The clinical benefit of fresh frozen plasma ( #FFP ) transfusion prior to endoscopy in patients with acute upper gastrointestinal bleeding (AUGIB) and mild coagulopathy remains uncertain. We evaluated the association between pre-endoscopic FFP transfusion and clinical outcomes in patients with AUGIB and an international normalized ratio (INR) of 1.5-2.5. We conducted a retrospective two-center… Continue reading Association of pre-endoscopic fresh frozen plasma transfusion with clinical outcomes in patients with acute upper gastrointestinal bleeding and mild coagulopathy: a two-center retrospective cohort study
Category: Gastroenterology
#Hepatitis E Infection in Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis
Opportunistic infections are increasingly recognised in patients with inflammatory bowel disease ( #IBD ), particularly among those receiving immunosuppressive therapy. Hepatitis E virus ( #HEV ) is a leading cause of acute viral hepatitis worldwide, yet its relevance in IBD remains insufficiently clarified. This systematic review and meta-analysis aimed to explore the association between HEV… Continue reading #Hepatitis E Infection in Patients With Inflammatory Bowel Diseases: A Systematic Review and Meta-Analysis
Electroacupuncture at Baliao Points Alleviates Ulcerative Colitis via α7nAChR-Mediated Macrophage Polarization and Gut Microbiota Modulation
Ulcerative colitis ( #UC ) is a chronic inflammatory disorder characterized by a significant unmet clinical need for more effective and tolerable therapies. This study explores the therapeutic potential and underlying mechanisms of electroacupuncture (EA) at the Baliao acupoints in a dextran sulfate sodium (DSS)-induced UC rat model. EA treatment significantly alleviated colitis symptoms, restored… Continue reading Electroacupuncture at Baliao Points Alleviates Ulcerative Colitis via α7nAChR-Mediated Macrophage Polarization and Gut Microbiota Modulation
How to predict abnormal acid reflux: recent developments
IntroductionRecent advances in physiology and technology have led to the identification of additional parameters that have the potential to enhance diagnostic accuracy and inform the management of Gastroesophageal reflux disease ( #GERD ). Whilst traditional pH monitoring and acid exposure time (AET) remain central to diagnosis, recent advances have introduced novel physiological markers that improve… Continue reading How to predict abnormal acid reflux: recent developments
Increased Prevalence of Pulmonary Diseases in Patients With Inflammatory Bowel Disease
Inflammatory bowel disease ( #IBD ) is a multisystem illness with intestinal and extraintestinal manifestations. We aimed to analyze the association of developing #pulmonary diseases (PDs) in patients with IBD.Methods: In this retrospective cohort study, TriNetX was used to identify patients with IBD who were prescribed at least one IBD-specific medication or advanced therapy. Patients… Continue reading Increased Prevalence of Pulmonary Diseases in Patients With Inflammatory Bowel Disease
Laparoscopic peritoneal lavage versus surgical resection for the treatment of complicated perforated diverticulitis: A systematic review and meta-analysis
Introduction: Colonic diverticular disease ( #diverticulosis ) is a currently worldwide increasing gastrointestinal disorder with a particularly high prevalence in Western countries. The operative treatment of acute diverticulitis could be executed through open or laparoscopic techniques. A non-resectional procedure, namely laparoscopic peritoneal lavage (LPL) and drainage, has also been adopted as a less invasive treatment… Continue reading Laparoscopic peritoneal lavage versus surgical resection for the treatment of complicated perforated diverticulitis: A systematic review and meta-analysis
Effect of #statin use on prognostic outcomes in #hepatocellular carcinoma following #liver surgery: a systematic review and meta-analysis
Hepatocellular carcinoma (HCC) recurrence remains a significant clinical challenge, even among patients who undergo surgical treatment. Although statins exhibit anticancer properties through several biologically plausible mechanisms, robust clinical evidence supporting their role in preventing HCC recurrence is still limited. This meta-analysis aimed to evaluate the impact of statin use on the prognostic outcomes of patients… Continue reading Effect of #statin use on prognostic outcomes in #hepatocellular carcinoma following #liver surgery: a systematic review and meta-analysis
The health effects of #diaphragmatic #breathing: A systematic review
Highlights•Diaphragmatic #breathing benefits #GERD , anxiety, and post-COVID-19 syndrome.•Efficacy varies; evidence for COPD is inconsistent, poor for post-cardiac surgery.•The evidence base is constrained by methodologically weak and heterogeneous studies.•Diaphragmatic breathing is a promising, low-cost, and safe adjunctive therapy. BackgroundDiaphragmatic breathing (DB) is widely used clinically, but a comprehensive synthesis of randomized controlled trial (RCT) evidence… Continue reading The health effects of #diaphragmatic #breathing: A systematic review
Effects of #Electroacupuncture at #ST36 on Visceral Pain and Inflammatory Markers in #IBS Rats
Irritable bowel syndrome (IBS) is characterized by recurrent visceral pain associated with low-grade gut inflammation. Electroacupuncture (EA) at acupoint ST36 (Zusanli) is reputed to alleviate gastrointestinal disorders, but its effects on IBS-related visceral hypersensitivity and inflammation remain to be fully elucidated. This study evaluated whether EA at ST36 attenuates visceral pain and modulates key inflammatory… Continue reading Effects of #Electroacupuncture at #ST36 on Visceral Pain and Inflammatory Markers in #IBS Rats
2 Medical News 