Background: There is currently a lack of evidence on the optimal loop diuretic dosing strategy in cases of acute decompensated heart failure (ADHF). Current consensus recommendations suggest starting with a dose of at least 2 times the patient’s home loop diuretic dose. Objective: This study assessed whether higher initial loop diuretic doses are associated with… Continue reading An Analysis of Initial Loop #Diuretic Dosing Strategies and Its Association with Time to #Decongestion
Tag: diuretic
Effect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart FailureThe TRANSFORM-HF Randomized Clinical Trial
Although furosemide is the most commonly used loop diuretic in patients with heart failure, some studies suggest a potential benefit for torsemide.Objective To determine whether torsemide results in decreased mortality compared with furosemide among patients hospitalized for heart failure.Design, Setting, and Participants TRANSFORM-HF was an open-label, pragmatic randomized trial that recruited 2859 participants hospitalized with… Continue reading Effect of Torsemide vs Furosemide After Discharge on All-Cause Mortality in Patients Hospitalized With Heart FailureThe TRANSFORM-HF Randomized Clinical Trial
Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With #Hypertension
Calcium channel blockers (CCBs) are commonly prescribed agents for hypertension that can cause peripheral edema. A prescribing cascade occurs when the edema is misinterpreted as a new medical condition and a diuretic is subsequently prescribed to treat the edema. The extent to which this prescribing cascade occurs at a population level is not well understood..… Continue reading Evaluation of a Common Prescribing Cascade of Calcium Channel Blockers and Diuretics in Older Adults With #Hypertension
Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia
BMI, alcohol intake, adherence to a DASH‐style diet, and diuretic use were all associated with serum urate levels and the presence of hyperuricemia in a dose‐response manner. The corresponding PARs of hyperuricemia cases for overweight/obesity (prevalence, 60%), non‐adherence to a DASH‐style diet (prevalence, 82%), alcohol use (prevalence, 48%), and diuretic use (prevalence, 8%) were 44%… Continue reading Population Impact Attributable to Modifiable Risk Factors for Hyperuricemia
2 Medical News 