The impact of timing of in utero marijuana exposure on fetal growth

Objective: To examine whether timing of in utero marijuana exposure independently and negatively impacts fetal growth, and if these effects are global or specific to certain growth parameters.Study design: The two study groups were marijuana users (N = 109) and a randomly selected control group of biochemically verified non-users (n = 171). Study data were obtained via manual abstraction of electronic medical records.Results: After control for… Continue reading The impact of timing of in utero marijuana exposure on fetal growth

Chest CT Findings in Marijuana Smokers

BackgroundGlobal consumption of marijuana is increasing, but there is a paucity of evidence concerning associated lung imaging findings.PurposeTo use chest CT to investigate the effects of marijuana smoking in the lung.Materials and MethodsThis retrospective case-control study evaluated results of chest CT examinations (from October 2005 to July 2020) in marijuana smokers, nonsmoker control patients, and… Continue reading Chest CT Findings in Marijuana Smokers

Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

Epidemiological studies reveal that marijuana increases the risk of cardiovascular disease (CVD); however, little is known about the mechanism. Δ9-tetrahydrocannabinol (Δ9-THC), the psychoactive component of marijuana, binds to cannabinoid receptor 1 (CB1/CNR1) in the vasculature and is implicated in CVD. A UK Biobank analysis found that cannabis was an risk factor for CVD. We found… Continue reading Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation

#Marijuana Use in Patients With #Cardiovascular Disease: JACC Review Topic of the Week

Marijuana use is increasing as more states are legalizing cannabis for both medicinal and recreational purposes. National survey data estimate that >2 million Americans with established cardiovascular diseases currently use or have used marijuana in its variety of forms, including inhalation and vaping. Cannabinoid receptors are distributed in multiple tissue beds and cells, including platelets,… Continue reading #Marijuana Use in Patients With #Cardiovascular Disease: JACC Review Topic of the Week

Association Between #Marijuana Use and Risk of #Cancer A Systematic Review and Meta-analysis

.. In pooled analysis of case-control studies, ever use of marijuana was not associated with head and neck squamous cell carcinoma or oral cancer. In pooled analysis of 3 case-control studies, more than 10 years of marijuana use (joint-years not reported) was associated with TGCT (OR, 1.36; 95% CI, 1.03-1.81; P = .03; I2 = 0%) and nonseminoma TGCT… Continue reading Association Between #Marijuana Use and Risk of #Cancer A Systematic Review and Meta-analysis