#Emotion regulation strategies differentially impact memory in #hormonal #contraceptive users

Highlights•HC users show greater emotional reactivity compared to NC females.•Distancing reduces negative affect in HC users compared to NC females.•HC users exhibit memory modulation for emotional images by emotion regulation. AbstractHormonal contraceptives (HCs) are widely used, yet their effects on emotional and cognitive processes remain poorly understood. This study examined how HC use may influence… Continue reading #Emotion regulation strategies differentially impact memory in #hormonal #contraceptive users

Early prenatal #nitrate exposure and #birth outcomes: A study of Iowa’s public drinking water (1970–1988)

Despite the biological mechanisms linking prenatal nitrate exposure to birth outcomes, epidemiological research has been inconclusive. The evidence-base has been limited by where and how nitrate exposure was measured, and the spurious correlation between geotemporal nitrate heterogeneity and unmeasurable factors contributing to gestational age and birth weight. We linked Iowa water quality data and birth… Continue reading Early prenatal #nitrate exposure and #birth outcomes: A study of Iowa’s public drinking water (1970–1988)

Short-Term Cardiometabolic Response to #Mango Intake in Post #menopausal #Women

Consumption of mangos has been associated with improved diet quality, with reported reductions in systolic blood pressure and inflammatory biomarkers when consumed daily in robust amounts for six to eight weeks. Whether these changes could occur with a shorter intake period is unknown.MethodsThis study explored the effect of two weeks of mango intake (330 g/d) on… Continue reading Short-Term Cardiometabolic Response to #Mango Intake in Post #menopausal #Women

Impact of #mRNA and Inactivated COVID-19 Vaccines on #Ovarian Reserve

Objectives: This study aimed to elucidate the effects of messenger RNA (mRNA) and inactivated coronavirus disease 2019 (COVID-19) vaccines on ovarian histology and reserve in rats. Methods: Thirty female Wistar albino rats, aged 16–24 weeks, were randomly divided into three groups (n = 10): control, mRNA vaccine, and inactivated vaccine groups. Each vaccine group received… Continue reading Impact of #mRNA and Inactivated COVID-19 Vaccines on #Ovarian Reserve

Mammographic classification of interval breast cancers and #artificial intelligence performance

European studies suggest artificial intelligence (AI) can reduce interval breast cancers (IBCs). However, research on IBC classification and AI’s effectiveness in the U.S., particularly using digital breast tomosynthesis (DBT) and annual screening, is limited. We aimed to mammographically classify IBCs and assess AI performance using a 12-month screening interval.MethodsFrom digital mammography (DM) and DBT screening… Continue reading Mammographic classification of interval breast cancers and #artificial intelligence performance

#Endometriosis and uterine #fibroids and risk of premature mortality: prospective cohort study

Objective To prospectively assess the effect of endometriosis and uterine fibroids on the long term risk of premature mortality (younger than 70 years).Design Prospective cohort studySetting The Nurses’ Health Study II, United States (1989-2019).Participants 110 091 women aged 25-42 years in 1989 without a history of hysterectomy before endometriosis or fibroids diagnosis, cardiovascular diseases, or cancer.Main… Continue reading #Endometriosis and uterine #fibroids and risk of premature mortality: prospective cohort study

High #sperm deoxyribonucleic acid fragmentation index is associated with an increased risk of #preeclampsia following assisted reproduction treatment

ObjectiveTo study the association between sperm deoxyribonucleic acid fragmentation index (DFI) and the odds of preeclampsia and other adverse perinatal outcomes after in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI) treatment. DesignA prospective cohort study including infertile couples undergoing conventional IVF or ICSI treatment and their children. Data regarding preeclampsia and perinatal outcomes were… Continue reading High #sperm deoxyribonucleic acid fragmentation index is associated with an increased risk of #preeclampsia following assisted reproduction treatment

Identification of distinct #stool metabolites in women with #endometriosis for non-invasive diagnosis and potential for microbiota-based therapies

Context and significanceClinical management of endometriosis, a gynecological disease that is a leading cause of infertility in women, remains a challenge with no known cure. Scientists from Baylor College of Medicine combined the gut metabolomic and microbiota signatures in the stool samples from women with endometriosis to identify a gut-bacteria-derived therapeutic intervention candidate, 4-hydroxyindole. They… Continue reading Identification of distinct #stool metabolites in women with #endometriosis for non-invasive diagnosis and potential for microbiota-based therapies

Premenopausal bilateral #oophorectomy and #brain white matter brain integrity in later-life

INTRODUCTIONPremenopausal bilateral oophorectomy (PBO) is associated with later-life cognition, but the underlying brain changes remain unclear. We assessed the impact of PBO and PBO age on white matter integrity.METHODSFemale participants with regional diffusion tensor imaging (DTI) metrics of fractional anisotropy (FA) and mean diffusivity (MD) were included (22 with PBO < 40 years; 43 with PBO 40-45… Continue reading Premenopausal bilateral #oophorectomy and #brain white matter brain integrity in later-life