We examined the association between serum uric acid (UA) levels and cancer incidence through a conventional observational and two-sample Mendelian randomization (MR) study in the same population (triangulation). We followed 13,695 individuals aged 35-69 years for cancer incidence (total, gastric, colorectal, lung, prostate, and breast cancers) over a median period of 10.6 years. The conventional… Continue reading Triangulating Evidence on Serum Uric Acid and Cancer Risk: Consistent Inverse Associations With Lung Cancer
Tag: uric-acid
Blood biomarker profiles and exceptional #longevity: comparison of centenarians and non-centenarians in a 35-year follow-up of the Swedish AMORIS cohort
Comparing biomarker profiles measured at similar ages, but earlier in life, among exceptionally long-lived individuals and their shorter-lived peers can improve our understanding of aging processes. This study aimed to (i) describe and compare biomarker profiles at similar ages between 64 and 99 among individuals eventually becoming centenarians and their shorter-lived peers, (ii) investigate the association… Continue reading Blood biomarker profiles and exceptional #longevity: comparison of centenarians and non-centenarians in a 35-year follow-up of the Swedish AMORIS cohort