Evidence based medicine has been corrupted by corporate interests, failed regulation, and commercialisation of academia, argue these authors The advent of evidence based medicine was a paradigm shift intended to provide a solid scientific foundation for medicine. The validity of this new paradigm, however, depends on reliable data from clinical trials, most of which are… Continue reading The illusion of evidence based medicine
Category: Tech
‘The Corpse Bride Diet’: How TikTok Inundates Teens With Eating-Disorder Videos
The app’s algorithm can send users down rabbit holes of narrow interest, resulting in potentially dangerous content such as emaciated images, purging techniques, hazardous diets and body shamingBy Tawnell D. Hobbs, Rob Barry and Yoree KohDec. 17, 2021 10:45 am ET TikTok is flooding teen users with videos of rapid-weight-loss competitions and ways to purge… Continue reading ‘The Corpse Bride Diet’: How TikTok Inundates Teens With Eating-Disorder Videos
Digital Interventions for the Treatment of Depression:A Meta-Analytic Review
The high global prevalence of depression, together with the recent acceleration of remote care owingto the COVID-19 pandemic, has prompted increased interest in the efficacy of digital interventions forthe treatment of depression. We provide a summary of the latest evidence base for digital interventionsin the treatment of depression based on the largest study sample to… Continue reading Digital Interventions for the Treatment of Depression:A Meta-Analytic Review
Variation in common laboratory test results caused by ambient temperature
Highlights•Analysis of a dataset of nearly 5 million and over 200 million laboratory test results •Ambient temperature on the day an individual’s blood was drawn affected the test result •Affected assays included renal function tests, complete blood count, and lipid panels •Doctors prescribed fewer statins to individuals whose lipids were checked on colder days. Context… Continue reading Variation in common laboratory test results caused by ambient temperature
Comparing Video-Based, Telehealth-Delivered Exercise and Weight Loss Programs With Online Education on Outcomes of Knee Osteoarthritis
Scalable knee osteoarthritis programs are needed to deliver recommended education, exercise, and weight loss interventions. Objective:To evaluate two 6-month, telehealth-delivered exercise programs, 1 with and 1 without dietary intervention. Design:3-group, parallel randomized (5:5:2) trial. (Australian New Zealand Clinical Trials Registry: ACTRN12618000930280) Setting:Australian private health insurance members. Participants:415 persons with symptomatic knee osteoarthritis and a body… Continue reading Comparing Video-Based, Telehealth-Delivered Exercise and Weight Loss Programs With Online Education on Outcomes of Knee Osteoarthritis
#GLUT4-overexpressing engineered muscle constructs as a therapeutic platform to normalize #glycemia in diabetic mice
Skeletal muscle insulin resistance is a main defect in type 2 diabetes (T2D), which is associated with impaired function and content of glucose transporter type 4 (GLUT4). GLUT4 overexpression in skeletal muscle tissue can improve glucose homeostasis. Therefore, we created an engineered muscle construct (EMC) composed of GLUT4-overexpressing (OEG4) cells. The ability of the engineered… Continue reading #GLUT4-overexpressing engineered muscle constructs as a therapeutic platform to normalize #glycemia in diabetic mice
A “Proof of Concept” Randomized Controlled Trial of a Video Game Requiring Emotional Regulation to Augment #Anger Control Training
Emotional dysregulation leading to clinically significant anger and aggression is a common and substantial concern for youth and their families. While psychotropic medications and cognitive behavioral therapies can be effective, these modalities suffer from drawbacks such as significant side effects, high rates of attrition, and lack of real-world skill translation. Regulate and Gain Emotional Control… Continue reading A “Proof of Concept” Randomized Controlled Trial of a Video Game Requiring Emotional Regulation to Augment #Anger Control Training
The relation between #oxytocin receptor gene polymorphisms, adult attachment and #Instagram sociability: An exploratory analysis
AbstractOxytocin is a primary neuropeptide which coordinates affiliative behavior. Previous researchers pointed to the association between genetic vulnerability on Oxytocin Receptor Gene (OXTR) and environmental factors (e.g., social relationships) to comprehend social behavior. Although an extensive knowledge of in-person social interactions has been obtained, little is known about online sociability. A gene-environment perspective is adopted… Continue reading The relation between #oxytocin receptor gene polymorphisms, adult attachment and #Instagram sociability: An exploratory analysis
#Screen time and early adolescent #mental health, academic, and social outcomes in 9- and 10- year old children: Utilizing the Adolescent Brain #Cognitive Development ℠ (ABCD) Study
In a technology-driven society, screens are being used more than ever. The high rate of electronic media use among children and adolescents begs the question: is screen time harming our youth? The current study draws from a nationwide sample of 11,875 participants in the United States, aged 9 to 10 years, from the Adolescent Brain… Continue reading #Screen time and early adolescent #mental health, academic, and social outcomes in 9- and 10- year old children: Utilizing the Adolescent Brain #Cognitive Development ℠ (ABCD) Study
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