Heart disease is a major global threat. Triglyceride deposit cardiomyovasculopathy (TGCV) is an emerging, noncommunicable, adult-onset heart disease, first identified in Japanese patients with heart failure (HF) requiring cardiac transplantation1,2,3. In TGCV, defective intracellular lipolysis of long-chain triglycerides (TGs) results in cellular steatosis and energy failure mainly in cardiomyocytes4 and smooth muscle cells5, leading to… Continue reading Long-term survival and durable recovery of #heart failure in patients with triglyceride deposit #cardiomyovasculopathy treated with tricaprin
Tag: Heart Failure
#Heart Failure Epidemiology and Outcomes Statistics: A Report of the Heart Failure Society of America
Summary of Top 10 Key Points1. Approximately 6.7 million Americans over 20 years of age have heart failure (HF), and the prevalence is expected to rise to 8.5 million Americans by 2030.2. The lifetime risk of HF has increased to 24%; approximately 1 in 4 persons will develop HF in their lifetime.3. Approximately 33% of… Continue reading #Heart Failure Epidemiology and Outcomes Statistics: A Report of the Heart Failure Society of America
#Olfactory Impairment and the Risk of Major Adverse #Cardiovascular Outcomes in Older Adults
BackgroundOlfactory impairment is common in older adults and may be associated with adverse cardiovascular health; however, empirical evidence is sparse. We examined olfaction in relation to the risk of coronary heart disease (CHD), stroke, and congestive heart failure (CHF).Methods and ResultsThis study included 2537 older adults (aged 75.6±2.8 years) from the Health ABC (Health, Aging, and… Continue reading #Olfactory Impairment and the Risk of Major Adverse #Cardiovascular Outcomes in Older Adults
#ELECTRONIC NICOTINE PRODUCT USE IS ASSOCIATED WITH INCIDENT #HEART FAILURE – THE ALL OF US RESEARCH PROGRAM
Trajectories of #renal biomarkers and new-onset #heart failure in the general population: Findings from the PREVEND study
Renal dysfunction is one of the most critical risk factors for developing heart failure (HF). However, the association between repeated measures of renal function and incident HF remains unclear. Therefore, this study investigated the longitudinal trajectories of urinary albumin excretion (UAE) and serum creatinine and their association with new-onset HF and all-cause mortality.Methods and resultsUsing… Continue reading Trajectories of #renal biomarkers and new-onset #heart failure in the general population: Findings from the PREVEND study
Association of Rurality With Risk of Heart Failure
Rural populations experience an increased burden of heart failure (HF) mortality compared with urban populations. Whether HF incidence is greater among rural individuals is less known. Additionally, the intersection between racial and rural health inequities is understudied.Objective To determine whether rurality is associated with increased risk of HF, independent of cardiovascular (CV) disease and socioeconomic… Continue reading Association of Rurality With Risk of Heart Failure
Effect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart FailureThe TRANSFORM-HF Randomized Clinical Trial
Although furosemide is the most commonly used loop diuretic in patients with heart failure, some studies suggest a potential benefit for torsemide.Objective To determine whether torsemide results in decreased mortality compared with furosemide among patients hospitalized for heart failure.Design, Setting, and Participants TRANSFORM-HF was an open-label, pragmatic randomized trial that recruited 2859 participants hospitalized with… Continue reading Effect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart FailureThe TRANSFORM-HF Randomized Clinical Trial
Smartphone as an electronic stethoscope: factors influencing heart sound quality
Smartphones are equipped with a high-quality microphone which may be used as an electronic stethoscope. We aim to investigate the factors influencing quality of heart sound recorded using a smartphone by non-medical users.Methods and resultsAn app named Echoes was developed for recording heart sounds using iPhone. Information on phone version and users’ characteristics including sex,… Continue reading Smartphone as an electronic stethoscope: factors influencing heart sound quality
Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial
BackgroundDietary restriction of sodium has been suggested to prevent fluid overload and adverse outcomes for patients with heart failure. We designed the Study of Dietary Intervention under 100 mmol in Heart Failure (SODIUM-HF) to test whether or not a reduction in dietary sodium reduces the incidence of future clinical events. MethodsSODIUM-HF is an international, open-label,… Continue reading Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial
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