Bilateral high-frequency hearing loss is associated with elevated blood #pressure and increased hypertension risk in occupational #noise exposed workers

..bilateral high-frequency hearing loss (BHFHL) Increasing years of occupational noise exposure and BHFHL were significantly associated with systolic and diastolic blood pressure increase (all P<0.001). The lineal trend was only significant in males, with adjusted ORs for hypertension gradually increasing with increasing years of occupational noise exposure (P<0.001). Furthermore, subjects having mild and high BHFHL… Continue reading Bilateral high-frequency hearing loss is associated with elevated blood #pressure and increased hypertension risk in occupational #noise exposed workers

Comprehensive comparative effectiveness and safety of first-line #antihypertensive drug classes: a systematic, multinational, large-scale analysis

..Most estimates revealed no effectiveness differences between classes; however, #thiazide or thiazide-like diuretics showed better primary effectiveness than angiotensin-converting enzyme inhibitors: acute myocardial infarction (HR 0·84, 95% CI 0·75–0·95), hospitalisation for heart failure (0·83, 0·74–0·95), and stroke (0·83, 0·74–0·95) risk while on initial treatment. Safety profiles also favoured thiazide or thiazide-like diuretics over angiotensin-converting enzyme… Continue reading Comprehensive comparative effectiveness and safety of first-line #antihypertensive drug classes: a systematic, multinational, large-scale analysis

Bedtime hypertension treatment improves #cardiovascular risk reduction: the Hygia Chronotherapy Trial

In this multicentre, controlled, prospective endpoint trial, 19 084 hypertensive patients (10 614 men/8470 women, 60.5 ± 13.7 years of age) were assigned (1:1) to ingest the entire daily dose of ≥1 hypertension medications at bedtime (n = 9552) or all of them upon awakening (n = 9532) ..Patients of the bedtime, compared with the upon-waking, treatment-time regimen showed significantly lower hazard… Continue reading Bedtime hypertension treatment improves #cardiovascular risk reduction: the Hygia Chronotherapy Trial

Population-Attributable Risk for Cardiovascular Disease Associated With #Hypertension in #Black Adults

..The multivariable-adjusted HR associated with hypertension was 1.91 (95% CI, 1.48-2.46) for CVD, 2.41 (95% CI,1.59-3.66) for coronary heart disease, 1.52 (95% CI, 1.01-2.30) for heart failure, and 2.20 (95% CI, 1.44-3.36) for stroke. The prevalence of hypertension was 53.2% among non-Hispanic black individuals. The PAR associated with hypertension was 32.5% (95% CI, 20.5%-43.6%) for… Continue reading Population-Attributable Risk for Cardiovascular Disease Associated With #Hypertension in #Black Adults

Periodontitis is associated with hypertension: a systematic review and meta-analysis

... Diagnoses of moderate-severe PD [odds ratio (OR) = 1.22; 95% confidence interval (CI): 1.10–1.35] and severe PD (OR = 1.49; 95% CI: 1.09–2.05) were associated with hypertension. Prospective studies confirmed PD diagnosis increased likelihood of hypertension occurrence (OR = 1.68; 95% CI: 0.85–3.35). Patients with PD exhibited higher mean SBP [weighted mean difference (WMD) of 4.49 mmHg; 95% CI: 2.88–6.11] and… Continue reading Periodontitis is associated with hypertension: a systematic review and meta-analysis