Neural Signatures of Pain Modulation in Short-Term and Long-Term Mindfulness Training: A Randomized Active-Control Trial

Mindfulness-based interventions are widely used to target pain, yet their neural mechanisms of action are insufficiently understood. The authors studied neural and subjective pain response in a randomized active-control trial of mindfulness-based stress reduction (MBSR) alongside long-term meditation practitioners.Methods:Healthy participants (N=115) underwent functional neuroimaging during a thermal acute pain task before and after random assignment… Continue reading Neural Signatures of Pain Modulation in Short-Term and Long-Term Mindfulness Training: A Randomized Active-Control Trial

Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls

Psilocybin microdosing involves repeated self-administration of mushrooms containing psilocybin at doses small enough to not impact regular functioning. Microdose practices are diverse and include combining psilocybin with substances such as lion’s mane mushrooms (Hericium erinaceus; HE) and niacin (vitamin-B3). Public uptake of microdosing has outpaced evidence, mandating further prospective research. Using a naturalistic, observational design,… Continue reading Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls

High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression

ObjectiveVitamins B6 and B12 are involved in metabolic processes that decrease neural excitation and increase inhibition. This double-blind study investigated the effects of supplementation for 1 month with a high-dose of B6 or B12, compared to placebo, on a range of behavioural outcome measures connected to the balance between neural inhibition and excitation.Methods478 young adults… Continue reading High-dose Vitamin B6 supplementation reduces anxiety and strengthens visual surround suppression

Early childhood allergy linked with development of attention deficit hyperactivity disorder and autism spectrum disorder

BackgroundPrevious studies reported controversial results regarding the association between allergic disorders and attention deficit hyperactivity disorder (ADHD)/autism spectrum disorder (ASD). The aim of this article was to investigate whether allergic disorders are associated with ADHD/ASD in a large cohort of pediatric patients. MethodsA retrospective study using the pediatric (0–18 year) database (ICD-9-CM codes) of Clalit Health… Continue reading Early childhood allergy linked with development of attention deficit hyperactivity disorder and autism spectrum disorder

I Hear My Voice; Therefore I Spoke: The Sense of Agency Over Speech Is Enhanced by Hearing One’s Own VoiceHear My Voice; Therefore I Spoke: The Sense of Agency Over Speech Is Enhanced by Hearing One’s Own Voice

The subjective experience of causing an action is known as the sense of agency. Dysfunctional sense of agency over speech has been suggested as a cause of auditory hallucinations. However, agency over speech has not been extensively characterized in previous empirical studies. Here, we manipulated self-voice identity, an indicator of self, embedded in the acoustic… Continue reading I Hear My Voice; Therefore I Spoke: The Sense of Agency Over Speech Is Enhanced by Hearing One’s Own VoiceHear My Voice; Therefore I Spoke: The Sense of Agency Over Speech Is Enhanced by Hearing One’s Own Voice

Cognitive Behavioral Therapy for Veterans With Comorbid Posttraumatic Headache and Posttraumatic Stress Disorder SymptomsA Randomized Clinical Trial

Importance Posttraumatic headache is the most disabling complication of mild traumatic brain injury. Posttraumatic stress disorder (PTSD) symptoms are often comorbid with posttraumatic headache, and there are no established treatments for this comorbidity. Objective To compare cognitive behavioral therapies (CBTs) for headache and PTSD with treatment per usual (TPU) for posttraumatic headache attributable to mild… Continue reading Cognitive Behavioral Therapy for Veterans With Comorbid Posttraumatic Headache and Posttraumatic Stress Disorder SymptomsA Randomized Clinical Trial

Childhood trauma and schizotypy in non-clinical samples: A systematic review and meta-analysis

The association of early life adversities and psychosis symptoms is well documented in clinical populations; however, whether this relationship also extends into subclinical psychosis remains unclear. In particular, are early life adversities associated with increased levels of schizotypal personality traits in non-clinical samples? We conducted a systematic review and meta-analysis of associations between early life… Continue reading Childhood trauma and schizotypy in non-clinical samples: A systematic review and meta-analysis

Psychiatric Patients Who Do Not Believe They Deserve to Get Better

Seven years ago, our clinical research group began towork in our hospital’s partial hospital program. Patientsare most commonly referred to the partial hospital becausethey are in crisis, are being transferred from a more intensivelevel of care (ie, inpatient services), or are referred fromoutpatient settings because they have not responded totreatment. While the average length of… Continue reading Psychiatric Patients Who Do Not Believe They Deserve to Get Better

The Impostor Phenomenon and causal attributions of positive feedback on intelligence tests

Highlights•The Impostor Phenomenon (IP) is characterized by attributional styles. •Participants completed numerical and verbal intelligence tasks. •Participants received positive feedback on their performance. •IP does not relate to actual performance in intelligence tests. •IP relates to attributing positive feedback to external-instable-specific causes. AbstractThe Impostor Phenomenon (IP) is characterized by an external-instable-specific attributional style (i.e., Impostors… Continue reading The Impostor Phenomenon and causal attributions of positive feedback on intelligence tests