Psychotherapy for Depression Across Different Age Groups: A Systematic Review and Meta-analysis

..After removing duplicates, 16 756 records were screened and 2608 full-text articles were screened. Of these, 366 trials (36 702 patients) with 453 comparisons between a therapy and a control condition were included in the qualitative analysis, including 13 (3.6%) in children (13 years and younger), 24 (6.6%) in adolescents (≥13 to 18 years), 19 (5.2%) in… Continue reading Psychotherapy for Depression Across Different Age Groups: A Systematic Review and Meta-analysis

#Acne vulgaris and risk of #depression and #anxiety: A meta-analytic review

Several studies have shown an association of acne vulgaris with depression and anxiety, but a quantitative review has not yet been conducted.. Forty-two studies were included. We found a significant association of acne vulgaris with depression ( r = 0.22 [95% confidence interval 0.17-0.26, P < .00001]) and anxiety ( r = 0.25 [95% confidence… Continue reading #Acne vulgaris and risk of #depression and #anxiety: A meta-analytic review

Outcomes of Online #Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms A Randomized Clinical Trial

Patients with residual depressive symptoms face a gap in care because few resources, to date, are available to manage the lingering effects of their illness.. To evaluate the effectiveness for treating residual depressive symptoms with Mindful Mood Balance (MMB), a web-based application that delivers mindfulness-based cognitive therapy, plus usual depression care compared with usual depression… Continue reading Outcomes of Online #Mindfulness-Based Cognitive Therapy for Patients With Residual Depressive Symptoms A Randomized Clinical Trial

Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models

..Stable treatment response, intended as a proxy for treatment effectiveness, defined as continued prescription of an antidepressant for 90 days. Supervised topic models were used to extract 10 interpretable covariates from coded clinical data for stability prediction. With use of data from 1 hospital system (site A), generalized linear models and ensembles of decision trees… Continue reading Assessment of a Prediction Model for Antidepressant Treatment Stability Using Supervised Topic Models

Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis

..Eligibility criteria for selecting studies We included randomised controlled trials with a yoga intervention comprising ≥50% physical activity in adults with a recognised diagnosed mental disorder according to DSM-3, 4 or 5. Results 19 studies were included in the review (1080 participants) and 13 studies were included in the meta-analysis (632 participants). Disorders of depression,… Continue reading Effects of #yoga on depressive symptoms in people with mental disorders: a systematic review and meta-analysis

#Circadian rhythm and sleep alterations in older people with lifetime #depression: a case-control study

Depression is common in older people and is associated with underlying brain change increasing the risk of dementia. Sleep disturbance is frequently reported by those with lifetime depression, however whether circadian misalignment also exists is unclear. We aimed to examine circadian rhythms and sleep associations in older patients with and without lifetime depression.. ..Participants underwent… Continue reading #Circadian rhythm and sleep alterations in older people with lifetime #depression: a case-control study

Inflammatory modulation of #fluoxetine use in patients with #depression: A systematic review and meta-analysis

There is growing evidence that there is a relationship between major depressive disorder (MDD), also simply known as “depression”, and inflammatory processes. Selective serotonin inhibitors, such as fluoxetine, are used as a first-line treatment for depression, and it is hypothesized that its use can reduce levels of proinflammatory cytokines. The aim of this systematic review… Continue reading Inflammatory modulation of #fluoxetine use in patients with #depression: A systematic review and meta-analysis

#Mood Homeostasis, Low Mood, and History of #Depression in 2 Large Population Samples

..To assess whether mood homeostasis (ie, the stabilization of one’s mood by engaging in mood-modifying activities) is a possible new therapeutic target by testing the hypothesis that people with low (vs high) mean mood and people with (vs without) a history of depression have impaired mood homeostasis.. ..A total of 28 212 participants from the 58sec… Continue reading #Mood Homeostasis, Low Mood, and History of #Depression in 2 Large Population Samples

Association Between Lifetime Affective Symptoms and Premature Mortality

Associations between affective problems (anxiety and depression) and premature mortality have been demonstrated among psychiatric, medical, and community-based samples and across many causes of death.. ..Of 3001 study members (1509 [50.3%] female, 1492 [49.7%] male), 235 individuals (7.8%) died over a 15-year follow-up. After adjustment for sex, those who experienced case-level affective symptoms 1, 2,… Continue reading Association Between Lifetime Affective Symptoms and Premature Mortality