Antibiotic use is a risk factor for development of inflammatory bowel diseases (IBDs). IBDs are characterized by a damaged mucus layer, which does not separate the intestinal epithelium from the microbiota. Here, we hypothesized that antibiotics affect the integrity of the mucus barrier, which allows bacterial penetrance and predisposes to intestinal inflammation. We found that… Continue reading #Antibiotics damage the #colonic mucus barrier in a #microbiota-independent manner
Tag: mucosal
Mucosal immune response in BNT162b2 COVID-19 vaccine recipients
Although the BNT162b2 COVID-19 vaccine is known to induce IgG neutralizing antibodies in serum protecting against COVID-19, it has not been studied in detail whether it could generate specific immunity at mucosal sites, which represent the primary route of entry of SARS-CoV-2. MethodsSamples of serum and saliva of 60 BNT162b2-vaccinated healthcare workers were collected at… Continue reading Mucosal immune response in BNT162b2 COVID-19 vaccine recipients
2 Medical News 