Clinical efficacy study on the efficacy and safety of #acupuncture for post- #stroke #dysphagia based on the regulation of the swallowing neural circuit: protocol for a multicenter, open-label, randomized controlled trial

Introduction: Post-stroke dysphagia (PSD) is a common complication of stroke. Rehabilitation training and acupuncture have been suggested as current effective therapies, but high-quality evidence of acupuncture is insufficient. A meta-analysis has shown that acupuncture may be an effective adjunctive treatment for improving swallowing function, but the guidelines do not provide sufficient recommendations. Therefore, clinical and… Continue reading Clinical efficacy study on the efficacy and safety of #acupuncture for post- #stroke #dysphagia based on the regulation of the swallowing neural circuit: protocol for a multicenter, open-label, randomized controlled trial

Effect of core stabilization exercises on #lumbar multifidus morphology and functional outcomes in chronic non-specific low #back pain: a randomized controlled trial

Background: Chronic non-specific low back pain (CNSLBP) is often associated with morphological changes in the lumbar multifidus muscle (LMF), such as reduced cross-sectional area (CSA) and increased fat infiltration, compromising spinal stability and function. Core stabilization exercises aim to enhance neuromuscular control by targeting deep trunk muscles. However, few randomized trials have investigated their effects… Continue reading Effect of core stabilization exercises on #lumbar multifidus morphology and functional outcomes in chronic non-specific low #back pain: a randomized controlled trial

#Electroacupuncture ameliorates skeletal muscle #insulin resistance in #diabetic rats via PPAR-γ/NF-κB signaling pathway

Objectives: To observe the effect of electroacupuncture (EA) at "Sanyinjiao" (SP6) and "Zusanli" (ST36) on the expressions of peroxisome proliferator-activated γ receptor (PPAR-γ), nuclear factor-κB (NF-κB) and glucose transporter 4 (GLUT4) in skeletal muscle of Zucker Diabetic Fatty (ZDF) rats with type 2 diabetes mellitus (T2DM), so as to explore its possible mechanism in improving… Continue reading #Electroacupuncture ameliorates skeletal muscle #insulin resistance in #diabetic rats via PPAR-γ/NF-κB signaling pathway

Effect of #acupuncture intervention combined with lateral approach #sciatic nerve block on postoperative analgesia in patients after total #knee #arthroplasty

Objectives: To explore the effect of acupuncture intervention combined with lateral approach sciatic nerve block (LSNB) on postoperative analgesia in patients after total knee arthroplasty (TKA).Methods: A total of 90 patients scheduled for TKA between May 2022 and May 2024 were selected as the study subjects. They were randomly divided into a control group and… Continue reading Effect of #acupuncture intervention combined with lateral approach #sciatic nerve block on postoperative analgesia in patients after total #knee #arthroplasty

Effects of glucagon-like peptide-1 on systemic hemodynamics, kidney function, and intrarenal oxygenation in sheep with sepsis-associated acute kidney injury

Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) reduce chronic kidney disease progression in people with type 2 diabetes mellitus. Sepsis is the leading cause of acute kidney injury (AKI). This study investigated whether GLP-1 is renoprotective in an ovine model of gram-negative septic AKI. Sixteen healthy merino ewes were surgically instrumented to measure mean arterial pressure,… Continue reading Effects of glucagon-like peptide-1 on systemic hemodynamics, kidney function, and intrarenal oxygenation in sheep with sepsis-associated acute kidney injury

Three vs 12-month #DAPT after implantation of biodegradable-polymer sirolimus-eluting coronary #stent : a randomised clinical trial

Early discontinuation of dual antiplatelet therapy (DAPT) within 3 months after implantation of drug-eluting stents may reduce bleeding risk without increasing ischaemic events. This study aimed to assess whether 3-month DAPT is as safe as the conventional 12-month regimen in patients treated with Firehawk stents, which have demonstrated 99.9% reendothelialisation at 3 months by optical… Continue reading Three vs 12-month #DAPT after implantation of biodegradable-polymer sirolimus-eluting coronary #stent : a randomised clinical trial

Improving non-invasive #glucose estimation with monthly calibrated #photoplethysmography and implicit #HbA1c

Background: Most noninvasive blood glucose technologies, especially wearable photoplethysmography devices, require multiple calibrations and are often limited to narrow cohorts such as unmedicated or mild cases. We assess whether a single pretest once per month can meet clinical accuracy while broadening applicability through cohort-specific models.Methods: We develop models for three groups: (i) individuals not using… Continue reading Improving non-invasive #glucose estimation with monthly calibrated #photoplethysmography and implicit #HbA1c

#Acupuncture for #fibromyalgia syndrome: an overview of systematic reviews and meta-analyses

Objective: Numerous systematic reviews (SRs) and meta-analyses (MAs) have investigated the clinical effectiveness of acupuncture therapy (AT) for fibromyalgia syndrome (FMS); however, the quality and consistency of the evidence remain unclear. This study aimed to evaluate the methodological quality and strength of evidence in published SRs and MAs on the efficacy and safety of AT… Continue reading #Acupuncture for #fibromyalgia syndrome: an overview of systematic reviews and meta-analyses

The effectiveness of Zhi-Shi plaster acupoint therapy combined with lactulose in the treatment of geriatrics functional constipation: a randomized controlled trial

Objective: This study aimed to evaluate the effectiveness and adverse effects of Zhi-Shi plaster acupoint therapy combined with Lactulose in the Treatment of geriatrics Functional Constipation.Methods: A total of 62 geriatrics Functional Constipation patients were randomly assigned to the intervention group (n = 31) and control group (n = 31). The intervention group received oral lactulose (20 mL daily for… Continue reading The effectiveness of Zhi-Shi plaster acupoint therapy combined with lactulose in the treatment of geriatrics functional constipation: a randomized controlled trial