Understanding the biological basis of social anxiety disorder (SAD), one of the most disabling of the anxiety disorders, will allow for novel treatment strategies to be developed. Here, we show that gut microbiota may be such a target. Mice that received SAD patient microbiota had a specific heightened sensitivity to social fear without affecting other… Continue reading Social #anxiety disorder-associated gut #microbiota increases #social #fear
Tag: anxiety
The Impact of Gut #Microbiota on the Development of #Anxiety Symptoms—A Narrative Review
The gut microbiota plays a key role in mental health, with growing evidence linking its composition to anxiety and depressive disorders. Research on this topic has expanded significantly in recent years. This review explores alterations in the gut microbiota of individuals with anxiety disorders and examines the potential therapeutic effects of probiotics. Background/Objectives: This review… Continue reading The Impact of Gut #Microbiota on the Development of #Anxiety Symptoms—A Narrative Review
Microbial metabolites tune #amygdala neuronal hyperexcitability and #anxiety-linked behaviors
Changes in gut microbiota composition have been linked to anxiety behavior in rodents. However, the underlying neural circuitry linking microbiota and their metabolites to anxiety behavior remains unknown. Using male C57BL/6J germ-free (GF) mice, not exposed to live microbes, increased anxiety-related behavior was observed correlating with a significant increase in the immediate early c-Fos gene… Continue reading Microbial metabolites tune #amygdala neuronal hyperexcitability and #anxiety-linked behaviors
#Mindfulness Meditation vs #Escitalopram for Treatment of #Anxiety DisordersSecondary Analysis of a Randomized Clinical Trial
IntroductionMindfulness-based interventions, such as mindfulness-based stress reduction (MBSR), have shown efficacy for anxiety disorders.1 We previously demonstrated that 8 weeks of MBSR was noninferior to escitalopram for treatment of anxiety disorders in a fully powered, multisite, noninferiority parallel-group randomized clinical trial with a predetermined margin.2 We present secondary outcomes of the trial, including patient-reported anxiety,… Continue reading #Mindfulness Meditation vs #Escitalopram for Treatment of #Anxiety DisordersSecondary Analysis of a Randomized Clinical Trial
The effect of #anxiety on all-cause #dementia: A longitudinal analysis from the Hunter Community Study
BackgroundAnxiety is common, however, the effect of chronicity of anxiety on dementia has not been explored. This study aims to assess the longitudinal relationship between chronic versus resolved versus new onset anxiety, and all-cause dementia risk.MethodsA total of 2132 participants with mean age 76 years from the Hunter Community Study were recruited. Anxiety was measured using… Continue reading The effect of #anxiety on all-cause #dementia: A longitudinal analysis from the Hunter Community Study
#High-fat diet, #microbiome-gut-brain axis signaling, and #anxiety-like behavior in male rats
Obesity, associated with the intake of a high-fat diet (HFD), and anxiety are common among those living in modern urban societies. Recent studies suggest a role of microbiome-gut-brain axis signaling, including a role for brain serotonergic systems in the relationship between HFD and anxiety. Evidence suggests the gut microbiome and the serotonergic brain system together… Continue reading #High-fat diet, #microbiome-gut-brain axis signaling, and #anxiety-like behavior in male rats
Personalized brain circuit scores identify clinically distinct biotypes in #depression and #anxiety
There is an urgent need to derive quantitative measures based on coherent neurobiological dysfunctions or ‘biotypes’ to enable stratification of patients with depression and anxiety. We used task-free and task-evoked data from a standardized functional magnetic resonance imaging protocol conducted across multiple studies in patients with depression and anxiety when treatment free (n = 801) and after… Continue reading Personalized brain circuit scores identify clinically distinct biotypes in #depression and #anxiety
Long-term exposure to residential #greenness and decreased risk of #depression and #anxiety
Residential greenness is considered a unique and potentially modifiable exposure construct to reduce physiological stress and improve human health. Here this study aims to investigate the longitudinal relationships of residential greenness with incident depression and anxiety and to explore and compare the pathways in which greenery may influence mental health. After excluding participants with depression… Continue reading Long-term exposure to residential #greenness and decreased risk of #depression and #anxiety
Most #GLP-1 Medications Correlated with a Lower Likelihood of #Anxiety and #Depression Diagnoses
Key FindingsDiabetic patients prescribed tirzepatide, semaglutide, dulaglutide, and exenatide are less likely to be diagnosed with depression after starting the medication compared to those not on a glucagon-like peptide-1 receptor agonist (GLP-1) medication. The likelihood of anxiety in diabetic patients is lower for those on all five GLP-1 medications studied. Among non-diabetic patients, semaglutide is correlated with… Continue reading Most #GLP-1 Medications Correlated with a Lower Likelihood of #Anxiety and #Depression Diagnoses
2 Medical News 