Background: Microvascular dysfunction (MD) is advocated as one of the main pathogenic mechanisms of #Takotsubo syndrome (TTS). Several studies investigated MD in TTS using different techniques; however, no systematic review of these data is currently available.Methods: We searched the main scientific database (Embase, Medline, Scopus, PubMed) for articles written in English language using the following… Continue reading Microvascular dysfunction in Takotsubo syndrome: a systematic review
Category: Cardiology
#Rate control or #rhythm control strategies for stroke prevention in atrial #fibrillation: a systematic review and network meta-analysis
Atrial fibrillation (AF) is a major cause of stroke and thromboembolic events. We aimed to assess whether, in patients with AF, rate or rhythm control strategies reduce the risk for stroke or cardiovascular events.Methods and resultsRandomized controlled trials (RCTs) comparing rate control versus rhythm control strategies were systematically searched and included in a network meta-analysis… Continue reading #Rate control or #rhythm control strategies for stroke prevention in atrial #fibrillation: a systematic review and network meta-analysis
Over-the-Counter #Supplement Overuse: A Rare Potential Cause of #Arsenic Poisoning and #Bradycardia
A 71-year-old woman with no significant past medical history presented with progressive cognitive decline, fatigue, and weight loss over two years. Her symptoms included bradycardia, anxiety, depression, and mild dyspnea on exertion. The patient followed a strict diet fortified with smoothies and an extensive regimen of 26 dietary #supplements , consumed regularly over five years.… Continue reading Over-the-Counter #Supplement Overuse: A Rare Potential Cause of #Arsenic Poisoning and #Bradycardia
Multimodality imaging in #hypertrophic #cardiomyopathy
Hypertrophic cardiomyopathy (HCM) is a myocardial disorder characterized by unexplained myocardial hypertrophy. Although the diagnosis of HCM is traditionally based on increased left ventricular (LV) wall thickness, contemporary management requires a comprehensive multimodality imaging approach to accurately define disease phenotype, assess functional consequences, and guide risk stratification. Transthoracic echocardiography remains the first-line imaging modality, providing… Continue reading Multimodality imaging in #hypertrophic #cardiomyopathy
Three vs 12-month #DAPT after implantation of biodegradable-polymer sirolimus-eluting coronary #stent : a randomised clinical trial
Early discontinuation of dual antiplatelet therapy (DAPT) within 3 months after implantation of drug-eluting stents may reduce bleeding risk without increasing ischaemic events. This study aimed to assess whether 3-month DAPT is as safe as the conventional 12-month regimen in patients treated with Firehawk stents, which have demonstrated 99.9% reendothelialisation at 3 months by optical… Continue reading Three vs 12-month #DAPT after implantation of biodegradable-polymer sirolimus-eluting coronary #stent : a randomised clinical trial
Real-World outcomes of oral #anticoagulation in patients with atrial #fibrillation at high risk of both #bleeding anand Asia-Pacificd stroke: observational evidence from three international registries from middle East, Europe
To evaluate the clinical course of patients with AF at high risk for both bleeding and stroke, according to OAC use. Data were analysed from three registries across the Middle East, Europe, and Asia-Pacific regions. The study only included 'high risk' patients with AF and CHA₂DS₂-VASc scores ≥ 2 and HAS-BLED scores ≥ 3, who… Continue reading Real-World outcomes of oral #anticoagulation in patients with atrial #fibrillation at high risk of both #bleeding anand Asia-Pacificd stroke: observational evidence from three international registries from middle East, Europe
An Analysis of Initial Loop #Diuretic Dosing Strategies and Its Association with Time to #Decongestion
Background: There is currently a lack of evidence on the optimal loop diuretic dosing strategy in cases of acute decompensated heart failure (ADHF). Current consensus recommendations suggest starting with a dose of at least 2 times the patient’s home loop diuretic dose. Objective: This study assessed whether higher initial loop diuretic doses are associated with… Continue reading An Analysis of Initial Loop #Diuretic Dosing Strategies and Its Association with Time to #Decongestion
The Overlooked Driver of #Hypertension: Mental #Stress at the Crossroad of Cardiology and Psychiatry
AbstractPurpose of ReviewMental stress has long been overlooked in the development of hypertension. We aim to provide new insights for clinicians in managing this condition.This review aims to summarize the epidemiological characteristics, complex mechanisms, diagnostic methods, as well as both non-pharmacological and pharmacological treatment strategies for mental stress-induced hypertension.Recent FindingsMany hypertensive patients continue to experience… Continue reading The Overlooked Driver of #Hypertension: Mental #Stress at the Crossroad of Cardiology and Psychiatry
Inhibition of CXCL10 and IFN-γ ameliorates #myocarditis in preclinical models of SARS-CoV-2 #mRNA vaccination
Messenger RNA (mRNA) vaccines against SARS-CoV-2 are highly effective and were instrumental in curbing the COVID-19 pandemic. However, rare cases of noninfective myocarditis, particularly in young males and typically after the second dose, have been observed. Here, we explore the mediators of this myocarditis to better understand and to enhance the safety of future mRNA… Continue reading Inhibition of CXCL10 and IFN-γ ameliorates #myocarditis in preclinical models of SARS-CoV-2 #mRNA vaccination
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