LBA 06 – Clinical Effectiveness of Single Course Low-Dose #Radiation Therapy in #Knee #Osteoarthritis: Short-term Results from the Randomized, Sham-Controlled Trial

Low-dose radiation therapy (LDRT) has been historically used as a non-pharmacologic option for osteoarthritis (OA), but solid evidence from randomized trials is still limited.Materials/Methods: In this multicenter, randomized, sham-controlled trial, 114 patients with knee OA were allocated to receive sham irradiation, total 0.3 Gy/6 fractions, or total 3 Gy/6 fractions. The main inclusion criteria are… Continue reading LBA 06 – Clinical Effectiveness of Single Course Low-Dose #Radiation Therapy in #Knee #Osteoarthritis: Short-term Results from the Randomized, Sham-Controlled Trial

Stereotactic Body Radiotherapy vs #Sorafenib Alone in #Hepatocellular Carcinoma

Question  Does stereotactic body radiation therapy (SBRT) prior to systemic therapy improve overall survival compared with systemic therapy alone in patients with locally advanced hepatocellular carcinoma (HCC)?Findings  This phase 3 randomized clinical trial found that the use of SBRT prior to sorafenib was associated with clinically important but not statistically significant improved overall survival in… Continue reading Stereotactic Body Radiotherapy vs #Sorafenib Alone in #Hepatocellular Carcinoma

Low Doses of Ionizing #Radiation as a Treatment for #Alzheimer’s Disease: A Pilot Study

In 2015, a patient in hospice with Alzheimer’s disease (AD) was treated with ionizing radiation to her brain using repeated CT scans. Improvement in cognition, speech, movement, and appetite was observed. These improvements were so momentous that she was discharged from the hospice to a long-term care home. Based on this case, we conducted a… Continue reading Low Doses of Ionizing #Radiation as a Treatment for #Alzheimer’s Disease: A Pilot Study

Lower abdominal and pelvic radiation and #testicular germ cell tumor risk

Testicular germ cell tumor (TGCT) incidence has increased in recent decades along with the use and dose of diagnostic radiation. Here we examine the association between reported exposure to diagnostic radiation and TGCT risk.. ..There were 315 men with TGCT and 931 men without TGCT in our study. Compared to no exposures, risk of TGCT… Continue reading Lower abdominal and pelvic radiation and #testicular germ cell tumor risk

Occupational #radiation exposure and excess additive risk of #cataract incidence in a cohort of US radiologic technologists

..There were 11 345 cataract diagnoses and 5440 of cataract surgery during 832 462 and 888 402 person-years of follow-up, respectively. Cumulative occupational radiation exposure was associated with self-reported cataract, but not with cataract surgery, with EAR/104 person-year Gy=94 (95% CI: 47 to 143, p<0.001) and EAR/104 person-year Gy=13 (95% CI: <0 to 57, p=0.551), respectively. There was… Continue reading Occupational #radiation exposure and excess additive risk of #cataract incidence in a cohort of US radiologic technologists