Impact of Iron Deficiency Anemia on Outcomes After Transcatheter Aortic Valve Implantation: Insights From the Nationwide Readmission Database From 2016 to 2021

Background: Transcatheter aortic valve implantation ( #TAVI ) has become an established intervention for severe symptomatic aortic stenosis, particularly in high-risk and elderly patients. Although #anemia is frequently encountered in this population, the specific role of iron deficiency anemia (IDA) in influencing outcomes following TAVI remains underexplored.Aims: This study aims to evaluate the impact of… Continue reading Impact of Iron Deficiency Anemia on Outcomes After Transcatheter Aortic Valve Implantation: Insights From the Nationwide Readmission Database From 2016 to 2021

Atherosclerotic Cardiovascular Risk in Patients with Chronic Hepatitis B: Tenofovir Disoproxil Fumarate Vs. Tenofovir Alafenamide: A Korean Nationwide Study

#Tenofovir alafenamide (TAF) exhibits antiviral efficacy comparable to tenofovir disoproxil fumarate (TDF). Nonetheless, concerns persist regarding TAF's impact on the lipid profile and potential atherosclerotic cardiovascular disease (ASCVD) risk. This study evaluated long-term #ASCVD risk in patients with chronic hepatitis B ( #CHB ) treated with TAF or TDF using Korean National Health Insurance Service… Continue reading Atherosclerotic Cardiovascular Risk in Patients with Chronic Hepatitis B: Tenofovir Disoproxil Fumarate Vs. Tenofovir Alafenamide: A Korean Nationwide Study

Trends of myocardial infarction in young patients

Aim: While the overall incidence and mortality of ST-elevation myocardial infarction ( #STEMI ) have declined, younger adults 18-40 years of age have experienced a different trend. We examined STEMI incidence, mortality, and mechanical circulatory support (MCS) utilization in #young patients from 2004 to 2023 using the TriNetX Research Network database.Methods: We conducted an analysis… Continue reading Trends of myocardial infarction in young patients

Microvascular dysfunction in Takotsubo syndrome: a systematic review

Background: Microvascular dysfunction (MD) is advocated as one of the main pathogenic mechanisms of #Takotsubo syndrome (TTS). Several studies investigated MD in TTS using different techniques; however, no systematic review of these data is currently available.Methods: We searched the main scientific database (Embase, Medline, Scopus, PubMed) for articles written in English language using the following… Continue reading Microvascular dysfunction in Takotsubo syndrome: a systematic review

#Rate control or #rhythm control strategies for stroke prevention in atrial #fibrillation: a systematic review and network meta-analysis

Atrial fibrillation (AF) is a major cause of stroke and thromboembolic events. We aimed to assess whether, in patients with AF, rate or rhythm control strategies reduce the risk for stroke or cardiovascular events.Methods and resultsRandomized controlled trials (RCTs) comparing rate control versus rhythm control strategies were systematically searched and included in a network meta-analysis… Continue reading #Rate control or #rhythm control strategies for stroke prevention in atrial #fibrillation: a systematic review and network meta-analysis

Over-the-Counter #Supplement Overuse: A Rare Potential Cause of #Arsenic Poisoning and #Bradycardia

A 71-year-old woman with no significant past medical history presented with progressive cognitive decline, fatigue, and weight loss over two years. Her symptoms included bradycardia, anxiety, depression, and mild dyspnea on exertion. The patient followed a strict diet fortified with smoothies and an extensive regimen of 26 dietary #supplements , consumed regularly over five years.… Continue reading Over-the-Counter #Supplement Overuse: A Rare Potential Cause of #Arsenic Poisoning and #Bradycardia

Multimodality imaging in #hypertrophic #cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a myocardial disorder characterized by unexplained myocardial hypertrophy. Although the diagnosis of HCM is traditionally based on increased left ventricular (LV) wall thickness, contemporary management requires a comprehensive multimodality imaging approach to accurately define disease phenotype, assess functional consequences, and guide risk stratification. Transthoracic echocardiography remains the first-line imaging modality, providing… Continue reading Multimodality imaging in #hypertrophic #cardiomyopathy

Three vs 12-month #DAPT after implantation of biodegradable-polymer sirolimus-eluting coronary #stent : a randomised clinical trial

Early discontinuation of dual antiplatelet therapy (DAPT) within 3 months after implantation of drug-eluting stents may reduce bleeding risk without increasing ischaemic events. This study aimed to assess whether 3-month DAPT is as safe as the conventional 12-month regimen in patients treated with Firehawk stents, which have demonstrated 99.9% reendothelialisation at 3 months by optical… Continue reading Three vs 12-month #DAPT after implantation of biodegradable-polymer sirolimus-eluting coronary #stent : a randomised clinical trial

Real-World outcomes of oral #anticoagulation in patients with atrial #fibrillation at high risk of both #bleeding anand Asia-Pacificd stroke: observational evidence from three international registries from middle East, Europe

To evaluate the clinical course of patients with AF at high risk for both bleeding and stroke, according to OAC use. Data were analysed from three registries across the Middle East, Europe, and Asia-Pacific regions. The study only included 'high risk' patients with AF and CHA₂DS₂-VASc scores ≥ 2 and HAS-BLED scores ≥ 3, who… Continue reading Real-World outcomes of oral #anticoagulation in patients with atrial #fibrillation at high risk of both #bleeding anand Asia-Pacificd stroke: observational evidence from three international registries from middle East, Europe