Suboptimal sleep durations and depression frequently cooccur. Short-sleep and long-sleep are commonly thought of as symptoms of depression, but a growing literature suggests that they may be prodromal. While each represents a process of mutual influence, the directionality between them remains unclear. Using polygenic scores (PGS), we investigate the prospective direction involved in suboptimal sleep… Continue reading Polygenic predisposition, #sleep duration, and #depression: evidence from a prospective population-based cohort
Tag: depression
#Antidepressants or #running therapy: Comparing effects on mental and physical health in patients with #depression and #anxiety disorders
Highlights•141 patients with depression and/or anxiety disorder participated in this study.•Running therapy and antidepressant medication had similar effects on mental health (remission and response rates).•Running therapy outperformed antidepressant medication on physical health variables.•Running therapy is a valuable treatment strategy in mental health care. BackgroundAntidepressant medication and running therapy are both effective treatments for patients with depressive and anxiety… Continue reading #Antidepressants or #running therapy: Comparing effects on mental and physical health in patients with #depression and #anxiety disorders
High #ultra-processed food consumption is associated with elevated #psychological distress as an indicator of #depression in adults from the Melbourne Collaborative Cohort Study
Highlights•Participants with the highest intake of ultra-processed food had increased odds of elevated psychological distress•We found no evidence for an interaction of sex, age and body mass index with ultra-processed food intake•Further research is needed to better inform nutrition-related and public health strategies for mental health BackgroundFew studies have tested longitudinal associations between ultra-processed food… Continue reading High #ultra-processed food consumption is associated with elevated #psychological distress as an indicator of #depression in adults from the Melbourne Collaborative Cohort Study
#Depression, #anxiety, and the risk of #cancer: An individual participant data meta-analysis
Depression and anxiety have long been hypothesized to be related to an increased cancer risk. Despite the great amount of research that has been conducted, findings are inconclusive. To provide a stronger basis for addressing the associations between depression, anxiety, and the incidence of various cancer types (overall, breast, lung, prostate, colorectal, alcohol-related, and smoking-related… Continue reading #Depression, #anxiety, and the risk of #cancer: An individual participant data meta-analysis
BETTER THAN WE THINK: IS THE TREATMENT OF #DEPRESSED PATIENTS MORE EFFECTIVE THAN WE THINK?
Most studies of depression treatment rely on measures of symptom severity to evaluate outcome. We hypothesized that many patients would consider themselves to have benefitted significantly from treatment despite not being considered a responder according to a measure of depression symptom severity (ie, 50% reduction in symptom score).METHODS: In our study, 854 patients with major depressive… Continue reading BETTER THAN WE THINK: IS THE TREATMENT OF #DEPRESSED PATIENTS MORE EFFECTIVE THAN WE THINK?
The influence of emotion regulation strategies and sleep quality on depression and anxiety
Chronic stress is a major risk factor for a number of mental health disorders, including depression and pathological anxiety. Adaptive cognitive emotion regulation (CER) strategies (i.e. positively-focused thought processes) can help to prevent psychiatric disturbance when enduring unpleasant and stressful experiences, but little is known about the inter-individual factors that govern their success. Sleep plays an important… Continue reading The influence of emotion regulation strategies and sleep quality on depression and anxiety
Physical Activity Dose and Depression in a Cohort of Older Adults in The Irish Longitudinal Study on Ageing
Importance Among older adults (aged ≥50 years), depression is associated with an increased risk of physical, social, and cognitive dysfunction. Regular moderate to vigorous physical activity (MVPA) has been associated with lower odds of depression. However, the lowest dose for protection against depression and the extent to which exceeding this level conveys additional protection are unknown.Objective To… Continue reading Physical Activity Dose and Depression in a Cohort of Older Adults in The Irish Longitudinal Study on Ageing
The associations of glycosylated hemoglobin with grey matter volume and depression: Investigating mediating role of grey matter volume
Highlights•This is the first study to investigate the mediation effect of GMV on the association between HbA1c and depression.•Hba1c was negatively associated with GMV, and that association were stronger in prediabetic participants.•Cerebral GMV plays a mediating role on the association “HbA1c-depression”, with a proportions of 6.82%.•Effective control of glycemia can potentially prevent brain abnormality and… Continue reading The associations of glycosylated hemoglobin with grey matter volume and depression: Investigating mediating role of grey matter volume
Acceptability, Tolerability, and Estimates of Putative Treatment Effects of Probiotics as Adjunctive Treatment in Patients With Depression
The microbiota-gut-brain axis is a promising target for novel treatments for mood disorders, such as probiotics. However, few clinical trials have been conducted, and further safety and efficacy data are needed to support this treatment approach.Objective To provide acceptability and tolerability data and estimates of intervention effect size for probiotics as adjunctive treatment for patients with… Continue reading Acceptability, Tolerability, and Estimates of Putative Treatment Effects of Probiotics as Adjunctive Treatment in Patients With Depression
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