Patterns of diurnal activity differ substantially between individuals, with early risers and late sleepers being examples of opposite chronotypes. Growing evidence suggests that the late chronotype significantly impacts the risk of developing mood disorders, obesity, diabetes, and other chronic diseases. Despite the vast potential of utilizing chronotype information for precision medicine, those factors that shape… Continue reading Metagenomic analysis reveals the signature of gut microbiota associated with human chronotypes
Tag: sleep
Accelerometer-derived sleep onset timing and cardiovascular disease incidence: a UK Biobank cohort study
Growing evidence suggests that poor sleep health is associated with cardiovascular risk. However, research in this area often relies upon recollection dependent questionnaires or diaries. Accelerometers provide an alternative tool for measuring sleep parameters objectively. This study examines the association between wrist-worn accelerometer-derived sleep onset timing and cardiovascular disease (CVD). Methods and resultsWe derived sleep… Continue reading Accelerometer-derived sleep onset timing and cardiovascular disease incidence: a UK Biobank cohort study
Digging for data: How #sleep is losing out to roster design, sleep disorders, and lifestyle factors
Highlights•Shift start times <06:00, may result in sleep loss resulting in poor alertness. •Risk of sleep disorders increased with body mass and age. •Prevalence of shiftwork disorder and obstructive sleep apnea in mining is high. •Biomathematical modeling may be used to eliminate or reduce organizational risk. AbstractShift workers employed at a remote mining operation may… Continue reading Digging for data: How #sleep is losing out to roster design, sleep disorders, and lifestyle factors
Association of accelerometer-derived #sleep measures with lifetime #psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank
Sleep problems are both symptoms of and modifiable risk factors for many psychiatric disorders. Wrist-worn accelerometers enable objective measurement of sleep at scale. Here, we aimed to examine the association of accelerometer-derived sleep measures with psychiatric diagnoses and polygenic risk scores in a large community-based cohort. Methods and findingsIn this post hoc cross-sectional analysis of… Continue reading Association of accelerometer-derived #sleep measures with lifetime #psychiatric diagnoses: A cross-sectional study of 89,205 participants from the UK Biobank
Total #sleep deprivation reduces top-down regulation of #emotion without altering bottom-up affective processing
Sleep loss is reported to influence affective processing, causing changes in overall mood and altering emotion regulation. These aspects of affective processing are seldom investigated together, making it difficult to determine whether total sleep deprivation has a global effect on how affective stimuli and emotions are processed, or whether specific components of affective processing are… Continue reading Total #sleep deprivation reduces top-down regulation of #emotion without altering bottom-up affective processing
Observing changes in human functioning during induced #sleep deficiency and recovery periods
Prolonged periods of sleep restriction seem to be common in the contemporary world. Sleep loss causes perturbations of circadian rhythmicity and degradation of waking alertness as reflected in attention, cognitive efficiency and memory. Understanding whether and how the human brain recovers from chronic sleep loss is important not only from a scientific but also from… Continue reading Observing changes in human functioning during induced #sleep deficiency and recovery periods
#Metabolic responses to polychromatic #LED and #OLED light at night
Light exposure at night has various implications for human health, but little is known about its effects on energy metabolism during subsequent sleep. We investigated the effects of polychromatic white light using conventional light-emitting diodes (LED) and an alternative light source, organic light-emitting diodes (OLED), producing reduced spectral content in the short wavelength of blue… Continue reading #Metabolic responses to polychromatic #LED and #OLED light at night
Bedtime #Music, Involuntary Musical Imagery, and #Sleep
Many people listen to music for hours every day, often near bedtime. We investigated whether music listening affects sleep, focusing on a rarely explored mechanism: involuntary musical imagery (earworms). In Study 1 (N = 199, mean age = 35.9 years), individuals who frequently listen to music reported persistent nighttime earworms, which were associated with worse… Continue reading Bedtime #Music, Involuntary Musical Imagery, and #Sleep
Reduced coupling between cerebrospinal fluid flow and global #brain activity is linked to #Alzheimer disease–related pathology
The glymphatic system plays an important role in clearing the amyloid-β (Aβ) and tau proteins that are closely linked to Alzheimer disease (AD) pathology. Glymphatic clearance, as well as Aβ accumulation, is highly dependent on sleep, but the sleep-dependent driving forces behind cerebrospinal fluid (CSF) movements essential to the glymphatic flux remain largely unclear. Recent… Continue reading Reduced coupling between cerebrospinal fluid flow and global #brain activity is linked to #Alzheimer disease–related pathology
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