AbstractBackground: While hydration is currently the most evidence-supported strategy for preventing contrast-associated acute kidney injury (CA-AKI) in patients undergoing cardiovascular angiography, the potential benefits of combining a saline and N-acetylcysteine (NAC) based strategy with additional pharmacologic interventions remain uncertain.Methods: We conducted a search for randomized controlled trials (RCTs) in PubMed, Embase, and the Cochrane library… Continue reading Saline and #N-acetylcysteine based strategies and other approaches to prevent the risk of CA- #AKI: a meta-analysis
Tag: AKI
Acute #Kidney Injury and Its Association With #Dementia and Specific Dementia Types
Background and ObjectivesPreclinical studies suggest that acute kidney injury (AKI) results in biochemical and pathologic changes in the brain. We aimed to explore the association between experiencing AKI and subsequent risks of developing dementia.MethodsWe conducted a study involving individuals aged 65 years and older in Stockholm from 2006 to 2019, who were free from dementia… Continue reading Acute #Kidney Injury and Its Association With #Dementia and Specific Dementia Types
Detecting Severe #AKI in Hospitalized Patients with Biomarkers of Kidney Injury – A Physician’s Guide to Precision Diagnosis
Acute Kidney Injury (AKI) is a critical concern in hospitalized patients, associated with increased morbidity, mortality, and healthcare costs. The ability to detect AKI early and accurately is paramount for timely intervention and improved patient outcomes. In this post, I embark on a physician’s journey to explore the world of biomarkers for kidney injury, shedding… Continue reading Detecting Severe #AKI in Hospitalized Patients with Biomarkers of Kidney Injury – A Physician’s Guide to Precision Diagnosis
Longitudinal biomarkers and kidney disease progression after acute kidney injury
BACKGROUND. Longitudinal investigations of murine acute kidney injury (AKI) suggest that injury and inflammation may persist long after the initial insult. However, the evolution of these processes and their prognostic values are unknown in patients with AKI.METHODS. In a prospective cohort of 656 participants hospitalized with AKI, we measured 7 urine and 2 plasma biomarkers of kidney… Continue reading Longitudinal biomarkers and kidney disease progression after acute kidney injury
Coffee Consumption May Mitigate the Risk for Acute Kidney Injury: Results From the Atherosclerosis Risk in Communities Study
Coffee is one of the most frequently consumed beverages worldwide and has been found to have a wide assortment of health benefits. Although habitual coffee consumption is associated with a lower incidence of chronic kidney disease, an association between coffee and acute kidney injury (AKI) has not yet been revealed.MethodsIn the Atherosclerosis Risk in Communities… Continue reading Coffee Consumption May Mitigate the Risk for Acute Kidney Injury: Results From the Atherosclerosis Risk in Communities Study
Diagnosis-wide analysis of #COVID-19 complications: an exposure-crossover study
Many studies reporting coronavirus disease 2019 (COVID-19) complications have involved case series or small cohorts that could not establish a causal association with COVID-19 or provide risk estimates in different care settings. We sought to study all possible complications of COVID-19 to confirm previously reported complications and to identify potential complications not yet known.. ..Among… Continue reading Diagnosis-wide analysis of #COVID-19 complications: an exposure-crossover study
#Hypoalbuminemia is associated with increased risk of acute #kidney injury in hospitalized patients: A meta-analysis
Highlights • Each 1.0 g/dL of serum albumin decrement was associated with increased odds of AKI (OR 1.685; 95% CI, 1.302–2.179). • The risk factors for AKI in hypoalbuminemic patients include 1) age ≥ 70 years and 2) baseline serum albumin level > 3.2 g/dL. • The association between hypoalbuminemia and overall mortality from AKI remained inconclusive as there was potential publication… Continue reading #Hypoalbuminemia is associated with increased risk of acute #kidney injury in hospitalized patients: A meta-analysis
Natural history of acute #kidney disease in patients with #cirrhosis
In 2012, KDIGO group proposed new definitions for Acute Kidney Injury (AKI), Acute Kidney Disease (AKD) and Chronic Kidney Disease (CKD). According to the definition adapted by the International Club of Ascites (ICA), AKI has been extensively investigated in patients with cirrhosis. On the contrary, there are currently no data on the epidemiology and clinical… Continue reading Natural history of acute #kidney disease in patients with #cirrhosis
ACUTE #KIDNEY INJURY IN PATIENTS HOSPITALIZED WITH #COVID-19
The rate of acute kidney injury (AKI) associated with patients hospitalized with Covid-19, and associated outcomes are not well understood. This study describes the presentation, risk factors and outcomes of AKI in patients hospitalized with Covid-19. We reviewed the health records for all patients hospitalized with Covid-19 between March 1, and April 5, 2020, at… Continue reading ACUTE #KIDNEY INJURY IN PATIENTS HOSPITALIZED WITH #COVID-19
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