Category: Infectivology

Consistent Detection of 2019 Novel #Coronavirus in #Saliva

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The 2019 novel coronavirus (2019-nCoV) was detected in the self-collected saliva of 91.7% (11/12) of patients. Serial saliva viral load monitoring generally showed a declining trend. Live virus was detected in saliva by viral culture. Saliva is a promising noninvasive specimen for diagnosis, monitoring, and infection control in patients with 2019-nCoV infection. https://bit.ly/399IDoR PDF file… Continue reading Consistent Detection of 2019 Novel #Coronavirus in #Saliva

Pharmacologic Therapies in Patients With Exacerbation of Chronic #Obstructive #Pulmonary Disease: A Systematic Review With Meta-analysis

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..Compared with placebo or management without antibiotics, antibiotics given for 3 to 14 days were associated with increased exacerbation resolution at the end of the intervention (odds ratio [OR], 2.03 [95% CI, 1.47 to 2.80]; moderate SOE) and less treatment failure at the end of the intervention (OR, 0.54 [CI, 0.34 to 0.86]; moderate SOE),… Continue reading Pharmacologic Therapies in Patients With Exacerbation of Chronic #Obstructive #Pulmonary Disease: A Systematic Review With Meta-analysis

Abnormal Coagulation parameters are associated with poor prognosis in patients with novel #coronavirus #pneumonia

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In the recent outbreak of novel coronavirus infection in Wuhan, China, significantly abnormal coagulation parameters in severe novel coronavirus pneumonia (NCP) cases were a concern.. Conventional coagulation results and outcomes of consecutive 183 patients with confirmed NCP in Tongji hospital were retrospectively analysed. Results The overall mortality was 11.5%, the non‐survivors revealed significantly higher D‐dimer… Continue reading Abnormal Coagulation parameters are associated with poor prognosis in patients with novel #coronavirus #pneumonia

#Influenza #vaccine effectiveness 2019-2020 interim estimates

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Annual vaccination against seasonal influenza is recommended for all U.S. persons aged ≥6 months. Effectiveness of seasonal influenza vaccine varies by season. What is added by this report? According to data from the U.S. Influenza Vaccine Effectiveness Network on 4,112 children and adults with acute respiratory illness during October 23, 2019–January 25, 2020, the overall… Continue reading #Influenza #vaccine effectiveness 2019-2020 interim estimates

Empirical Anti-#MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for #Pneumonia

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..Compared with standard therapy alone, in weighted propensity score analysis, empirical anti-MRSA therapy plus standard therapy was significantly associated with an increased adjusted risk of death (adjusted risk ratio [aRR], 1.4 [95% CI, 1.3-1.5]), kidney injury (aRR, 1.4 [95% CI, 1.3-1.5]), and secondary C difficile infections (aRR, 1.6 [95% CI, 1.3-1.9]), vancomycin-resistant Enterococcus spp infections… Continue reading Empirical Anti-#MRSA vs Standard Antibiotic Therapy and Risk of 30-Day Mortality in Patients Hospitalized for #Pneumonia

#Hand‐Hygiene Mitigation Strategies Against Global #Disease Spreading through the Air Transportation Network

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The risk for a global transmission of flu‐type viruses is strengthened by the physical contact between humans and accelerated through individual mobility patterns.. ..Here, we use epidemiological modeling and data‐driven simulations to elucidate the role of individual engagement with hand hygiene inside airports in conjunction with human travel on the global spread of epidemics. We… Continue reading #Hand‐Hygiene Mitigation Strategies Against Global #Disease Spreading through the Air Transportation Network

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel #Coronavirus–Infected Pneumonia in Wuhan, China

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..Of 138 hospitalized patients with NCIP, the median age was 56 years (interquartile range, 42-68; range, 22-92 years) and 75 (54.3%) were men. Hospital-associated transmission was suspected as the presumed mechanism of infection for affected health professionals (40 [29%]) and hospitalized patients (17 [12.3%]). Common symptoms included fever (136 [98.6%]), fatigue (96 [69.6%]), and dry… Continue reading Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel #Coronavirus–Infected Pneumonia in Wuhan, China