Patients with coronavirus disease-19 (COVID-19) are at high risk for thrombotic arterial and venous occlusions. However, bleeding complications have also been observed in some patients. Understanding the balance between coagulation and fibrinolysis will help inform optimal approaches to thrombosis prophylaxis and potential utility of fibrinolytic-targeted therapies. 118 hospitalized COVID-19 patients and 30 healthy controls were… Continue reading #Plasma tissue plasminogen activator and plasminogen activator inhibitor-1 in hospitalized #COVID-19 patients
Category: Infectivology
#COVID-19 Outcomes Among Persons Living With or Without Diagnosed #HIV Infection in New York State
New York State has been an epicenter for both the US coronavirus disease 2019 (COVID-19) and HIV/AIDS epidemics. Persons living with diagnosed HIV may be more prone to COVID-19 infection and severe outcomes, yet few studies have assessed this possibility at a population level.. ..A total of 2988 persons living with diagnosed HIV (2109 men… Continue reading #COVID-19 Outcomes Among Persons Living With or Without Diagnosed #HIV Infection in New York State
Increased #alcohol use during the #COVID-19 pandemic: The effect of mental health and age in a cross-sectional sample of social media users in the U.S.
The COVID-19 pandemic has triggered a public health crisis of unprecedented scale. Increased alcohol use has been extensively documented during other crises, particularly among persons with anxiety and depression. Despite COVID-19's differential impact by age, the association of age, mental health and alcohol use during the pandemic has not been explored. This study aimed to… Continue reading Increased #alcohol use during the #COVID-19 pandemic: The effect of mental health and age in a cross-sectional sample of social media users in the U.S.
A Little #Autonomy Support Goes a Long Way: Daily Autonomy‐Supportive Parenting, Child Well‐Being, Parental Need Fulfillment, and Change in Child, Family, and Parent Adjustment Across the Adaptation to the #COVID‐19 Pandemic
This study examined the effects of daily parental autonomy support on changes in child behavior, family environment, and parental well‐being across 3 weeks during the COVID‐19 pandemic in Germany. Day‐to‐day associations among autonomy‐supportive parenting, parental need fulfillment, and child well‐being were also assessed. Parents (longitudinal N = 469; Mage = 42.93, SDage = 6.40) of… Continue reading A Little #Autonomy Support Goes a Long Way: Daily Autonomy‐Supportive Parenting, Child Well‐Being, Parental Need Fulfillment, and Change in Child, Family, and Parent Adjustment Across the Adaptation to the #COVID‐19 Pandemic
Are Patients With Inflammatory Bowel Disease at an Increased Risk of Developing #SARS-CoV-2 than Patients Without Inflammatory #Bowel Disease? Results From a Nationwide Veterans’ Affairs Cohort Study
The clinic course of SARS-CoV-2 among patients with inflammatory bowel disease (IBD) has been extensively studied. However, there is a paucity of data on whether patients with IBD have an increased risk of developing SARS-CoV-2 with compared with patients without IBD. METHODS: We conducted a nationwide retrospective cohort study in the US Veterans’ Affairs healthcare… Continue reading Are Patients With Inflammatory Bowel Disease at an Increased Risk of Developing #SARS-CoV-2 than Patients Without Inflammatory #Bowel Disease? Results From a Nationwide Veterans’ Affairs Cohort Study
#Metformin Use Is Associated With Reduced Mortality in a Diverse Population With #COVID-19 and Diabetes
Coronavirus disease-2019 (COVID-19) is a growing pandemic with an increasing death toll that has been linked to various comorbidities as well as racial disparity. However, the specific characteristics of these at-risk populations are still not known and approaches to lower mortality are lacking.. ..The odds ratio of contracting COVID-19 was disproportionately high in Blacks/African-Americans (OR… Continue reading #Metformin Use Is Associated With Reduced Mortality in a Diverse Population With #COVID-19 and Diabetes
EUGLYCEMIC DIABETIC #KETOACIDOSIS WITH #COVID-19 INFECTION IN PATIENTS WITH TYPE 2 DIABETES TAKING #SGLT2 INHIBITORS
Diabetes mellitus is associated with poor outcomes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Diabetic ketoacidosis (DKA) has also been reported to occur with this virus. A cluster of cases of euglycemic DKA (euDKA) was identified in patients with type 2 diabetes mellitus using sodium-glucose cotransporter-2 inhibitors (SGLT2is) who developed SARS-CoV-2 infection.. ..Five… Continue reading EUGLYCEMIC DIABETIC #KETOACIDOSIS WITH #COVID-19 INFECTION IN PATIENTS WITH TYPE 2 DIABETES TAKING #SGLT2 INHIBITORS
6-month consequences of #COVID-19 in patients discharged from hospital: a cohort study
The long-term health consequences of COVID-19 remain largely unclear. The aim of this study was to describe the long-term health consequences of patients with COVID-19 who have been discharged from hospital and investigate the associated risk factors, in particular disease severity.. ..In total, 1733 of 2469 discharged patients with COVID-19 were enrolled after 736 were… Continue reading 6-month consequences of #COVID-19 in patients discharged from hospital: a cohort study
Progression of #Myopia in School-Aged Children After #COVID-19 Home Confinement
Time spent in outdoor activities has decreased owing to home confinement for the coronavirus disease 2019 (COVID-19) pandemic. Concerns have been raised about whether home confinement may have worsened the burden of myopia owing to substantially decreased time spent outdoors and increased screen time at home.. .. Of the 123 535 children included in the study,… Continue reading Progression of #Myopia in School-Aged Children After #COVID-19 Home Confinement
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