Pro-inflammatory dietary patterns are associated with increased pain and functional disability in sciatica: a hospital-based cross-sectional study

Background: #Sciatica is a common neuropathic pain condition associated with substantial functional disability. Emerging evidence suggests that #diet -induced inflammation may play a role in chronic pain development. However, the association between dietary inflammatory potential and clinical outcomes in sciatica remains unclear.Methods: In this cross-sectional study, we enrolled 598 patients diagnosed with sciatica from two… Continue reading Pro-inflammatory dietary patterns are associated with increased pain and functional disability in sciatica: a hospital-based cross-sectional study

Effects of Acupuncture on Time-Dependent Muscle Endurance in Men with Post-Anterior Cruciate Ligament Injury: A Randomized Controlled Crossover Trial

To investigate whether acupuncture enhances knee joint muscle endurance effectiveness and time-dependent effects after anterior cruciate ligament ( #ACL ) injuries.Methods:This randomized, single-blinded crossover trial included 20 males with ACL injuries. Participants were randomly divided into real acupuncture (RA) group and sham acupuncture (SA) group. RA was stimulated at ST32, ST34, ST36, SP10, and BL57;… Continue reading Effects of Acupuncture on Time-Dependent Muscle Endurance in Men with Post-Anterior Cruciate Ligament Injury: A Randomized Controlled Crossover Trial

Effectiveness of Non-Pharmacological Interventions for Hormone Therapy-Induced #Hand #Arthralgia in Breast Cancer Patients: A Systematic Review

BackgroundAromatase inhibitor-induced arthralgia (AIA) is a frequent adverse effect of endocrine therapy in breast cancer survivors, often leading to treatment modification or discontinuation. Non-pharmacological interventions have been proposed to manage AIA, but evidence remains fragmented.ObjectiveTo synthesize recent randomized controlled trials (RCTs) evaluating the efficacy of non-pharmacological interventions for AIA.MethodsA systematic search of PubMed, Scopus, and… Continue reading Effectiveness of Non-Pharmacological Interventions for Hormone Therapy-Induced #Hand #Arthralgia in Breast Cancer Patients: A Systematic Review

Pain management in the perioperative orthogeriatric setting: Recommendations of the special interest group Orthogeriatrics of the German Geriatrics Society

Management of perioperative pain in older adults can be challenging. Multimorbidity, functional decline or diminished physiological reserves, the corresponding polypharmacy, age-related pharmacodynamic and pharmacokinetic changes need to be considered. #Pain assessment can be complicated by cognitive impairment and communication barriers. Older adults are at high risk of adverse consequences from surgery and undertreated pain as… Continue reading Pain management in the perioperative orthogeriatric setting: Recommendations of the special interest group Orthogeriatrics of the German Geriatrics Society

Cefazolin and the R1 Side Chain: Why Patients with a Cephalosporin Allergy Can Be Safely Given Cefazolin While Undergoing Joint Arthroplasty

Background: #Cefazolin , a first-generation #cephalosporin , is the standard antibiotic for perioperative prophylaxis in patients undergoing hip or knee arthroplasty. Research has demonstrated significantly higher periprosthetic joint infection ( #PJI ) rates when non-cefazolin antibiotics are used for prophylaxis. Notably, cefazolin contains an R1 side chain that has not shown cross-reactivity with other cephalosporins.… Continue reading Cefazolin and the R1 Side Chain: Why Patients with a Cephalosporin Allergy Can Be Safely Given Cefazolin While Undergoing Joint Arthroplasty

Synovial interleukin-6 point-of-care testing, alone and combined with D-dimer, supports rapid diagnosis of periprosthetic joint infection

Purpose: Data on the reliability of point-of-care (POC) tests for the rapid diagnosis of periprosthetic joint infections (PJI) using synovial fluid (SF) #D-dimer (DD), interleukin 6 (IL-6) and procalcitonin (PCT) are limited. This study aimed to address this issue by evaluating the diagnostic accuracy of POC tests for SF DD, IL-6 and PCT in comparison… Continue reading Synovial interleukin-6 point-of-care testing, alone and combined with D-dimer, supports rapid diagnosis of periprosthetic joint infection

Revisiting D-dimer in periprosthetic joint infection: a comprehensive systematic review and meta-analysis with subgroup and heterogeneity exploration

Background: #D-dimer has gained considerable attention since its inclusion as a minor criterion in the 2018 International Consensus Meeting. However, evidence regarding its diagnostic accuracy for periprosthetic joint infection ( #PJI ) remains inconclusive. This systematic review and meta-analysis aimed to evaluate the diagnostic performance of D-dimer in diagnosing PJI and comprehensively explore the sources… Continue reading Revisiting D-dimer in periprosthetic joint infection: a comprehensive systematic review and meta-analysis with subgroup and heterogeneity exploration

#Knee flexion during skin preparation improves anterior #antiseptic coverage: A controlled fluorescent dye study

AbstractBackground: Periprosthetic joint infection ( #PJI ) is a rare but devastating complication of total knee arthroplasty (TKA) and a leading cause of TKA failure. Thorough skin preparation is a key preventative measure; however, the influence of limb position on antiseptic coverage has not been evaluated. This study compared the effectiveness of anterior knee antiseptic… Continue reading #Knee flexion during skin preparation improves anterior #antiseptic coverage: A controlled fluorescent dye study

Cost-Effectiveness of #Acupuncture Needling for Older Adults With Chronic Low #Back Pain

Preplanned economic evaluation alongside a clinical trial.Objective. Determine the 1-year cost-effectiveness from health care sector and Medicare perspectives of adding either standard #acupuncture (SA; ≤15 treatment sessions over 12 wk) or enhanced acupuncture (EA; SA plus ≤ 6 additional sessions) to usual medical care (UMC) versus UMC alone.Summary of Background Data. Chronic low back #pain… Continue reading Cost-Effectiveness of #Acupuncture Needling for Older Adults With Chronic Low #Back Pain