Transition between #prediabetic and #diabetic stages in an urban community in india: a decade-long retrospective cohort study

The rising prevalence of prediabetes has increased the risk of diabetes, particularly among younger populations, if timely interventions are not implemented. In India, the limited availability of cohort-based incidence studies underscores the need for retrospective analyses using hospital-based electronic medical information systems (EMIS). This study estimates the transition probabilities and duration of stay in the… Continue reading Transition between #prediabetic and #diabetic stages in an urban community in india: a decade-long retrospective cohort study

Effect of #broccoli sprout extract and baseline gut microbiota on fasting blood #glucose in #prediabetes: a randomized, placebo-controlled trial

More effective treatments are needed for impaired fasting glucose or glucose intolerance, known as prediabetes. Sulforaphane is an isothiocyanate that reduces hepatic gluconeogenesis in individuals with type 2 diabetes and is well tolerated when provided as a broccoli sprout extract (BSE). Here we report a randomized, double-blind, placebo-controlled trial in which drug-naive individuals with prediabetes… Continue reading Effect of #broccoli sprout extract and baseline gut microbiota on fasting blood #glucose in #prediabetes: a randomized, placebo-controlled trial

#Gout risk in adults with pre-#diabetes initiating metformin

Objective Despite the strong association between gout and pre-diabetes, the role of metformin in gout among individuals with pre-diabetes remains uncertain. We compared the incidence rates of gout in adults with pre-diabetes starting metformin with those not using antidiabetic treatments.Methods We conducted a new-user, propensity score-matched cohort study using electronic health records from an academic health system… Continue reading #Gout risk in adults with pre-#diabetes initiating metformin

Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes

The role of vitamin D in people who are at risk for type 2 diabetes remains unclear.Purpose:To evaluate whether administration of vitamin D decreases risk for diabetes among people with prediabetes.Data Sources:PubMed, Embase, and ClinicalTrials.gov from database inception through 9 December 2022.Study Selection:Eligible trials that were specifically designed and conducted to test the effects of… Continue reading Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes