Background The potential modifiable factors influencing irritable bowel syndrome (IBS) have not been thoroughly documented. We aimed to systematically investigate the modifiable factors associated with IBS, while accounting for the impact of unobserved confounders and coexisting disorders.Methods Genetic correlation and Mendelian randomisation (MR) analyses were integrated to identify potential modifiable factors and coexisting disorders linked… Continue reading Modifiable factors for #irritable bowel syndrome: evidence from Mendelian randomisation approach
Category: psychology
#Mindfulness-based cognitive therapy versus treatment as usual after non-remission with NHS Talking Therapies high-intensity psychological therapy for depression: a UK-based clinical effectiveness and cost-effectiveness randomised, controlled, superiority trial
BackgroundNon-remission after psychological therapy for major depressive disorder is common, yet there are no established further-line treatments. In the UK National Health Service (NHS) Talking Therapies programme, about 50% of patients with depression who come to the end of the stepped care pathway do not show remission of symptoms. We aimed to investigate whether mindfulness-based… Continue reading #Mindfulness-based cognitive therapy versus treatment as usual after non-remission with NHS Talking Therapies high-intensity psychological therapy for depression: a UK-based clinical effectiveness and cost-effectiveness randomised, controlled, superiority trial
#Social media use in adolescents with and without #mental health conditions
Concerns about the relationship between social media use and adolescent mental health are growing, yet few studies focus on adolescents with clinical-level mental health symptoms. This limits our understanding of how social media use varies across mental health profiles. In this Registered Report, we analyse nationally representative UK data (N = 3,340, aged 11–19 years) including diagnostic assessments… Continue reading #Social media use in adolescents with and without #mental health conditions
A dual-pathway architecture for #stress to disrupt agency and promote #habit
Chronic stress can change how we learn and, thus, how we make decisions1,2,3,4,5. Here we investigated the neuronal circuit mechanisms that enable this. Using a multifaceted systems neuroscience approach in male and female mice, we reveal a dual-pathway, amygdala–striatal neuronal circuit architecture by which a recent history of chronic stress disrupts the action–outcome learning underlying… Continue reading A dual-pathway architecture for #stress to disrupt agency and promote #habit
#Higher income is associated with greater life satisfaction, and more #stress
Is there a cost to our well-being from increased affluence? Drawing upon responses from 2.05 million U.S. adults from the Gallup Daily Poll from 2008 to 2017 we find that with household income above ~$63,000 respondents are more likely to experience stress. This contrasts with the trend below this threshold, where at higher income the… Continue reading #Higher income is associated with greater life satisfaction, and more #stress
The Spiral of #Attention, Arousal, and Release: A Comparative Phenomenology of Jhāna Meditation and Speaking in Tongues
Buddhist Jhāna meditation and the Christian practice of speaking in tongues appear wildly distinct. These spiritual techniques differ in their ethical, theological, and historical frames and seem, from the outside, to produce markedly different states of consciousness-one a state of utter calm and the other of high emotional arousal. Yet, our phenomenological interviews with experienced… Continue reading The Spiral of #Attention, Arousal, and Release: A Comparative Phenomenology of Jhāna Meditation and Speaking in Tongues
The tradeoff of #solitude? #Restoration and relatedness across shades of solitude
Social interaction and solitude entail tradeoffs. Communicate Bond Belong (CBB) theory holds that social interaction can foster relatedness with others at the cost of social energy, whereas solitude can restore social energy at the cost of relatedness. The current study empirically tests this tradeoff of solitude and its implications for well-being by investigating different degrees… Continue reading The tradeoff of #solitude? #Restoration and relatedness across shades of solitude
Associations of accelerometer-measured #physical activity, #sedentary behaviour, and #sleep with next-day #cognitive performance in older adults: a micro-longitudinal study
BackgroundPrevious studies suggest short-term cognitive benefits of physical activity occurring minutes to hours after exercise. Whether these benefits persist the following day and the role of sleep is unclear. We examined associations of accelerometer-assessed physical activity, sedentary behaviour, and sleep with next-day cognitive performance in older adults.MethodsBritish adults aged 50-83 years (N = 76) without evidence of… Continue reading Associations of accelerometer-measured #physical activity, #sedentary behaviour, and #sleep with next-day #cognitive performance in older adults: a micro-longitudinal study
Parent-child #relationship quality predicts higher subjective #well-being in adulthood across a diverse group of countries
Theoretically and empirically, parenting is closely related to the psychological health of offspring, but long-term effects and possible international differences are not well established. In a pre-registered multilevel modeling analysis using data from the Global Flourishing Study, we tested whether retrospective parent-child relationship quality predicts adult well-being in a representative sample of 202,898 adults living… Continue reading Parent-child #relationship quality predicts higher subjective #well-being in adulthood across a diverse group of countries
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