Physical #activity thresholds for predicting longitudinal gait decline in adults with knee #osteoarthritis

To investigate the longitudinal relationship between physical performance (via real-life accelerometry) and physical capacity (laboratory measurement of gait speed) in patients with knee osteoarthritis (KOA), and to derive accelerometry measured thresholds associated with gait speed decline in KOA that may provide targets for disease-specific physical activity guidelines. DesignLongitudinal data from the Osteoarthritis Initiative (OAI) accelerometer… Continue reading Physical #activity thresholds for predicting longitudinal gait decline in adults with knee #osteoarthritis

The Value of Total #Knee Replacement in Patients With Knee #Osteoarthritis and a Body Mass Index of 40 kg/m2 or Greater A Cost-Effectiveness Analysis

Total knee replacement (TKR) is an effective and cost-effective strategy for treating end-stage knee osteoarthritis. Greater risk for complications among TKR recipients with a body mass index (BMI) of 40 kg/m2 or greater has raised concerns about the value of TKR in this population. Objective: To assess the value of TKR in recipients with a… Continue reading The Value of Total #Knee Replacement in Patients With Knee #Osteoarthritis and a Body Mass Index of 40 kg/m2 or Greater A Cost-Effectiveness Analysis

Effect of Telephone #Cognitive Behavioral Therapy for Insomnia in Older Adults With #Osteoarthritis Pain

Scalable delivery models of cognitive behavioral therapy for insomnia (CBT-I), an effective treatment, are needed for widespread implementation, particularly in rural and underserved populations lacking ready access to insomnia treatment. Objective To evaluate the effectiveness of telephone CBT-I vs education-only control (EOC) in older adults with moderate to severe osteoarthritis pain. Design, Setting, and Participants… Continue reading Effect of Telephone #Cognitive Behavioral Therapy for Insomnia in Older Adults With #Osteoarthritis Pain

Effect of High-Intensity Strength #Training on #Knee Pain and Knee Joint Compressive Forces Among Adults With Knee #Osteoarthritis

Thigh muscle weakness is associated with knee discomfort and osteoarthritis disease progression. Little is known about the efficacy of high-intensity strength training in patients with knee osteoarthritis or whether it may worsen knee symptoms. Objective To determine whether high-intensity strength training reduces knee pain and knee joint compressive forces more than low-intensity strength training and… Continue reading Effect of High-Intensity Strength #Training on #Knee Pain and Knee Joint Compressive Forces Among Adults With Knee #Osteoarthritis

Association between current medication use and progression of radiographic #knee #osteoarthritis: data from the Osteoarthritis Initiative

Use of specific medications may accelerate the progression of radiographic knee osteoarthritis (RKOA). Our aim was to examine the effect of medication use on the progression of RKOA. Methods We used longitudinal data from the Osteoarthritis Initiative (OAI); an observational study of risk factors for knee OA. At baseline, we selected participants with RKOA (KL… Continue reading Association between current medication use and progression of radiographic #knee #osteoarthritis: data from the Osteoarthritis Initiative

Efficacy and safety of #antidepressants for the treatment of back pain and #osteoarthritis: systematic review and meta-analysis

.. 33 trials (5318 participants) were included. Moderate certainty evidence showed that serotonin-noradrenaline reuptake inhibitors (SNRIs) reduced back pain (mean difference −5.30, 95% confidence interval −7.31 to −3.30) at 3-13 weeks and low certainty evidence that SNRIs reduced osteoarthritis pain (−9.72, −12.75 to −6.69) at 3-13 weeks. Very low certainty evidence showed that SNRIs reduced… Continue reading Efficacy and safety of #antidepressants for the treatment of back pain and #osteoarthritis: systematic review and meta-analysis

The Effect of Flat Flexible Versus Stable Supportive #Shoes on Knee #Osteoarthritis Symptoms

Experts recommend that persons with knee osteoarthritis wear stable supportive shoes; however, evidence suggests that flat flexible shoes may be more beneficial.. ..Of 164 participants recruited, 161 (98%) completed 6-month primary outcomes. No evidence was found that flat flexible shoes were superior to stable supportive shoes in primary outcomes. Evidence did show a between-group difference… Continue reading The Effect of Flat Flexible Versus Stable Supportive #Shoes on Knee #Osteoarthritis Symptoms

#Acupuncture of different treatment frequencies in knee #osteoarthritis: a pilot randomised controlled trial

This 16-week randomised controlled trial (8-week treatment followed by 8-week follow-up) evaluated the symptomatic improvement in patients with knee osteoarthritis on 3 sessions per week of acupuncture (TSWA) compared to 1 session per week of acupuncture (OSWA). Sixty participants were randomised to either the TSWA or the OSWA group in a 1:1 ratio. The primary… Continue reading #Acupuncture of different treatment frequencies in knee #osteoarthritis: a pilot randomised controlled trial

Effectiveness of #Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee #Osteoarthritis

To determine the efficacy of Curcuma longa extract (CL) for reducing knee symptoms and effusion–synovitis in patients with symptomatic knee osteoarthritis and knee effusion–synovitis.. ..2 capsules of CL (n = 36) or matched placebo (n = 34) per day for 12 weeks. Measurements: The 2 primary outcomes were changes in knee pain on a visual… Continue reading Effectiveness of #Curcuma longa Extract for the Treatment of Symptoms and Effusion–Synovitis of Knee #Osteoarthritis