Background: #Cefazolin , a first-generation #cephalosporin , is the standard antibiotic for perioperative prophylaxis in patients undergoing hip or knee arthroplasty. Research has demonstrated significantly higher periprosthetic joint infection ( #PJI ) rates when non-cefazolin antibiotics are used for prophylaxis. Notably, cefazolin contains an R1 side chain that has not shown cross-reactivity with other cephalosporins.… Continue reading Cefazolin and the R1 Side Chain: Why Patients with a Cephalosporin Allergy Can Be Safely Given Cefazolin While Undergoing Joint Arthroplasty
Category: Orthopedy
Synovial interleukin-6 point-of-care testing, alone and combined with D-dimer, supports rapid diagnosis of periprosthetic joint infection
Purpose: Data on the reliability of point-of-care (POC) tests for the rapid diagnosis of periprosthetic joint infections (PJI) using synovial fluid (SF) #D-dimer (DD), interleukin 6 (IL-6) and procalcitonin (PCT) are limited. This study aimed to address this issue by evaluating the diagnostic accuracy of POC tests for SF DD, IL-6 and PCT in comparison… Continue reading Synovial interleukin-6 point-of-care testing, alone and combined with D-dimer, supports rapid diagnosis of periprosthetic joint infection
Revisiting D-dimer in periprosthetic joint infection: a comprehensive systematic review and meta-analysis with subgroup and heterogeneity exploration
Background: #D-dimer has gained considerable attention since its inclusion as a minor criterion in the 2018 International Consensus Meeting. However, evidence regarding its diagnostic accuracy for periprosthetic joint infection ( #PJI ) remains inconclusive. This systematic review and meta-analysis aimed to evaluate the diagnostic performance of D-dimer in diagnosing PJI and comprehensively explore the sources… Continue reading Revisiting D-dimer in periprosthetic joint infection: a comprehensive systematic review and meta-analysis with subgroup and heterogeneity exploration
#Knee flexion during skin preparation improves anterior #antiseptic coverage: A controlled fluorescent dye study
AbstractBackground: Periprosthetic joint infection ( #PJI ) is a rare but devastating complication of total knee arthroplasty (TKA) and a leading cause of TKA failure. Thorough skin preparation is a key preventative measure; however, the influence of limb position on antiseptic coverage has not been evaluated. This study compared the effectiveness of anterior knee antiseptic… Continue reading #Knee flexion during skin preparation improves anterior #antiseptic coverage: A controlled fluorescent dye study
Cost-Effectiveness of #Acupuncture Needling for Older Adults With Chronic Low #Back Pain
Preplanned economic evaluation alongside a clinical trial.Objective. Determine the 1-year cost-effectiveness from health care sector and Medicare perspectives of adding either standard #acupuncture (SA; ≤15 treatment sessions over 12 wk) or enhanced acupuncture (EA; SA plus ≤ 6 additional sessions) to usual medical care (UMC) versus UMC alone.Summary of Background Data. Chronic low back #pain… Continue reading Cost-Effectiveness of #Acupuncture Needling for Older Adults With Chronic Low #Back Pain
The effect of post-operative continuous negative pressure therapy after debridement, antibiotics, and implant retention for acute #periprosthetic joint infection
Background: Acute periprosthetic joint infection (#PJI ) is a serious complication after total knee and hip replacement, with varying success rates in its management using debridement, antibiotics, and implant retention (DAIR). We hypothesize that the application of post-operative continuous negative pressure therapy (CNPT) can improve the success rate of DAIR in the treatment of acute… Continue reading The effect of post-operative continuous negative pressure therapy after debridement, antibiotics, and implant retention for acute #periprosthetic joint infection
Effect of core stabilization exercises on #lumbar multifidus morphology and functional outcomes in chronic non-specific low #back pain: a randomized controlled trial
Background: Chronic non-specific low back pain (CNSLBP) is often associated with morphological changes in the lumbar multifidus muscle (LMF), such as reduced cross-sectional area (CSA) and increased fat infiltration, compromising spinal stability and function. Core stabilization exercises aim to enhance neuromuscular control by targeting deep trunk muscles. However, few randomized trials have investigated their effects… Continue reading Effect of core stabilization exercises on #lumbar multifidus morphology and functional outcomes in chronic non-specific low #back pain: a randomized controlled trial
Effect of #acupuncture intervention combined with lateral approach #sciatic nerve block on postoperative analgesia in patients after total #knee #arthroplasty
Objectives: To explore the effect of acupuncture intervention combined with lateral approach sciatic nerve block (LSNB) on postoperative analgesia in patients after total knee arthroplasty (TKA).Methods: A total of 90 patients scheduled for TKA between May 2022 and May 2024 were selected as the study subjects. They were randomly divided into a control group and… Continue reading Effect of #acupuncture intervention combined with lateral approach #sciatic nerve block on postoperative analgesia in patients after total #knee #arthroplasty
Clinical outcomes of #orthopaedic surgery patients with inferior vena #cava filter prophylaxis
AbstractPurpose: Orthopaedic surgery patients are at an elevated risk of venous thromboembolic events thus necessitating effective prophylaxis strategies.Methods: This IRB-approved, single-center retrospective study evaluated patients who underwent orthopaedic surgery and were protected with Inferior Vena Cava (IVC) filters from January 2007 to December 2021. Study outcomes include incidence of venous thromboembolism (VTE) in the form… Continue reading Clinical outcomes of #orthopaedic surgery patients with inferior vena #cava filter prophylaxis
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