INTRODUCTIONIn mammals, the early-life period after birth is a time of profound immune development during which the generation of appropriate responses to newly encountered commensal and environmental antigens is crucial for maintaining health. Breast milk is positioned to regulate nascent mucosal immune responses through the delivery of live microbes, commensal-selecting oligosaccharides, maternal cells, and immunomodulatory… Continue reading Breast #milk IgG engages the mouse #neonatal #immune system to instruct responses to #gut #antigens
Tag: breastfeeding
Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity
Breast milk IgG adds valueAlthough the most abundant class of antibody present in breast milk is IgA, maternal IgG antibodies also get transferred into breast milk via the neonatal Fc receptor. Sanidad et al. used mouse models to investigate the capacity of breast milk IgG to protect against pathogens and promote the establishment of a… Continue reading Maternal gut microbiome–induced IgG regulates neonatal gut microbiome and immunity
To what extent does confounding explain the association between breastfeeding duration and cognitive development up to age 14? Findings from the UK Millennium Cohort Study
BackgroundBreastfeeding duration is associated with improved cognitive development in children, but it is unclear whether this is a causal relationship or due to confounding. This study evaluates whether the observed association is explained by socioeconomic position (SEP) and maternal cognitive ability. MethodsData from 7,855 singletons born in 2000–2002 and followed up to age 14 years… Continue reading To what extent does confounding explain the association between breastfeeding duration and cognitive development up to age 14? Findings from the UK Millennium Cohort Study
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