ObjectiveTo investigate the association between chrononutrition and glycemic control parameters throughout the pregnancy in women with diabetes mellitus (DM).MethodsCross-sectional study with 117 pregnant women with pregestational DM. Food consumption was assessed using 24-h dietary recalls in the second and third trimesters of pregnancy. Chrononutrition parameters included number of eating episodes, eating pattern, mealtimes, and caloric… Continue reading Evening snacks without increased nighttime caloric intake decrease fasting glucose in pregnant women with pregestational diabetes mellitus
Category: Endocrinology
Obesity Treatments and Weight Changes in Clinical Practice After Discontinuation of Semaglutide or Tirzepatide
Aims: To describe #obesity treatments in real-world settings after discontinuation of #semaglutide or #tirzepatide and variability in weight change post-discontinuation.Materials and methods: This retrospective cohort study used electronic health records from 1 January 2021, to 30 June 2025, in a large health system in Ohio and Florida. Adults with overweight or obesity who initiated injectable… Continue reading Obesity Treatments and Weight Changes in Clinical Practice After Discontinuation of Semaglutide or Tirzepatide
Team-Based Pilot Program Incorporates Food Vouchers to Improve Health in Patients with Diabetes
An evaluation of a team-based pilot program with food vouchers.DesignSingle-arm prepost mixed-method study.SettingTwo safety-net primary care clinics in San Francisco.ParticipantsBlack/African American and/or Hispanic/Latinx patients with uncontrolled #diabetes (hemoglobin A1c >8%).Intervention(s)Six-month program including pharmacist and #nutritionist visits, transportation assistance, and smoking cessation resources, plus $160 per month of grocery and produce vouchers.Main Outcome Measure(s)#Glycemic control and… Continue reading Team-Based Pilot Program Incorporates Food Vouchers to Improve Health in Patients with Diabetes
Efficacy and Safety of Acupoint Catgut Embedding for Obesity Associated with Polycystic Ovary Syndrome: A Qualitative and Quantitative Analysis
AbstractAim: #Obesity is common in women with polycystic ovary syndrome (PCOS) and can exacerbate #PCOS symptoms. Although Acupoint catgut embedding (ACE) is frequently used to treat the clinical symptoms of simple obesity, it is unclear how it will affect obesity associated with PCOS. We conducted a systematic review and meta-analysis of randomized clinical trials (RCTs)… Continue reading Efficacy and Safety of Acupoint Catgut Embedding for Obesity Associated with Polycystic Ovary Syndrome: A Qualitative and Quantitative Analysis
A Qualitative Study Exploring Diabetes Prevention Intervention Needs and Ideas Among Young Adults at High Risk for Diabetes
ObjectiveTo explore perspectives of #young adults with #prediabetes and high burden of social needs about their intervention needs and ideas for solutions to enable behavior change.DesignQualitative study with semistructured interviews.SettingOne safety-net hospital and 1 academic medical center in a US city.ParticipantsTwenty-four publicly-insured adults aged 18–26 years with prediabetes (63% female, 71% Latino/a/x, 29% Black, 61%… Continue reading A Qualitative Study Exploring Diabetes Prevention Intervention Needs and Ideas Among Young Adults at High Risk for Diabetes
Efficacy and safety of GLP-1 receptor agonists and SGLT2 inhibitors as adjuncts to insulin in type 1 diabetes: Systematic review and meta-analysis
AimsAdjunctive therapies to insulin for type 1 #diabetes mellitus (T1DM), including glucagon-like peptide-1 receptor agonists ( #GLP-1RAs ) and sodium–glucose cotransporter-2 inhibitors ( #SGLT2is ), may improve glycaemic control and reduce insulin requirements; however, safety concerns remain, particularly for diabetic ketoacidosis (DKA).Materials and MethodsPubMed, Ovid MEDLINE, Embase, Web of Science, Scopus and the Cochrane Library… Continue reading Efficacy and safety of GLP-1 receptor agonists and SGLT2 inhibitors as adjuncts to insulin in type 1 diabetes: Systematic review and meta-analysis
#Electroacupuncture ameliorates skeletal muscle #insulin resistance in #diabetic rats via PPAR-γ/NF-κB signaling pathway
Objectives: To observe the effect of electroacupuncture (EA) at "Sanyinjiao" (SP6) and "Zusanli" (ST36) on the expressions of peroxisome proliferator-activated γ receptor (PPAR-γ), nuclear factor-κB (NF-κB) and glucose transporter 4 (GLUT4) in skeletal muscle of Zucker Diabetic Fatty (ZDF) rats with type 2 diabetes mellitus (T2DM), so as to explore its possible mechanism in improving… Continue reading #Electroacupuncture ameliorates skeletal muscle #insulin resistance in #diabetic rats via PPAR-γ/NF-κB signaling pathway
Improving non-invasive #glucose estimation with monthly calibrated #photoplethysmography and implicit #HbA1c
Background: Most noninvasive blood glucose technologies, especially wearable photoplethysmography devices, require multiple calibrations and are often limited to narrow cohorts such as unmedicated or mild cases. We assess whether a single pretest once per month can meet clinical accuracy while broadening applicability through cohort-specific models.Methods: We develop models for three groups: (i) individuals not using… Continue reading Improving non-invasive #glucose estimation with monthly calibrated #photoplethysmography and implicit #HbA1c
Effect of Sodium-Glucose Co-transporter 2 ( #SGLT2 ) Inhibitors in the Management of #Hyponatremia Associated With Syndrome of Inappropriate Antidiuresis
AbstractBackground: Hyponatremia due to syndrome of inappropriate antidiuresis (SIAD) is a common and challenging electrolyte disorder, particularly in hospitalized and elderly patients. Conventional treatments, such as fluid restriction and vasopressin receptor antagonists, have limitations related to efficacy, tolerance, availability, and cost. Sodium-glucose co-transporter 2 inhibitors (SGLT2i), primarily used for type 2 diabetes, have shown potential… Continue reading Effect of Sodium-Glucose Co-transporter 2 ( #SGLT2 ) Inhibitors in the Management of #Hyponatremia Associated With Syndrome of Inappropriate Antidiuresis