Postprandial distress syndrome (PDS) is the most common subtype of functional dyspepsia. Acupuncture is commonly used to treat PDS, but its effect is uncertain because of the poor quality of prior studies.. ..Results: Among the 278 randomly assigned participants, 228 (82%) completed outcome measurements at week 16. The estimated response rate from generalized linear mixed… Continue reading Effect of Acupuncture for Postprandial Distress Syndrome
Category: Gastroenterology
High incidence of #hepatocellular carcinoma and #cirrhotic complications in patients with psychiatric illness: a territory-wide cohort study
Because of high-risk behaviours, sedentary lifestyle and side effects of medications, psychiatric patients are at risk of viral hepatitis, alcohol-related liver disease and non-alcoholic fatty liver disease. We aimed to study the incidence of hepatocellular carcinoma (HCC) and cirrhotic complications in psychiatric patients.. ..We included 105,763 psychiatric patients without prior liver-related events in the final… Continue reading High incidence of #hepatocellular carcinoma and #cirrhotic complications in patients with psychiatric illness: a territory-wide cohort study
Prediction of liver fibrosis severity in alcoholic liver disease by human microfibrillar‐associated protein 4
Background Alcoholic liver disease (ALD) is a public health concern that is the cause of half of all cirrhosis‐related deaths. Early detection of fibrosis, ideally in the pre‐cirrhotic stage, is a key strategy for improving ALD outcomes and for preventing progression to cirrhosis. Previous studies identified the blood‐borne marker human microfibrillar‐associated protein 4 (MFAP4) as… Continue reading Prediction of liver fibrosis severity in alcoholic liver disease by human microfibrillar‐associated protein 4
Dietary Patterns Are Associated with Likelihood of Hepatic #Steatosis among US Adults
Non‐alcoholic fatty liver disease (NAFLD) is a rapidly growing public health problem. In this study, we explored the association between dietary patterns (DPs) and fatty liver and liver function tests.. ..Of the 20643 eligible participants, 45.7% had prevalent fatty liver. Three DPs collectively explained 50.8% of variance in dietary nutrients consumption. The first DP was… Continue reading Dietary Patterns Are Associated with Likelihood of Hepatic #Steatosis among US Adults
CDC Hepatitis C screening among adults
..CDC is augmenting previous guidance with two new recommendations: 1) hepatitis C screening at least once in a lifetime for all adults aged ≥18 years, except in settings where the prevalence of HCV infection is <0.1% and 2) hepatitis C screening for all pregnant women during each pregnancy, except in settings where the prevalence of… Continue reading CDC Hepatitis C screening among adults
Heat-inactivated #Bifidobacterium bifidum MIMBb75 (SYN-HI-001) in the treatment of #irritable bowel syndrome: a multicentre, randomised, double-blind, placebo-controlled clinical trial
Bifidobacterium bifidum MIMBb75 is one of a few probiotic strains that have been shown to be effective in the treatment of irritable bowel syndrome (IBS) and its symptoms. Non-viable strains might have advantages over viable bacteria for product stability and standardisation, as well as for tolerability because safety concerns have been raised for specific patient… Continue reading Heat-inactivated #Bifidobacterium bifidum MIMBb75 (SYN-HI-001) in the treatment of #irritable bowel syndrome: a multicentre, randomised, double-blind, placebo-controlled clinical trial
Association Between #Celiac Disease and Mortality Risk in a Swedish Population
There were 49 829 patients with celiac disease, including 24% who were diagnosed between the years 2010 and 2017. The mean (SD) age at diagnosis was 32.2 (25.2) years and 62.4% were women. During a median follow-up time of 12.5 years, 13.2% (n = 6596) died. Compared with controls (n = 246 426), overall mortality was increased in those with celiac… Continue reading Association Between #Celiac Disease and Mortality Risk in a Swedish Population
Central sensory-motor crosstalk in the neural gut-brain axis
The neural gut-brain axis consists of viscerosensory and autonomic motor neurons innervating the gastrointestinal (GI) tract. Sensory neurons transmit nutrient-related and non-nutrient-related information to the brain, while motor neurons regulate GI motility and secretion. Previous research provides an incomplete picture of the brain nuclei that are directly connected with the neural gut-brain axis, and no… Continue reading Central sensory-motor crosstalk in the neural gut-brain axis
Timing of #Endoscopy for Acute Upper Gastrointestinal #Bleeding
To evaluate whether urgent endoscopy improves outcomes in patients predicted to be at high risk for further bleeding or death, we randomly assigned patients with overt signs of acute upper gastrointestinal bleeding and a Glasgow–Blatchford score of 12 or higher (scores range from 0 to 23, with higher scores indicating a higher risk of further… Continue reading Timing of #Endoscopy for Acute Upper Gastrointestinal #Bleeding
2 Medical News 