BackgroundAromatase inhibitor-induced arthralgia (AIA) is a frequent adverse effect of endocrine therapy in breast cancer survivors, often leading to treatment modification or discontinuation. Non-pharmacological interventions have been proposed to manage AIA, but evidence remains fragmented.ObjectiveTo synthesize recent randomized controlled trials (RCTs) evaluating the efficacy of non-pharmacological interventions for AIA.MethodsA systematic search of PubMed, Scopus, and… Continue reading Effectiveness of Non-Pharmacological Interventions for Hormone Therapy-Induced #Hand #Arthralgia in Breast Cancer Patients: A Systematic Review
Category: Pain
Pain management in the perioperative orthogeriatric setting: Recommendations of the special interest group Orthogeriatrics of the German Geriatrics Society
Management of perioperative pain in older adults can be challenging. Multimorbidity, functional decline or diminished physiological reserves, the corresponding polypharmacy, age-related pharmacodynamic and pharmacokinetic changes need to be considered. #Pain assessment can be complicated by cognitive impairment and communication barriers. Older adults are at high risk of adverse consequences from surgery and undertreated pain as… Continue reading Pain management in the perioperative orthogeriatric setting: Recommendations of the special interest group Orthogeriatrics of the German Geriatrics Society
Cost-Effectiveness of #Acupuncture Needling for Older Adults With Chronic Low #Back Pain
Preplanned economic evaluation alongside a clinical trial.Objective. Determine the 1-year cost-effectiveness from health care sector and Medicare perspectives of adding either standard #acupuncture (SA; ≤15 treatment sessions over 12 wk) or enhanced acupuncture (EA; SA plus ≤ 6 additional sessions) to usual medical care (UMC) versus UMC alone.Summary of Background Data. Chronic low back #pain… Continue reading Cost-Effectiveness of #Acupuncture Needling for Older Adults With Chronic Low #Back Pain
Effect of core stabilization exercises on #lumbar multifidus morphology and functional outcomes in chronic non-specific low #back pain: a randomized controlled trial
Background: Chronic non-specific low back pain (CNSLBP) is often associated with morphological changes in the lumbar multifidus muscle (LMF), such as reduced cross-sectional area (CSA) and increased fat infiltration, compromising spinal stability and function. Core stabilization exercises aim to enhance neuromuscular control by targeting deep trunk muscles. However, few randomized trials have investigated their effects… Continue reading Effect of core stabilization exercises on #lumbar multifidus morphology and functional outcomes in chronic non-specific low #back pain: a randomized controlled trial
ReviewPractical guidance for navigating #buprenorphine discontinuation
Approximately 4.8 million people in the United States had opioid use disorder in 2024, with more than one hundred thousand experiencing an overdose death. Despite the established benefits of buprenorphine on morbidity and mortality, many patients may express an interest in discontinuing their medications for various reasons, including stigma surrounding addiction. There are limited studies… Continue reading ReviewPractical guidance for navigating #buprenorphine discontinuation
[Thermo- #electroacupuncture at #yaosanzhen for chronic #lumbar #muscle strain of cold dampness: a randomized controlled trial]
Objective: To compare the clinical efficacy between thermo-electroacupuncture at yaosanzhen and oral celecoxib in the treatment of chronic lumbar muscle strain with cold dampness.Methods: A total of 80 patients with chronic lumbar muscle strain of cold dampness were randomly divided into an observation group (40 cases, 1 case dropped out) and a control group (40… Continue reading [Thermo- #electroacupuncture at #yaosanzhen for chronic #lumbar #muscle strain of cold dampness: a randomized controlled trial]
The effect of commonly used non- #antibiotic medications on #antimicrobial resistance development in #Escherichia coli
Antimicrobial resistance (AMR) poses a global threat to public health. While antibiotic overuse is a primary driver, emerging evidence suggests that non-antibiotic medications (NAMs) may also contribute. This concern is particularly relevant in residential aged care facilities (RACFs), where both NAMs and antibiotics are frequently used. We investigated whether nine commonly used NAMs in RACFs,… Continue reading The effect of commonly used non- #antibiotic medications on #antimicrobial resistance development in #Escherichia coli
Risk of #dementia following #gabapentin prescription in chronic low back #pain patients
Introduction Gabapentin is widely used to treat chronic pain, but its association with cognitive decline and dementia remains unclear. This study examined whether gabapentin prescription is associated with dementia in adults with chronic low back pain.Methods We conducted a retrospective cohort study using the TriNetX national database of de-identified patient records from 2004 to 2024.… Continue reading Risk of #dementia following #gabapentin prescription in chronic low back #pain patients
“Being away from everything”: Exploring the importance of access to #nature for individuals living with chronic low #back #pain
Highlights• Accessing nature spaces is important in the self-management of chronic low back pain.• Accessibility is undermined by disability, environmental obstacles or hazards, or proximity.• This represents an unmet clinical need which could be explored through virtual reality therapy. AbstractChronic low back pain is a persistent and debilitating condition, and therapeutic outcomes in the long… Continue reading “Being away from everything”: Exploring the importance of access to #nature for individuals living with chronic low #back #pain
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