Tag: syndrome

Exploring White Matter Microstructural Abnormalities Using MRI in Women With Premenstrual Dysphoric Disorder via Brain Connectome

aledopress

Background: The neurostructural underpinnings of #premenstrual dysphoric disorder (PMDD), particularly integrated white matter and network alteration, remain unclear.Purpose: To identify a core structural network in PMDD by integrating multiple diffusion tensor imaging (DTI)-derived metrics and to develop a predictive model.Study type: Prospective case-control study.Subjects: Forty-two PMDD patients (age: 23.86 ± 1.32 years), diagnosed according to… Continue reading Exploring White Matter Microstructural Abnormalities Using MRI in Women With Premenstrual Dysphoric Disorder via Brain Connectome

Development and validation of blood-based diagnostic biomarkers for #Myalgic #Encephalomyelitis/#Chronic Fatigue Syndrome (ME/CFS) using EpiSwitch® 3-dimensional genomic regulatory immuno-genetic profiling

aledopress

Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a debilitating, multifactorial disorder characterised by profound fatigue, post-exertional malaise, cognitive impairments, and autonomic dysfunction. Despite its significant impact on quality of life, ME/CFS lacks definitive diagnostic biomarkers, complicating diagnosis and management. Recent evidence highlights potential blood tests for ME/CFS biomarkers in immunological, genetic, metabolic, and bioenergetic domains. Chromosome… Continue reading Development and validation of blood-based diagnostic biomarkers for #Myalgic #Encephalomyelitis/#Chronic Fatigue Syndrome (ME/CFS) using EpiSwitch® 3-dimensional genomic regulatory immuno-genetic profiling