Here, the authors report on the manufacturing and in vivo assessment of a bioresorbable nanostructured pH sensor. The sensor consists of a micrometer-thick porous silica membrane conformably coated layer-by-layer with a nanometer-thick multilayer stack of two polyelectrolytes labeled with a pH-insensitive fluorophore. The sensor fluorescence changes linearly with the pH value in the range 4… Continue reading Bioresorbable Nanostructured Chemical Sensor for Monitoring of pH Level In Vivo
Category: Tech
Antibody–Invertase Fusion Protein Enables Quantitative Detection of SARS-CoV-2 Antibodies Using Widely Available Glucometers
Rapid diagnostics that can accurately inform patients of disease risk and protection are critical to mitigating the spread of the current COVID-19 pandemic and future infectious disease outbreaks. To be effective, such diagnostics must rely on simple, cost-effective, and widely available equipment and should be compatible with existing telehealth infrastructure to facilitate data access and… Continue reading Antibody–Invertase Fusion Protein Enables Quantitative Detection of SARS-CoV-2 Antibodies Using Widely Available Glucometers
Smartphone use undermines enjoyment of face-to-face social interactions
Using a field experiment and experience sampling, we found the first evidence that phone use may undermine the enjoyment people derive from real world social interactions. In Study 1, we recruited over 300 community members and students to share a meal at a restaurant with friends or family. Participants were randomly assigned to keep their… Continue reading Smartphone use undermines enjoyment of face-to-face social interactions
The illusion of evidence based medicine
Evidence based medicine has been corrupted by corporate interests, failed regulation, and commercialisation of academia, argue these authors The advent of evidence based medicine was a paradigm shift intended to provide a solid scientific foundation for medicine. The validity of this new paradigm, however, depends on reliable data from clinical trials, most of which are… Continue reading The illusion of evidence based medicine
‘The Corpse Bride Diet’: How TikTok Inundates Teens With Eating-Disorder Videos
The app’s algorithm can send users down rabbit holes of narrow interest, resulting in potentially dangerous content such as emaciated images, purging techniques, hazardous diets and body shamingBy Tawnell D. Hobbs, Rob Barry and Yoree KohDec. 17, 2021 10:45 am ET TikTok is flooding teen users with videos of rapid-weight-loss competitions and ways to purge… Continue reading ‘The Corpse Bride Diet’: How TikTok Inundates Teens With Eating-Disorder Videos
Digital Interventions for the Treatment of Depression:A Meta-Analytic Review
The high global prevalence of depression, together with the recent acceleration of remote care owingto the COVID-19 pandemic, has prompted increased interest in the efficacy of digital interventions forthe treatment of depression. We provide a summary of the latest evidence base for digital interventionsin the treatment of depression based on the largest study sample to… Continue reading Digital Interventions for the Treatment of Depression:A Meta-Analytic Review
Variation in common laboratory test results caused by ambient temperature
Highlights•Analysis of a dataset of nearly 5 million and over 200 million laboratory test results •Ambient temperature on the day an individual’s blood was drawn affected the test result •Affected assays included renal function tests, complete blood count, and lipid panels •Doctors prescribed fewer statins to individuals whose lipids were checked on colder days. Context… Continue reading Variation in common laboratory test results caused by ambient temperature
Comparing Video-Based, Telehealth-Delivered Exercise and Weight Loss Programs With Online Education on Outcomes of Knee Osteoarthritis
Scalable knee osteoarthritis programs are needed to deliver recommended education, exercise, and weight loss interventions. Objective:To evaluate two 6-month, telehealth-delivered exercise programs, 1 with and 1 without dietary intervention. Design:3-group, parallel randomized (5:5:2) trial. (Australian New Zealand Clinical Trials Registry: ACTRN12618000930280) Setting:Australian private health insurance members. Participants:415 persons with symptomatic knee osteoarthritis and a body… Continue reading Comparing Video-Based, Telehealth-Delivered Exercise and Weight Loss Programs With Online Education on Outcomes of Knee Osteoarthritis
#GLUT4-overexpressing engineered muscle constructs as a therapeutic platform to normalize #glycemia in diabetic mice
Skeletal muscle insulin resistance is a main defect in type 2 diabetes (T2D), which is associated with impaired function and content of glucose transporter type 4 (GLUT4). GLUT4 overexpression in skeletal muscle tissue can improve glucose homeostasis. Therefore, we created an engineered muscle construct (EMC) composed of GLUT4-overexpressing (OEG4) cells. The ability of the engineered… Continue reading #GLUT4-overexpressing engineered muscle constructs as a therapeutic platform to normalize #glycemia in diabetic mice
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