AbstractIntroduction The pandemic of severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) disease 2019 (COVID-19) was declared in march 2020. Knowledge of COVID-19 pathophysiology soon provided a strong rationale for the early use of anti-inflammatory, antiplatelet and anticoagulant drugs, however the evidence was only slowly and partially incorporated into institutional guidelines. Unmet needs of COVID-19 outpatients were… Continue reading EARLY OUTPATIENT TREATMENT OF COVID-19: A RETROSPECTIVE ANALYSIS OF 392 CASES IN ITALY
Tag: coronavirus
Use of face masks did not impact COVID-19 incidence among 10–12-year-olds in Finland
AbstractIn fall 2021 in Finland, the recommendation to use face masks in schools for pupils ages 12 years and above was in place nationwide. Some cities recommended face masks for younger pupils as well. Our aim was to compare COVID-19 incidence among 10–12-year-olds between cities with different recommendations on the use of face masks in… Continue reading Use of face masks did not impact COVID-19 incidence among 10–12-year-olds in Finland
Oral erythema multiforme after Pfizer-BioNTech COVID-19 vaccination: a report of four cases
BackgroundThe 2019 Coronavirus disease (Covid-19) has affected thousands of people worldwide. To date, vaccines appear to be the only method to prevent and reduce mortality. Four vaccinations have been outwardly approved by European Medicine Agency (EMA) in Europe: BNT162b2 (Comirnaty-BioNTech/Pfizer), mRNA-1273 (Spikevax-Moderna), ChAdOx1 (VaxzevriaAstrazeneca), and Ad26.COV2-S (Janssen-Johnson&Johnson). After vaccination, local and systemic adverse effects can… Continue reading Oral erythema multiforme after Pfizer-BioNTech COVID-19 vaccination: a report of four cases
Evaluation of menstrual irregularities after COVID-19 vaccination: Results of the MECOVAC survey
We investigated menstrual irregularities after the first and second doses of the COVID-19 vaccine. Women answered a customised online questionnaire (ClinicalTrial.gov ID: NCT05083065) aimed to assess the vaccine type, the phase of the menstrual cycle during which the vaccine was administered, the occurrence of menstrual irregularities after the first and second doses, and how long… Continue reading Evaluation of menstrual irregularities after COVID-19 vaccination: Results of the MECOVAC survey
Early outpatient treatment for Covid19 with convalescent plasma
Polyclonal convalescent plasma may be obtained from donors who have recovered from coronavirus disease 2019 (Covid-19). The efficacy of this plasma in preventing serious complications in outpatients with recent-onset Covid-19 is uncertain. METHODSIn this multicenter, double-blind, randomized, controlled trial, we evaluated the efficacy and safety of Covid-19 convalescent plasma, as compared with control plasma, in… Continue reading Early outpatient treatment for Covid19 with convalescent plasma
Digit ratios and their asymmetries as risk factors of developmental instability and hospitalization for COVID-19
COVID-19 presents with mild symptoms in the majority of patients but in a minority it progresses to acute illness and hospitalization. Here we consider whether markers for prenatal sex hormones and postnatal stressors on developmental instability, i.e. digit ratios and their directional and unsigned asymmetries, are predictive of hospitalization. We focus on six ratios: 2D:3D;… Continue reading Digit ratios and their asymmetries as risk factors of developmental instability and hospitalization for COVID-19
New-onset of vitiligo in a child following COVID-19 vaccination
Since January 2020, the ongoing COVID-19 pandemic has been a global health emergency. Vaccination is a critical measure for containing the spread of COVID-19. At the end of 2020, several vaccines became available. Multiple adverse events (AEs) have been reported with all the available COVID-19 vaccines. This report describes a case of vitiligo in a… Continue reading New-onset of vitiligo in a child following COVID-19 vaccination
Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review
The coronavirus disease 2019 (COVID-19) pandemic has had profound and lasting consequences since 2019. Although vaccines against COVID-19 have been developed and approved under emergency use authorization, various adverse events have also been reported after COVID-19 vaccination. This review was undertaken to help clinicians recognize the possible manifestations and systemic pathogenesis, especially those related to… Continue reading Ocular Manifestations after Receiving COVID-19 Vaccine: A Systematic Review
Efficacy of a Fourth Dose of Covid-19 mRNA Vaccine against Omicron
In this open-label, nonrandomized clinical study, we assessed the immunogenicity and safety of a fourth dose of either BNT162b2 (Pfizer–BioNTech) or mRNA-1273 (Moderna) administered 4 months after the third dose in a series of three BNT162b2 doses (ClinicalTrials.gov numbers, NCT05231005. opens in new tab and NCT05230953. opens in new tab; the protocol is available with… Continue reading Efficacy of a Fourth Dose of Covid-19 mRNA Vaccine against Omicron
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