#COVID-19 Pandemic: A Wake-Up Call for Clean #Air

..Since its identification in Wuhan, China, coronavirus disease 2019 (COVID-19) has infected more than 104 million and killed over 2.2 million people worldwide (1). Recent studies of air pollution and COVID-19 cases and mortality in diverse international settings add convincingly to a large body of evidence showing that exposure to air pollution exacerbates viral respiratory… Continue reading #COVID-19 Pandemic: A Wake-Up Call for Clean #Air

The #COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal #Antibodies for the Treatment of COVID-19

The COVID-19 Treatment Guidelines Panel (the Panel) recommends using one of the following combination anti-SARS-CoV-2 monoclonal antibodies to treat outpatients with mild to moderate COVID-19 who are at high risk of clinical progression, as defined by the Emergency Use Authorization (EUA) criteria (listed in alphabetical order): Bamlanivimab 700 mg plus etesevimab 1,400 mg (AIIa); or… Continue reading The #COVID-19 Treatment Guidelines Panel’s Statement on the Emergency Use Authorization of Anti-SARS-CoV-2 Monoclonal #Antibodies for the Treatment of COVID-19

6-month neurological and #psychiatric outcomes in 236 379 survivors of #COVID-19: a retrospective cohort study using electronic health records

Summary Background Neurological and psychiatric sequelae of COVID-19 have been reported, but more data are needed to adequately assess the effects of COVID-19 on brain health. We aimed to provide robust estimates of incidence rates and relative risks of neurological and psychiatric diagnoses in patients in the 6 months following a COVID-19 diagnosis. Methods For… Continue reading 6-month neurological and #psychiatric outcomes in 236 379 survivors of #COVID-19: a retrospective cohort study using electronic health records

Association of Vitamin #D Levels, Race/Ethnicity, and Clinical Characteristics With #COVID-19 Test Results

Deficient (ie, <20 ng/mL) or insufficient (ie, 20 to <30 ng/mL) 25-hydroxyvitamin D (also known as calcifediol) levels are more common in Black individuals than White individuals and are associated with increased coronavirus disease 2019 (COVID-19) risk. Whether COVID-19 risk is associated with differences in vitamin D levels of 30 ng/mL or greater is not… Continue reading Association of Vitamin #D Levels, Race/Ethnicity, and Clinical Characteristics With #COVID-19 Test Results

Online #Mindfulness May Target Psychological #Distress and Mental Health during #COVID-19

The COVID-19 pandemic has dramatically affected mental health, creating an urgent need for convenient and safe interventions to improve well-being. Online mindfulness interventions show promise for improving depression, anxiety, and general well-being. Objective To assess: 1) the impact of online mindfulness on psychological distress, 2) altruistic efforts, and 3) the quantity, quality, and availability of… Continue reading Online #Mindfulness May Target Psychological #Distress and Mental Health during #COVID-19

#Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With #Coronavirus Disease 2019

Coronavirus disease-2019 (COVID-19) is associated with hypercoagulability and increased thrombotic risk in critically ill patients. To our knowledge, no studies have evaluated whether aspirin use is associated with reduced risk of mechanical ventilation, intensive care unit (ICU) admission, and in-hospital mortality. METHODS: A retrospective, observational cohort study of adult patients admitted with COVID-19 to multiple… Continue reading #Aspirin Use Is Associated With Decreased Mechanical Ventilation, Intensive Care Unit Admission, and In-Hospital Mortality in Hospitalized Patients With #Coronavirus Disease 2019

Circulating Vitamin #D levels status and clinical prognostic indices in #COVID-19 patients

Several immune mechanisms activate in COVID-19 pathogenesis. Usually, coronavirus infection is characterized by dysregulated host immune responses, interleukine-6 increase, hyper-activation of cytotoxic CD8 T lymphocytes. Interestingly, Vitamin D deficiency has been often associated with altered immune responses and infections. In the present study, we evaluated Vitamin D plasma levels in patients affected with different lung… Continue reading Circulating Vitamin #D levels status and clinical prognostic indices in #COVID-19 patients

Assessment of protection against #reinfection with #SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study

The degree to which infection with SARS-CoV-2 confers protection towards subsequent reinfection is not well described. In 2020, as part of Denmark's extensive, free-of-charge PCR-testing strategy, approximately 4 million individuals (69% of the population) underwent 10·6 million tests. Using these national PCR-test data from 2020, we estimated protection towards repeat infection with SARS-CoV-2. Methods In… Continue reading Assessment of protection against #reinfection with #SARS-CoV-2 among 4 million PCR-tested individuals in Denmark in 2020: a population-level observational study

Impact of the #COVID-19 Vaccine on Asymptomatic #Infection Among Patients Undergoing Pre-Procedural COVID-19 Molecular Screening

Several vaccines are now clinically available under emergency use authorization in the United States and have demonstrated efficacy against symptomatic COVID-19. The impact of vaccines on asymptomatic SARS-CoV-2 infection is largely unknown. Methods We conducted a retrospective cohort study of consecutive, asymptomatic adult patients (n = 39,156) within a large United States healthcare system who… Continue reading Impact of the #COVID-19 Vaccine on Asymptomatic #Infection Among Patients Undergoing Pre-Procedural COVID-19 Molecular Screening