the association between urinary tartaric acid, an objective biomarker of wine consumption, and the rate… Continue reading Urinary #tartaric acid as a biomarker of #wine consumption and #cardiovascular risk: the PREDIMED trial
Long-Term #Aspirin vs #Clopidogrel After #Coronary Stenting by Bleeding Risk and Procedural Complexity
Question What is the comparative effectiveness of clopidogrel vs aspirin monotherapy in the chronic maintenance period after percutaneous coronary intervention (PCI) according to bleeding risk and procedural complexity?Findings In this post hoc analysis of the HOST-EXAM Extended clinical trial, clopidogrel monotherapy was associated with a reduction in thrombotic and bleeding risks compared with aspirin, regardless… Continue reading Long-Term #Aspirin vs #Clopidogrel After #Coronary Stenting by Bleeding Risk and Procedural Complexity
Device-measured vigorous intermittent lifestyle #physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences
Background Vigorous intermittent lifestyle physical activity (VILPA) refers to brief bouts of intense physical activity embedded into daily life.Objective To examine sex differences in the dose–response association of VILPA with major adverse cardiovascular events (MACE) and its subtypes.Methods Using multivariable-adjusted cubic splines, we examined the associations of daily VILPA duration with overall MACE and its… Continue reading Device-measured vigorous intermittent lifestyle #physical activity (VILPA) and major adverse cardiovascular events: evidence of sex differences
Added #sugar intake and its associations with incidence of seven different #cardiovascular diseases in 69,705 Swedish men and women
Introduction: The adverse health effects of sugar-sweetened beverage intake are well-established, but the implications of overall added sugar intake remain unclear. We investigated the associations between intake of added sugar and various sugar-sweetened foods and beverages and risk of 7 cardiovascular diseases in 69,705 participants aged 45–83 years (47.2% female) from the Swedish Mammography cohort… Continue reading Added #sugar intake and its associations with incidence of seven different #cardiovascular diseases in 69,705 Swedish men and women
Use of common #cardiovascular disease drugs and risk of #dementia: A case–control study in Swedish national register data
Cardiovascular drug use may help prevent dementia; however, current evidence is mixed. Using a case–control design, we investigated the association between duration and combination of multiple cardiovascular drug classes and incident dementia.METHODSFrom the Swedish national registers, we included 88,065 incident dementia cases aged ≥ 70 at diagnosis between 2011 and 2016 and 880,650 age- and… Continue reading Use of common #cardiovascular disease drugs and risk of #dementia: A case–control study in Swedish national register data
#Cardiovascular risk and #obesity impact loss of grey matter volume earlier in males than females
Background It remains imperative to discover the time course that cardiovascular risk factors influence neurodegeneration in males and females and decipher whether the apolipoprotein (APOE) genotype mediates this relationship. Here we perform a large-scale evaluation of the influence of cardiovascular risk and obesity on brain volume in males and females in different age groups.Methods 34… Continue reading #Cardiovascular risk and #obesity impact loss of grey matter volume earlier in males than females
Non-fermented and fermented #milk intake in relation to risk of ischemic #heart disease and to circulating cardiometabolic proteins in swedish women and men: Two prospective longitudinal cohort studies with 100,775 participants
BackgroundThe effect of milk on the risk of ischemic heart disease (IHD) and acute myocardial infarction (MI) is unclear. We aimed to examine the association between non-fermented and fermented milk consumption on these endpoints and investigate the relationship between milk intake and cardiometabolic-related proteins in plasma.MethodsOur study is based on two Swedish prospective cohort studies… Continue reading Non-fermented and fermented #milk intake in relation to risk of ischemic #heart disease and to circulating cardiometabolic proteins in swedish women and men: Two prospective longitudinal cohort studies with 100,775 participants
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